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  1. Article

    Open Access

    Timing and cell specificity of senescence drives postnatal lung development and injury

    Senescence causes age-related diseases and stress-related injury. Paradoxically, it is also essential for organismal development. Whether senescence contributes to lung development or injury in early life rema...

    Hongwei Yao, Joselynn Wallace, Abigail L. Peterson… in Nature Communications (2023)

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  2. Article

    Open Access

    Upregulating carnitine palmitoyltransferase 1 attenuates hyperoxia-induced endothelial cell dysfunction and persistent lung injury

    Bronchopulmonary dysplasia (BPD) is a chronic lung disease in premature infants that may cause long-term lung dysfunction. Accumulating evidence supports the vascular hypothesis of BPD, in which lung endotheli...

    Jason L. Chang, Jiannan Gong, Salu Rizal, Abigail L. Peterson… in Respiratory Research (2022)

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    Article

    Short exposure to hyperoxia causes cultured lung epithelial cell mitochondrial dysregulation and alveolar simplification in mice

    Prolonged exposure to high oxygen concentrations in premature infants, although lifesaving, can induce lung oxidative stress and increase the risk of develo** BPD, a form of chronic lung disease. The lung al...

    David Garcia, Jennifer F. Carr, Felix Chan, Abigail L. Peterson… in Pediatric Research (2021)