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Article
Open AccessDemonstration of targeted crossovers in hybrid maize using CRISPR technology
Naturally occurring chromosomal crossovers (CO) during meiosis are a key driver of genetic diversity. The ability to target CO at specific allelic loci in hybrid plants would provide an advantage to the plant ...
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Article
Open AccessThe Structural Biology Knowledgebase: a portal to protein structures, sequences, functions, and methods
The Protein Structure Initiative’s Structural Biology Knowledgebase (SBKB, URL: http://sbkb.org) is an open web resource designed to turn the products of the...
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Article
Open AccessStructural genomics is the largest contributor of novel structural leverage
The Protein Structural Initiative (PSI) at the US National Institutes of Health (NIH) is funding four large-scale centers for structural genomics (SG). These centers systematically target many large families w...
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Article
Open AccessGenome-wide patterns of carbon and nitrogen regulation of gene expression validate the combined carbon and nitrogen (CN)-signaling hypothesis in plants
Carbon and nitrogen are two signals that influence plant growth and development. It is known that carbon- and nitrogen-signaling pathways influence one another to affect gene expression, but little is known ab...
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Article
Genome-wide investigation of light and carbon signaling interactions in Arabidopsis
Light and carbon are two essential signals influencing plant growth and development. Little is known about how carbon and light signaling pathways intersect or influence one another to affect gene expression.
