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  1. Article

    Author Correction: Generation and comparative analysis of an Itga8-CreERT2 mouse with preferential activity in vascular smooth muscle cells

    Ganesh Warthi, Jessica L. Faulkner, Jaser Doja in Nature Cardiovascular Research (2023)

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    Article

    Generation and comparative analysis of an Itga8-CreERT2 mouse with preferential activity in vascular smooth muscle cells

    All current smooth muscle cell (SMC) Cre mice similarly recombine floxed alleles in vascular and visceral SMCs. Here we present an Itga8-CreERT2 knock-in mouse and compare its activity with a Myh11-CreERT2 mouse....

    Ganesh Warthi, Jessica L. Faulkner, Jaser Doja in Nature Cardiovascular Research (2022)

  3. Article

    Of mice and human-specific long noncoding RNAs

    The number of human LncRNAs has now exceeded all known protein-coding genes. Most studies of human LncRNAs have been conducted in cell culture systems where various mechanisms of action have been worked out. O...

    Amr R. Ghanam, William B. Bryant, Joseph M. Miano in Mammalian Genome (2022)

  4. Article

    Open Access

    Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression

    Most single nucleotide variants (SNVs) occur in noncoding sequence where millions of transcription factor binding sites (TFBS) reside. Here, a comparative analysis of CRISPR-mediated homology-directed repair (...

    Pan Gao, Qing Lyu, Amr R. Ghanam, Cicera R. Lazzarotto, Gregory A. Newby in Genome Biology (2021)