3 Result(s)
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Alvin T Kho
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessAntagonizing cholecystokinin A receptor in the lung attenuates obesity-induced airway hyperresponsiveness
Obesity increases asthma prevalence and severity. However, the underlying mechanisms are poorly understood, and consequently, therapeutic options for asthma patients with obesity remain limited. Here we report...
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Article
Open AccessCOMPSRA: a COMprehensive Platform for Small RNA-Seq data Analysis
Small RNA-Seq is a common means to interrogate the small RNA’ome or the full spectrum of small RNAs (<200 nucleotide length) of a biological system. A pivotal problem in NGS based small RNA analysis is identif...
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Article
Open AccessMechanical forces induce an asthma gene signature in healthy airway epithelial cells
Bronchospasm compresses the bronchial epithelium, and this compressive stress has been implicated in asthma pathogenesis. However, the molecular mechanisms by which this compressive stress alters pathways rele...
