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Open AccessMechanical forces induce an asthma gene signature in healthy airway epithelial cells
Bronchospasm compresses the bronchial epithelium, and this compressive stress has been implicated in asthma pathogenesis. However, the molecular mechanisms by which this compressive stress alters pathways rele...
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Open AccessIntegration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network Module
The polygenic nature of complex diseases offers potential opportunities to utilize network-based approaches that leverage the comprehensive set of protein-protein interactions (the human interactome) to identi...
