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Article
Open AccessA unifying model to estimate the effect of heat stress in the human innate immunity during physical activities
Public health is threatened by climate change and extreme temperature events worldwide. Differences in health predispositions, access to cooling infrastructure and occupation raises an issue of heat-related he...
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Chapter and Conference Paper
Detecting Critical Transitions in the Human Innate Immune System Post-cardiac Surgery
Coronary artery bypass grafting with cardiopulmonary bypass activates the human innate immune system (HIIS) and invokes a vigorous inflammatory response that is systemic. This massive inflammatory reaction ca...
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Article
Open AccessGame of neutrophils: modeling the balance between apoptosis and necrosis
Neutrophils are one of the key players in the human innate immune system (HIIS). In the event of an insult where the body is exposed to inflammation triggering moieties (ITMs), neutrophils are mobilized toward...
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Chapter and Conference Paper
Reproducibility of Two Innate Immune System Models
In this paper we present the first step towards the development of a mathematical model of human immune system for advanced individualized healthcare, where medication plan is fine-tuned for each patient to f...
