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  1. No Access

    Article

    Epigenetic gene silencing by heterochromatin primes fungal resistance

    Heterochromatin that depends on histone H3 lysine 9 methylation (H3K9me) renders embedded genes transcriptionally silent1–3. In the fission yeast Schizosaccharomyces pombe, H3K9me heterochromatin can be transmitt...

    Sito Torres-Garcia, Imtiyaz Yaseen, Manu Shukla, Pauline N. C. B. Audergon… in Nature (2020)

  2. Article

    Open Access

    Interspecies conservation of organisation and function between nonhomologous regional centromeres

    Despite the conserved essential function of centromeres, centromeric DNA itself is not conserved. The histone-H3 variant, CENP-A, is the epigenetic mark that specifies centromere identity. Paradoxically, CENP-...

    Pin Tong, Alison L. Pidoux, Nicholas R. T. Toda, Ryan Ard… in Nature Communications (2019)

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    Article

    Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe

    During meiotic prophase, chromosomes frequently adopt a bouquet-like arrangement, with their telomeres clustered close to the nuclear periphery1,2,3. A dramatic example of this occurs in the fission yeast, Schizo...

    Elaine R. Nimmo, Alison L. Pidoux, Paul E. Perry, Robin C. Allshire in Nature (1998)