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  1. No Access

    Article

    Dual inhibition of BCL-XL and MCL-1 is required to induce tumour regression in lung squamous cell carcinomas sensitive to FGFR inhibition

    Genetic alterations in the fibroblast growth factor receptors (FGFRs) have been described in multiple solid tumours including bladder cancer, head and neck and lung squamous cell carcinoma (SqCC). However, rec...

    Clare E. Weeden, Casey Ah-Cann, Aliaksei Z. Holik, Julie Pasquet… in Oncogene (2018)

  2. Article

    Open Access

    Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing

    The presence of histone 3 lysine 9 (H3K9) methylation on the mouse inactive X chromosome has been controversial over the last 15 years, and the functional role of H3K9 methylation in X chromosome inactivation...

    Andrew Keniry, Linden J. Gearing, Natasha Jansz, Joy Liu… in Epigenetics & Chromatin (2016)

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  3. Article

    Open Access

    The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression

    The lung is constantly exposed to environmental challenges and must rapidly respond to external insults. Mechanisms involved in the repair of the damaged lung involve expansion of different epithelial cells to...

    Aliaksei Z. Holik, Caitlin E. Filby, Julie Pasquet, Kati Viitaniemi… in Respiratory Research (2015)

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