-
Article
Open AccessThe reticular lamina and basilar membrane vibrations in the transverse direction in the basal turn of the living gerbil cochlea
The prevailing theory of cochlear function states that outer hair cells amplify sound-induced vibration to improve hearing sensitivity and frequency specificity. Recent micromechanical measurements in the basa...
-
Article
Open AccessThe mechanoelectrical transducer channel is not required for regulation of cochlear blood flow during loud sound exposure in mice
The mammalian cochlea possesses unique acoustic sensitivity due to a mechanoelectrical ‘amplifier’, which requires the metabolic support of the cochlear lateral wall. Loud sound exposure sufficient to induce p...
-
Article
Open AccessA mechanoelectrical mechanism for detection of sound envelopes in the hearing organ
To understand speech, the slowly varying outline, or envelope, of the acoustic stimulus is used to distinguish words. A small amount of information about the envelope is sufficient for speech recognition, but ...
-
Article
Open AccessAnnexin A5 is the Most Abundant Membrane-Associated Protein in Stereocilia but is Dispensable for Hair-Bundle Development and Function
The phospholipid- and Ca2+-binding protein annexin A5 (ANXA5) is the most abundant membrane-associated protein of ~P23 mouse vestibular hair bundles, the inner ear’s sensory organelle. Using quantitative mass spe...
-
Article
A differentially amplified motion in the ear for near-threshold sound detection
The mammalian cochlea can detect near-threshold sound signals by mechanically amplifying sub-nanometer vibrations of the basilar membrane. This study describes vibration enhancement in the hearing organ opposi...
-
Article
Spontaneous Basilar-Membrane Oscillation (SBMO) and Coherent Reflection
In a previous report (in JARO) we have described a relatively high-frequency (15 kHz) spontaneous oscillation of the basilar membrane (SBMO) in a guinea pig ear; this oscillation was accompanied by a spontaneo...
-
Chapter
Cochlear Blood Flow
Studies of the cochlear vasculature and cochlear blood flow (CBF) have been of major interest to hearing scientists and otologists for more than a century. Throughout most of that time, this area of research h...
