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Article
Open AccessSex differences of post-Covid patients undergoing outpatient pulmonary rehabilitation
Following years of pandemic severe acute respiratory syndrome coronavirus 2 infections labelled Covid-19, long lasting impairment summarized as post-Covid syndrome (PCS) challenges worldwide healthcare. Patien...
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Article
Open AccessUnraveling cradle-to-grave disease trajectories from multilayer comorbidity networks
We aim to comprehensively identify typical life-spanning trajectories and critical events that impact patients’ hospital utilization and mortality. We use a unique dataset containing 44 million records of almo...
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Article
Open AccessEffects of lockdowns on neurobiological and psychometric parameters in unipolar depression during the COVID-19 pandemic
Defying the COVID-19 pandemic required restriction measures of unprecedented scale, that may induce and exacerbate psychiatric symptoms across the population. We aimed to assess in vivo dynamic effects of miti...
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Article
Open AccessObesity as pleiotropic risk state for metabolic and mental health throughout life
Obesity, a highly prevalent disorder and central diagnosis of the metabolic syndrome, is linked to mental health by clinical observations and biological pathways. Patients with a diagnosis of obesity may show ...
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Article
Open AccessPsychische und neurokognitive Erkrankungen und Diabetes mellitus (Update 2023)
Diabetes mellitus ist häufig mit psychischen Erkrankungen assoziiert. Depressive Störungen kommen bei diabetischen Patient:innen doppelt so häufig vor wie in der nicht-diabetischen Population. Andere psychisch...
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Article
Open AccessThe sociodemographic and clinical profile of patients with major depressive disorder receiving SSRIs as first-line antidepressant treatment in European countries
Due to favorable antidepressant (AD) efficacy and tolerability, selective-serotonin reuptake inhibitors (SSRIs) are consistently recommended as substances of first choice for the treatment of major depressive ...
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Article
Open AccessSex-Specific Differences in Mortality of Patients with a History of Bariatric Surgery: a Nation-Wide Population-Based Study
Bariatric surgery reduces mortality in patients with severe obesity and is predominantly performed in women. Therefore, an analysis of sex-specific differences after bariatric surgery in a population-based dat...
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Article
Open AccessAngekündigter assistierter Suizid in der Schweiz – Ein Fallbericht
Aktive Sterbehilfe ist aktuell in Österreich noch gesetzlich verboten. Aufgrund einer Entscheidung des Verfassungsgerichtshofs wäre assistierter Suizid ab dem Jahr 2022 gänzlich legal. Eine gesetzliche Regelun...
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Article
Open AccessPsychopharmacological Medication Has No Influence on Vitamin Status After Bariatric Surgery in Long-term Follow-up
A substantial number of patients undergoing bariatric surgery are prescribed psychopharmacological medication. However, the impact of concomitant psychopharmacological medication on the frequency of relevant v...
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Article
Open AccessA polygenic predictor of treatment-resistant depression using whole exome sequencing and genome-wide genoty**
Treatment-resistant depression (TRD) occurs in ~30% of patients with major depressive disorder (MDD) but the genetics of TRD was previously poorly investigated. Whole exome sequencing and genome-wide genotypin...
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Article
Open AccessCorrection: Epistasis of HTR1A and BDNF risk genes alters cortical 5-HT1A receptor binding: PET results link genotype to molecular phenotype in depression
In the original Article, co-author Professor Andreas Hahn was not included in the author list. This has been corrected in the XML, PDF and HTML versions of this Article.
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Article
Psychische Erkrankungen und Diabetes mellitus (Update 2019)
Diabetes mellitus ist häufig mit psychischen Erkrankungen assoziiert. Depressive Störungen kommen bei diabetischen PatientInnen doppelt so häufig vor wie in der nicht-diabetischen Population. Andere psychische...
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Article
Open AccessEpistasis of HTR1A and BDNF risk genes alters cortical 5-HT1A receptor binding: PET results link genotype to molecular phenotype in depression
Alterations of the 5-HT1A receptor and BDNF have consistently been associated with affective disorders. Two functional single nucleotide polymorphisms (SNPs), rs6295 of the serotonin 1A receptor gene (HTR1A) and ...
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Big Data Guided Interventions: Predicting Treatment Response
Big data analytics and advanced statistical learning methods held an auspicious entry into neuropsychiatric research over the last decade. Especially for common multifactorial diseases as major depressive diso...
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Article
Open AccessBrain monoamine oxidase A in seasonal affective disorder and treatment with bright light therapy
Increased cerebral monoamine oxidase A (MAO-A) levels have been shown in non-seasonal depression using positron emission tomography (PET). Seasonal affective disorder (SAD) is a sub-form of major depressive di...
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Article
Open AccessTask-relevant brain networks identified with simultaneous PET/MR imaging of metabolism and connectivity
Except for task-specific functional MRI, the vast majority of imaging studies assessed human brain function at resting conditions. However, tracking task-specific neuronal activity yields important insight how...
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Article
Sex-specific differences in diabetes prevention: a systematic review and meta-analysis
In people with prediabetes, lifestyle interventions and glucose-lowering medications are effective in preventing the progression to type 2 diabetes. It is unclear whether differences in treatment effects betwe...
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Article
Open AccessSex-specific-differences in cardiometabolic risk in type 1 diabetes: a cross-sectional study
Little is known about the impact of sex-specific differences in the management of type 1 diabetes (T1DM).
