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  1. Article

    Open Access

    Stress–strain curve and elastic behavior of the fibrotic lung with usual interstitial pneumonia pattern during protective mechanical ventilation

    Patients with acute exacerbation of lung fibrosis with usual interstitial pneumonia (EUIP) pattern are at increased risk for ventilator-induced lung injury (VILI) and mortality when exposed to mechanical venti...

    Roberto Tonelli, Raffaella Rizzoni, Salvatore Grasso in Scientific Reports (2024)

  2. No Access

    Article

    Effect of high flow nasal oxygen on inspiratory effort of patients with acute hypoxic respiratory failure and do not intubate orders

    High flow nasal oxygen (HFNO) is recommended as a first-line respiratory support during acute hypoxic respiratory failure (AHRF) and represents a proportionate treatment option for patients with do not intubat...

    Roberto Tonelli, Riccardo Fantini, Giulia Bruzzi in Internal and Emergency Medicine (2024)

  3. No Access

    Article

    “Comment on Guillain Barre’ syndrome in children and adults in the north Iran by Hosseininezhad et al

    Giuliana Galassi, Alessandra Ariatti, Alessandro Marchioni in Neurological Sciences (2023)

  4. Article

    Open Access

    Physiological effects of lung-protective ventilation in patients with lung fibrosis and usual interstitial pneumonia pattern versus primary ARDS: a matched-control study

    Although patients with interstitial pneumonia pattern (ILD-UIP) and acute exacerbation (AE) leading to severe acute respiratory failure may require invasive mechanical ventilation (MV), physiological data on l...

    Roberto Tonelli, Salvatore Grasso, Andrea Cortegiani, Lorenzo Ball in Critical Care (2023)

  5. Article

    Reply to Letter response to “The Janus faces of SARS-COV-2 infection in myasthenia gravis and myasthenic crisis”

    Giuliana Galassi, Alessandro Marchioni in Neurological Sciences (2022)

  6. Article

    Comment on case series of COVID-19 in patients with myasthenia gravis: a single institution experience by Županić et al.

    Giuliana Galassi, Alessandro Marchioni in Acta Neurologica Belgica (2022)

  7. Article

    Open Access

    Nasal pressure swings as the measure of inspiratory effort in spontaneously breathing patients with de novo acute respiratory failure

    Excessive inspiratory effort could translate into self-inflicted lung injury, thus worsening clinical outcomes of spontaneously breathing patients with acute respiratory failure (ARF). Although esophageal mano...

    Roberto Tonelli, Andrea Cortegiani, Alessandro Marchioni, Riccardo Fantini in Critical Care (2022)

  8. Article

    Open Access

    Correction: Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia

    Pierluigi Donatelli, Fabiana Trentacosti in BMC Pulmonary Medicine (2022)

  9. Article

    Open Access

    Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia

    The main clinical consequences of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection are pneumonia and respiratory failure even requiring mechanical ventilation. In this context, the lung p...

    Pierluigi Donatelli, Fabiana Trentacosti in BMC Pulmonary Medicine (2021)

  10. Article

    Myasthenia gravis at the crossroad of COVID-19: focus on immunological and respiratory interplay

    Coronavirus disease 2019 (COVID-19), a disease caused by the novel betacoronavirus (SARS-CoV-2) has become a global pandemic threat. COVID-19 caused by SARS-CoV-2 is reported to originate in December 2019 in W...

    Giuliana Galassi, Alessandro Marchioni in Acta Neurologica Belgica (2021)

  11. Article

    Post-intubation tracheal stenosis in COVID-19 patients

    Francesco Mattioli, Alessandro Marchioni in European Archives of Oto-Rhino-Laryngology (2021)

  12. No Access

    Article

    Subclinical liver fibrosis in patients with idiopathic pulmonary fibrosis

    Data on the presence of subclinical fibrosis across multiple organs in patients with idiopathic lung fibrosis (IPF) are lacking. Our study aimed at investigating through hepatic transient elastography (HTE) th...

    Elisabetta Cocconcelli, Roberto Tonelli, Gianluca Abbati in Internal and Emergency Medicine (2021)

  13. No Access

    Article

    Predictors of respiratory decline in myotonic dystrophy type 1 (DM1): a longitudinal cohort study

    We studied 33 patients affected by juvenile and adult myotonic dystrophy type 1 (DM1). The aim of the study was to assess clinical and laboratory parameters that could predict the requirement of noninvasive ve...

    Marco Mazzoli, Alessandra Ariatti, Giancarlo Garuti in Acta Neurologica Belgica (2021)

  14. Article

    Facing acute neuromuscular diseases during COVID-19 pandemic: focus on Guillain–Barré syndrome

    In December 2019, a cluster of cases with 2019 Novel Coronavirus pneumonia from Wuhan, China, aroused worldwide concern due to an escalating outbreak in all the countries in the world. Coronavirus belongs to a...

    Giuliana Galassi, Alessandro Marchioni in Acta Neurologica Belgica (2020)

  15. Article

    Open Access

    Ventilatory support and mechanical properties of the fibrotic lung acting as a “squishy ball”

    Protective ventilation is the cornerstone of treatment of patients with the acute respiratory distress syndrome (ARDS); however, no studies have yet established the best ventilatory strategy to adopt when pati...

    Alessandro Marchioni, Roberto Tonelli, Giulio Rossi in Annals of Intensive Care (2020)

  16. Article

    Open Access

    Atypical diagnosis for typical lung carcinoid

    The diagnosis of lung typical carcinoid tumors results challenging when limited size and unfavorable sampling location is associated. It has been reported that bronchoscopy with endobronchial ultrasound (EBUS)...

    Roberto Piro, Roberto Tonelli, Sofia Taddei, Alessandro Marchioni in BMC Pulmonary Medicine (2019)

  17. Article

    Open Access

    Serial ultrasound assessment of diaphragmatic function and clinical outcome in patients with amyotrophic lateral sclerosis

    Diaphragmatic assessment by ultrasound (US) is a non-invasive and useful method in the clinical management of patients with Amyotrophic Lateral Sclerosis (ALS). The aim of our observational study was to evalua...

    Riccardo Fantini, Roberto Tonelli, Ivana Castaniere, Luca Tabbì in BMC Pulmonary Medicine (2019)

  18. Article

    Open Access

    An uncommon cause of hemoptysis: aortobronchial fistula

    Hemoptysis is a frequent sign of respiratory and non-respiratory diseases. While in most cases the underlying cause is rapidly identified, sometimes the real etiology might be misdiagnosed with dramatic delay ...

    Matteo Fontana, Roberto Tonelli, Filippo Gozzi in Multidisciplinary Respiratory Medicine (2018)

  19. Article

    Open Access

    Ultrasound-assessed diaphragmatic impairment is a predictor of outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease undergoing noninvasive ventilation

    Ultrasound (US) evaluation of diaphragmatic dysfunction (DD) has proved to be a reliable technique in critical care. In this single-center prospective study, we investigated the impact of US-assessed DD on non...

    Alessandro Marchioni, Ivana Castaniere, Roberto Tonelli, Riccardo Fantini in Critical Care (2018)

  20. Article

    Open Access

    Acute exacerbation of idiopathic pulmonary fibrosis: lessons learned from acute respiratory distress syndrome?

    Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease characterized by progressive loss of lung function and poor prognosis. The so-called acute exacerbation of IPF (AE-IPF) may lead to severe hypoxem...

    Alessandro Marchioni, Roberto Tonelli, Lorenzo Ball, Riccardo Fantini in Critical Care (2018)

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