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Open AccessStress–strain curve and elastic behavior of the fibrotic lung with usual interstitial pneumonia pattern during protective mechanical ventilation
Patients with acute exacerbation of lung fibrosis with usual interstitial pneumonia (EUIP) pattern are at increased risk for ventilator-induced lung injury (VILI) and mortality when exposed to mechanical venti...
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Effect of high flow nasal oxygen on inspiratory effort of patients with acute hypoxic respiratory failure and do not intubate orders
High flow nasal oxygen (HFNO) is recommended as a first-line respiratory support during acute hypoxic respiratory failure (AHRF) and represents a proportionate treatment option for patients with do not intubat...
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“Comment on Guillain Barre’ syndrome in children and adults in the north Iran by Hosseininezhad et al
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Open AccessPhysiological effects of lung-protective ventilation in patients with lung fibrosis and usual interstitial pneumonia pattern versus primary ARDS: a matched-control study
Although patients with interstitial pneumonia pattern (ILD-UIP) and acute exacerbation (AE) leading to severe acute respiratory failure may require invasive mechanical ventilation (MV), physiological data on l...
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Reply to Letter response to “The Janus faces of SARS-COV-2 infection in myasthenia gravis and myasthenic crisis”
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Comment on case series of COVID-19 in patients with myasthenia gravis: a single institution experience by Županić et al.
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Open AccessNasal pressure swings as the measure of inspiratory effort in spontaneously breathing patients with de novo acute respiratory failure
Excessive inspiratory effort could translate into self-inflicted lung injury, thus worsening clinical outcomes of spontaneously breathing patients with acute respiratory failure (ARF). Although esophageal mano...
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Open AccessCorrection: Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia
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Open AccessEndobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia
The main clinical consequences of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection are pneumonia and respiratory failure even requiring mechanical ventilation. In this context, the lung p...
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Myasthenia gravis at the crossroad of COVID-19: focus on immunological and respiratory interplay
Coronavirus disease 2019 (COVID-19), a disease caused by the novel betacoronavirus (SARS-CoV-2) has become a global pandemic threat. COVID-19 caused by SARS-CoV-2 is reported to originate in December 2019 in W...
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Post-intubation tracheal stenosis in COVID-19 patients
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Subclinical liver fibrosis in patients with idiopathic pulmonary fibrosis
Data on the presence of subclinical fibrosis across multiple organs in patients with idiopathic lung fibrosis (IPF) are lacking. Our study aimed at investigating through hepatic transient elastography (HTE) th...
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Predictors of respiratory decline in myotonic dystrophy type 1 (DM1): a longitudinal cohort study
We studied 33 patients affected by juvenile and adult myotonic dystrophy type 1 (DM1). The aim of the study was to assess clinical and laboratory parameters that could predict the requirement of noninvasive ve...
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Facing acute neuromuscular diseases during COVID-19 pandemic: focus on Guillain–Barré syndrome
In December 2019, a cluster of cases with 2019 Novel Coronavirus pneumonia from Wuhan, China, aroused worldwide concern due to an escalating outbreak in all the countries in the world. Coronavirus belongs to a...
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Open AccessVentilatory support and mechanical properties of the fibrotic lung acting as a “squishy ball”
Protective ventilation is the cornerstone of treatment of patients with the acute respiratory distress syndrome (ARDS); however, no studies have yet established the best ventilatory strategy to adopt when pati...
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Open AccessAtypical diagnosis for typical lung carcinoid
The diagnosis of lung typical carcinoid tumors results challenging when limited size and unfavorable sampling location is associated. It has been reported that bronchoscopy with endobronchial ultrasound (EBUS)...
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Open AccessSerial ultrasound assessment of diaphragmatic function and clinical outcome in patients with amyotrophic lateral sclerosis
Diaphragmatic assessment by ultrasound (US) is a non-invasive and useful method in the clinical management of patients with Amyotrophic Lateral Sclerosis (ALS). The aim of our observational study was to evalua...
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Open AccessAn uncommon cause of hemoptysis: aortobronchial fistula
Hemoptysis is a frequent sign of respiratory and non-respiratory diseases. While in most cases the underlying cause is rapidly identified, sometimes the real etiology might be misdiagnosed with dramatic delay ...
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Open AccessUltrasound-assessed diaphragmatic impairment is a predictor of outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease undergoing noninvasive ventilation
Ultrasound (US) evaluation of diaphragmatic dysfunction (DD) has proved to be a reliable technique in critical care. In this single-center prospective study, we investigated the impact of US-assessed DD on non...
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Open AccessAcute exacerbation of idiopathic pulmonary fibrosis: lessons learned from acute respiratory distress syndrome?
Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease characterized by progressive loss of lung function and poor prognosis. The so-called acute exacerbation of IPF (AE-IPF) may lead to severe hypoxem...