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Article
Open AccessTreatments for hearing loss in osteogenesis imperfecta: a systematic review and meta-analysis on their efficacy
About 70% of people with osteogenesis imperfecta (OI) experience hearing loss. There is no cure for OI, and therapies to ameliorate hearing loss rely on conventional treatments for auditory impairments in the ...
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Article
Poor bone matrix quality: What can be done about it?
Bone’s ability to withstand load resisting fracture and adapting to it highly depends on the quality of its matrix and its regulators. This review focuses on the contribution of bone quality to fracture resist...
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Chapter and Conference Paper
Optimizing User Experience in Amusement Parks and Enhancing Their Active Role in Urban Spaces Through New Technology
This paper intends to review the main technological innovations applied to the world of theme parks, with the aim of identifying the strategies that can be planned to guarantee visitors an optimized experience...
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Article
Open AccessTransient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response
Mechanoadaptation maintains bone mass and architecture; its failure underlies age-related decline in bone strength. It is unclear whether this is due to failure of osteocytes to sense strain, osteoblasts to fo...
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Article
Altered Bone Mechanics, Architecture and Composition in the Skeleton of TIMP-3-Deficient Mice
Tissue inhibitor of metalloproteinases-3 (TIMP-3) maintains a healthy extracellular matrix by regulating matrix metalloproteinases (MMP), disintegrin–metalloproteinases (ADAM), and disintegrin–metalloproteinas...
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Chapter and Conference Paper
Guidelines for Designing Accessible Digital (Text) Books: The Italian Case
In this paper, the authors analyze the state of the art of digital publishing, with particular attention towards what is going on in Italy, and investigate eBooks’ accessibility features, in order to understan...
