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Article
Open AccessEffect of Luseogliflozin, a Sodium-Glucose Cotransporter 2 Inhibitor, and Dipeptidyl-Peptidase 4 Inhibitors on the Quality-of-Life and Treatment Satisfaction of Patients With Type 2 Diabetes Mellitus: A Subanalysis of a Multicenter, Open-Label, Randomized-Controlled Trial (J-SELECT Study)
The effects of dipeptidyl peptidase-4 inhibitors (DPP-4is) and sodium-glucose cotransporter 2 inhibitors (SGLT2is) on quality of life (QOL) and treatment satisfaction have not been directly compared. This sub-...
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Article
Open AccessAnti-fatigue activity of methyl dihydrojasmonate and linalool in a rat model evaluated by a novel index for neuro-immune and oxidative stress interactions
Avoiding fatigue is a long-standing challenge in both healthy and diseased individuals. Establishing objective standard markers of fatigue is essential to evaluate conditions in spatiotemporally different loca...
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Chapter and Conference Paper
Superplasticity Deformation of Sn-Bi-Based Solder Alloys
alloys have drawn a large amount of attention. Because using low-temperature soldering also reduces the energy cost of fabrication . It allows the fabrication of inexpensive assembly , such as printed circu...
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Chapter
Root Plasticity for Adaptation and Productivity of Crop Plants Grown Under Various Water Stresses
Roots play significant functional roles in adaptation and productivity of crop plants especially when grown under various water stresses. The ability of plant to change its morphology as environmental conditio...
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Article
Open AccessOverall Efficacy and Safety of Sodium-Glucose Cotransporter 2 Inhibitor Luseogliflozin Versus Dipeptidyl-Peptidase 4 Inhibitors: Multicenter, Open-Label, Randomized-Controlled Trial (J-SELECT study)
Evidence of a direct comparison between dipeptidyl-peptidase 4 inhibitors (DPP-4is) and sodium-glucose cotransporter 2 inhibitors (SGLT2is) remains lacking, and no clear treatment strategy or rationale has bee...
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Article
Open AccessEstablishment of anti-DKK3 peptide for the cancer control in head and neck squamous cell carcinoma (HNSCC)
Head and neck squamous cell carcinoma (HNSCC) is the most common malignant tumor of the head and neck. We identified cancer-specific genes in HNSCC and focused on DKK3 expression. DKK3 gene codes two isoforms ...
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Article
Open AccessCorrection: QTL map** under salt stress in rice using a Kalarata–Azucena population
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Article
Open AccessQTL map** under salt stress in rice using a Kalarata–Azucena population
Salt stress is a major constraint across large rice production areas in Asia, because of the high sensitivity of modern rice varieties. To identify quantitative trait loci (QTL) associated with salt tolerance ...
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Article
Open AccessTissue-specific expression analysis of Na+ and Cl− transporter genes associated with salt removal ability in rice leaf sheath
A significant mechanism of salt-tolerance in rice is the ability to remove Na+ and Cl− in the leaf sheath, which limits the entry of these toxic ions into the leaf blade. The leaf sheath removes Na+ mainly in the...
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Article
Open AccessGenetic and clinical landscape of breast cancers with germline BRCA1/2 variants
The genetic and clinical characteristics of breast tumors with germline variants, including their association with biallelic inactivation through loss-of-heterozygosity (LOH) and second somatic mutations, rema...
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Article
Open AccessPlasticity in nodal root elongation through the hardpan triggered by rewatering during soil moisture fluctuation stress in rice
Rainfed lowland (RFL) rice fields have hardpans and experience soil moisture fluctuations (SMF) stress, which influence root system development. Here, we clarify the expression and timing of the plasticity in ...
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Chapter
Development of Rice Breeding and Cultivation Technology Tailored for Kenya’s Environment
In many sub-Saharan African countries, it is fundamental to boost rice production because the increased rice consumption exceeds the growth in domestic rice production. Kenya has currently implemented a policy...
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Article
Open AccessEvaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device
Migration of cancer cell correlates with distant metastasis and local invasion, which are good targets for cancer treatment. An optically accessible device “TAXIScan” was developed, which provides considerably...
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Article
Active Secretion of Dimerized S100A11 Induced by the Peroxisome in Mesothelioma Cells
S100A11, a small Ca2+ binding protein, acts extracellularly as a mediator of cancer progression. That raises the question of how a protein that lacks the classical secretory signal is able to be secreted outside ...
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Article
Evaluation of the effect of compression therapy using surgical gloves on nanoparticle albumin-bound paclitaxel-induced peripheral neuropathy: a phase II multicenter study by the Kamigata Breast Cancer Study Group
To investigate the efficacy of using surgical glove (SG) compression therapy to prevent nanoparticle albumin-bound paclitaxel (nab-PTX)-induced peripheral neuropathy.
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Article
Open AccessWell-defined polymer microspheres formed by living dispersion polymerization: precisely functionalized crosslinked polymer microspheres from monomers possessing cumulated double bonds
The precise method for synthesizing well-defined polymer microspheres via π-allylnickel-catalyzed living coordination polymerization of allene derivatives under dispersion polymerization conditions is describe...
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Article
MCAM, as a novel receptor for S100A8/A9, mediates progression of malignant melanoma through prominent activation of NF-κB and ROS formation upon ligand binding
The dynamic interaction between tumor cells and their microenvironment induces a proinflammatory milieu that drives cancer development and progression. The S100A8/A9 complex has been implicated in chronic infl...
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Article
QTL associated with lateral root plasticity in response to soil moisture fluctuation stress in rice
Lateral root (LR) plasticity is a key trait that plays a significant role in plant adaptation to fluctuating soil moisture stressed environments. We previously had demonstrated that promoted LR production (LR ...
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Article
Root plasticity and its functional roles were triggered by water deficit but not by the resulting changes in the forms of soil N in rice
The functional roles of root plasticity in rice adaptation to drought conditions may vary with soil nitrogen (N) conditions.
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Article
Prevalence and risk factors of bone metastasis and skeletal related events in patients with primary breast cancer in Japan
Bone metastasis (BM) is important for studying systemic spread of breast cancer. It often causes skeletal-related events (SREs) that worsen quality of life. We investigated the prevalence and risk factors for ...
