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Living Reference Work Entry In depth
Link Between the Immune System and Aggression
Evidence has shown links between aggression and the immune system in both humans and animal models, yet we know relatively little about the neuroimmune mechanisms involved. In animals, dominant/aggressive indi...
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Reference Work Entry In depth
Link Between the Immune System and Aggression
Evidence has shown links between aggression and the immune system in both humans and animal models, yet we know relatively little about the neuroimmune mechanisms involved. In animals, dominant/aggressive indi...
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Article
Open AccessLateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice
The dorsal raphe nucleus (DRN) is known to control aggressive behavior in mice. Here, we found that glutamatergic projections from the lateral habenula (LHb) to the DRN were activated in male mice that experie...
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Article
Neuromodulatory effect of interleukin 1β in the dorsal raphe nucleus on individual differences in aggression
Heightened aggressive behavior is considered as one of the central symptoms of many neuropsychiatric disorders including autism, schizophrenia, and dementia. The consequences of aggression pose a heavy burden ...
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Chapter
Social Stress and Aggression in Murine Models
Throughout life, animals engage in a variety of social interactions ranging from the affiliative mother–offspring interaction and juvenile play to aggressive conflict. Deprivation of the appropriate social int...
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Article
Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice
Heightened aggression is characteristic of multiple neuropsychiatric disorders and can have various negative effects on patients, their families and the public. Recent studies in humans and animals have implic...
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Article
Combinatorial Psycho-Pharmacological Approaches for the Treatment of Abnormal Aggression
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Article
Social stress induces neurovascular pathology promoting depression
Studies suggest that heightened peripheral inflammation contributes to the pathogenesis of major depressive disorder. We investigated the effect of chronic social defeat stress, a mouse model of depression, on...
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Article
Open AccessEstablishment of a repeated social defeat stress model in female mice
Numerous studies have employed repeated social defeat stress (RSDS) to study the neurobiological mechanisms of depression in rodents. An important limitation of RSDS studies to date is that they have been cond...
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Article
Open AccessHierarchy in the home cage affects behaviour and gene expression in group-housed C57BL/6 male mice
Group-housed male mice exhibit aggressive behaviour towards their cage mates and form a social hierarchy. Here, we describe how social hierarchy in standard group-housed conditions affects behaviour and gene e...
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Protocol
Automated Estimation of Mouse Social Behaviors Based on a Hidden Markov Model
Recent innovations in sensing and Information and Communication Technology (ICT) have enabled researchers in animal behavior to collect an enormous amount of data. Consequently, the development of an automated...
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Article
α2-containing GABA(A) receptors: a requirement for midazolam-escalated aggression and social approach in mice
Benzodiazepines (BZDs) are prescribed to reduce anxiety, agitation, and muscle spasms and for their sedative-hypnotic and anticonvulsant effects. Under specific conditions, BZDs escalate aggression in some ind...
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Chapter
Neurogenetics of Aggressive Behavior: Studies in Rodents
Aggressive behavior is observed in many animal species, such as insects, fish, lizards, frogs, and most mammals including humans. This wide range of conservation underscores the importance of aggressive behavi...
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Article
Ectopic pregnancy: MRI findings and clinical utility
To assess the utility of magnetic resonance imaging (MRI) in patients with clinically suspected ectopic pregnancy (EP).
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Article
Behavioral characterization of escalated aggression induced by GABAB receptor activation in the dorsal raphe nucleus
Pharmacological activation of GABAB receptors in the dorsal raphe nucleus (DRN) can escalate territorial aggression in male mice.
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Article
NMDA receptor antagonism: escalation of aggressive behavior in alcohol-drinking mice
Memantine is a potential treatment for alcoholic patients, yet few studies investigate the effect of concurrent treatment with memantine and ethanol on aggression. We evaluated aggressive behavior following et...
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Chapter
Behavioral and Pharmacogenetics of Aggressive Behavior
Serotonin (5-HT) has long been considered as a key transmitter in the neurocircuitry controlling aggression. Impaired regulation of each subtype of 5-HT receptor, 5-HT transporter, synthetic and metabolic enzy...
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Article
Gene Expression in Aminergic and Peptidergic Cells During Aggression and Defeat: Relevance to Violence, Depression and Drug Abuse
In this review, we examine how experiences in social confrontations alter gene expression in mesocorticolimbic cells. The focus is on the target of attack and threat due to the prominent role of social defeat ...
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Article
B6-MSM Consomic Mouse Strains Reveal Multiple Loci for Genetic Variation in Sucrose Octaacetate Aversion
Based on crosses among inbred strains derived principally from M. m. domesticus, sucrose octaacetate (SOA) aversion in laboratory mice has been thought for many years to be controlled by a single genetic locus (S...
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Article
Retained placental tissue: role of MRI findings in diagnosis and clinical assessment
To assess the role of MRI in diagnosis and predicting clinical outcome in women with retained placental tissue.
