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Article
A BAC clone of MDV strain GX0101 with REV-LTR integration retained its pathogenicity
The complete genome of Marek’s disease virus (MDV) strain GX0101, which was integrated with the LTR sequences of REV, was cloned in Escherichia coli as a bacterial artificial chromosome (BAC). BAC vector sequence...
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Article
Open AccessHydrogen Sulfide Attenuates the Recruitment of CD11b+Gr-1+ Myeloid Cells and Regulates Bax/Bcl-2 Signaling in Myocardial Ischemia Injury
Hydrogen sulfide, an endogenous signaling molecule, plays an important role in the physiology and pathophysiology of the cardiovascular system. Using a mouse model of myocardial infarction, we investigated the...
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Article
Open AccessThe histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction
Myocardial infarction (MI) dampens heart function and poses a great health risk. The class III deacetylase sirtuin 1 (SIRT1) is known to confer cardioprotection. SIRT1 expression is downregulated in the heart ...
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Article
Open AccessComprehensive profiling analysis of the N6-methyladenosine-modified circular RNA transcriptome in cultured cells infected with Marek’s disease virus
Marek’s disease virus (MDV) induces severe immunosuppression and lymphomagenesis in the chicken, its natural host, and results in a condition that investigated the pathogenesis of MDV and have begun to focus o...
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Article
Open AccessGPR174 knockdown enhances blood flow recovery in hindlimb ischemia mice model by upregulating AREG expression
Regulatory T cells (Tregs) are critically involved in neovascularization, an important compensatory mechanism in peripheral artery disease. The contribution of G protein coupled receptor 174 (GPR174), which is...
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Article
Open AccessCuproptosis-related genes predict prognosis and trastuzumab therapeutic response in HER2-positive breast cancer
Breast cancer is the most common diagnosed cancer, the HER2-positive subtype account for 15% of all breast cancer. HER2-targeted therapy is the mainstay treatment for HER2-positive breast cancer. Cuproptosis i...
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Article
Open AccessAuthor Correction: Cuproptosis-related genes predict prognosis and trastuzumab therapeutic response in HER2-positive breast cancer