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    Article

    A BAC clone of MDV strain GX0101 with REV-LTR integration retained its pathogenicity

    The complete genome of Marek’s disease virus (MDV) strain GX0101, which was integrated with the LTR sequences of REV, was cloned in Escherichia coli as a bacterial artificial chromosome (BAC). BAC vector sequence...

    AiJun Sun, Petherbridge Lawrence, YuGuang Zhao, YanPeng Li in Chinese Science Bulletin (2009)

  2. Article

    Open Access

    Hydrogen Sulfide Attenuates the Recruitment of CD11b+Gr-1+ Myeloid Cells and Regulates Bax/Bcl-2 Signaling in Myocardial Ischemia Injury

    Hydrogen sulfide, an endogenous signaling molecule, plays an important role in the physiology and pathophysiology of the cardiovascular system. Using a mouse model of myocardial infarction, we investigated the...

    Youen Zhang, Hua Li, Gang Zhao, Aijun Sun, Nobel C. Zong, Zhaofeng Li in Scientific Reports (2014)

  3. Article

    Open Access

    The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction

    Myocardial infarction (MI) dampens heart function and poses a great health risk. The class III deacetylase sirtuin 1 (SIRT1) is known to confer cardioprotection. SIRT1 expression is downregulated in the heart ...

    Guang Yang, **nyu Weng, Yuhao Zhao, **njian Zhang, Yuan** Hu in Nature Communications (2017)

  4. Article

    Open Access

    Comprehensive profiling analysis of the N6-methyladenosine-modified circular RNA transcriptome in cultured cells infected with Marek’s disease virus

    Marek’s disease virus (MDV) induces severe immunosuppression and lymphomagenesis in the chicken, its natural host, and results in a condition that investigated the pathogenesis of MDV and have begun to focus o...

    Aijun Sun, Rui Wang, Shuaikang Yang, **ao**g Zhu, Ying Liu, Man Teng in Scientific Reports (2021)

  5. Article

    Open Access

    GPR174 knockdown enhances blood flow recovery in hindlimb ischemia mice model by upregulating AREG expression

    Regulatory T cells (Tregs) are critically involved in neovascularization, an important compensatory mechanism in peripheral artery disease. The contribution of G protein coupled receptor 174 (GPR174), which is...

    ** Liu, Lihong Pan, Wenxuan Hong, Siqin Chen, Peiyuan Bai in Nature Communications (2022)

  6. Article

    Open Access

    Cuproptosis-related genes predict prognosis and trastuzumab therapeutic response in HER2-positive breast cancer

    Breast cancer is the most common diagnosed cancer, the HER2-positive subtype account for 15% of all breast cancer. HER2-targeted therapy is the mainstay treatment for HER2-positive breast cancer. Cuproptosis i...

    Rui Sha, **nrui Dong, Shanshan Yan, Huijuan Dai, Aijun Sun in Scientific Reports (2024)

  7. Article

    Open Access

    Author Correction: Cuproptosis-related genes predict prognosis and trastuzumab therapeutic response in HER2-positive breast cancer

    Rui Sha, **nrui Dong, Shanshan Yan, Huijuan Dai, Aijun Sun in Scientific Reports (2024)