67 Result(s)

Article

Author Correction: Cuproptosis-related genes predict prognosis and trastuzumab therapeutic response in HER2-positive breast cancer

Rui Sha, **nrui Dong, Shanshan Yan, Huijuan Dai, Aijun Sun… in Scientific Reports (2024)

Article

TEA domain transcription factor 1 (TEAD1) induces cardiac fibroblasts cells remodeling through BRD4/Wnt4 pathway

Cardiac fibroblasts (CFs) are the primary cells tasked with depositing and remodeling collagen and significantly associated with heart failure (HF). TEAD1 has been shown to be essential for heart development a...

Shuai Song, **aokai Zhang, Zihang Huang… in Signal Transduction and Targeted Therapy (2024)

Article

Cuproptosis-related genes predict prognosis and trastuzumab therapeutic response in HER2-positive breast cancer

Breast cancer is the most common diagnosed cancer, the HER2-positive subtype account for 15% of all breast cancer. HER2-targeted therapy is the mainstay treatment for HER2-positive breast cancer. Cuproptosis i...

Rui Sha, **nrui Dong, Shanshan Yan, Huijuan Dai, Aijun Sun… in Scientific Reports (2024)

Article

Gut microbe-derived metabolite indole-3-carboxaldehyde alleviates atherosclerosis

Yi**g Lu, Wenlong Yang, Zhiyong Qi, Rifeng Gao… in Signal Transduction and Targeted Therapy (2023)

Article

Dingkun pill alleviates metabolic abnormalities in polycystic ovary syndrome through brown adipose tissue activation

Traditional Chinese medicine has been used for a long time to treat a variety of gynecological diseases. Among various traditional Chinese medicine, Dingkun Pill (DK) has been used for the treatment of female ...

Mengqing Gu, Han Cai, Weinan Deng, Yedong Tang, Shuailin Du… in Journal of Ovarian Research (2023)

Article

An international multidisciplinary consensus statement on MAFLD and the risk of CVD

Fatty liver disease in the absence of excessive alcohol consumption is an increasingly common condition with a global prevalence of ~ 25–30% and is also associated with cardiovascular disease (CVD). Since syst...

**ao-Dong Zhou, Giovanni Targher, Christopher D. Byrne… in Hepatology International (2023)

Article

GPR174 knockdown enhances blood flow recovery in hindlimb ischemia mice model by upregulating AREG expression

Regulatory T cells (Tregs) are critically involved in neovascularization, an important compensatory mechanism in peripheral artery disease. The contribution of G protein coupled receptor 174 (GPR174), which is...

** Liu, Lihong Pan, Wenxuan Hong, Siqin Chen, Peiyuan Bai… in Nature Communications (2022)

Article

Correction to: Gasdermin D mediates endoplasmic reticulum stress via FAM134B to regulate cardiomyocyte autophagy and apoptosis in doxorubicin-induced cardiotoxicity

Ya’nan Qu, Rifeng Gao, **ang Wei, **aolei Sun, Kun Yang… in Cell Death & Disease (2022)

Article

Gasdermin D mediates endoplasmic reticulum stress via FAM134B to regulate cardiomyocyte autophagy and apoptosis in doxorubicin-induced cardiotoxicity

Cardiomyocyte pyroptosis and apoptosis play a vital role in the pathophysiology of several cardiovascular diseases. Our recent study revealed that gasdermin D (GSDMD) can promote myocardial I/R injury via the ...

Ya’nan Qu, Rifeng Gao, **ang Wei, **aolei Sun, Kun Yang… in Cell Death & Disease (2022)

Article

Effects of the ketogenic diet in mice with hind limb ischemia

The ketogenic diet (KD) has anti-tumor and anti-diabetic effects in addition to its anti-epileptic role. It could also improve cardiac function and attenuate neurological insult. However, the effect of KD on b...

Adilan Shalamu, Zhen Dong, Bowen Liu, Lihong Pan, Yun Cai… in Nutrition & Metabolism (2022)

Article

β-Hydroxybutyrate Exacerbates Hypoxic Injury by Inhibiting HIF-1α-Dependent Glycolysis in Cardiomyocytes—Adding Fuel to the Fire?

Ketone body oxidation yields more ATP per mole of consumed oxygen than glucose. However, whether an increased ketone body supply in hypoxic cardiomyocytes and ischemic hearts is protective or not remains elusi...

**urui Ma, Zhen Dong, **gyi Liu, Leilei Ma… in Cardiovascular Drugs and Therapy (2022)

Article

Comparative evaluation of low-level light therapy and ethinyl estradiol and desogestrel combined oral contraceptive for clinical efficacy and regulation of serum biochemical parameters in primary dysmenorrhoea: a prospective randomised multicentre trial

We aimed to compare low-level light therapy with oral contraceptive pills for pain relief and serum levels of nitric oxide and prostaglandin E₂ in patients with primary dysmenorrhoea. This was a randomised, activ...

Shiyang Zhu, **ao Ma, Xuesong Ding, **gwen Gan, Yan Deng… in Lasers in Medical Science (2022)

Article

m6A demethylase FTO attenuates cardiac dysfunction by regulating glucose uptake and glycolysis in mice with pressure overload-induced heart failure

Beijian Zhang, Hao Jiang, Jian Wu, Yun Cai… in Signal Transduction and Targeted Therapy (2021)

Article

Origin and Spread of the ALDH2 Glu504Lys Allele

Gene polymorphism of acetaldehyde dehydrogenase 2 (ALDH2), a key enzyme for alcohol metabolism in humans, can affect catalytic activity. The ALDH2 Glu504Lys mutant allele has a high-frequency distribution in E...

**aokai Zhang, Aijun Sun, Junbo Ge in Phenomics (2021)

Article

Obesity management in polycystic ovary syndrome: disparity in knowledge between obstetrician-gynecologists and reproductive endocrinologists in China

Obesity is associated with the development of polycystic ovary syndrome (PCOS) and contributes substantially to metabolic abnormalities in women with PCOS. The study aimed to describe and compare the practices...

Ruilin Ma, Ying Zou, Wei Wang, Qingmei Zheng, Ying Feng… in BMC Endocrine Disorders (2021)

Article

Comprehensive profiling analysis of the N6-methyladenosine-modified circular RNA transcriptome in cultured cells infected with Marek’s disease virus

Marek’s disease virus (MDV) induces severe immunosuppression and lymphomagenesis in the chicken, its natural host, and results in a condition that investigated the pathogenesis of MDV and have begun to focus o...

Aijun Sun, Rui Wang, Shuaikang Yang, **ao**g Zhu, Ying Liu, Man Teng… in Scientific Reports (2021)

Article

Transcriptome-wide N6-methyladenosine modification profiling of long non-coding RNAs during replication of Marek’s disease virus in vitro

The newly discovered reversible N6-methyladenosine (m⁶A) modification plays an important regulatory role in gene expression. Long non-coding RNAs (lncRNAs) participate in Marek’s disease virus (MDV) replication b...

Aijun Sun, **ao**g Zhu, Ying Liu, Rui Wang, Shuaikang Yang, Man Teng… in BMC Genomics (2021)