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  1. No Access

    Article

    Down-Regulation of Inwardly Rectifying Kir2.1 K+ Channels by Human Parvovirus B19 Capsid Protein VP1

    Parvovirus B19 (B19V) has previously been shown to cause endothelial dysfunction. B19V capsid protein VP1 harbors a lysophosphatidylcholine producing phospholipase A2 (PLA2). Lysophosphatidylcholine inhibits Na+/...

    Musaab Ahmed, Bernat Elvira, Ahmad Almilaji… in The Journal of Membrane Biology (2015)

  2. No Access

    Article

    Up-regulation of Kv1.3 Channels by Janus Kinase 2

    The janus-activated kinase 2 JAK2 participates in the signalling of several hormones including interferon, a powerful regulator of lymphocyte function. Lymphocyte activity and survival depend on the activity ...

    Zohreh Hosseinzadeh, Jamshed Warsi, Bernat Elvira… in The Journal of Membrane Biology (2015)

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    Article

    AMP-activated protein kinase regulates hERG potassium channel

    Besides their role in cardiac repolarization, human ether-a-go-go-related gene potassium (hERG) channels are expressed in several tumor cells including rhabdomyosarcoma cells. The channels foster cell prolifer...

    Ahmad Almilaji, Carlos Munoz, Bernat Elvira… in Pflügers Archiv - European Journal of Phys… (2013)

  4. No Access

    Article

    Up-Regulation of the Inwardly Rectifying K+ Channel Kir2.1 (KCNJ2) by Protein Kinase B (PKB/Akt) and PIKfyve

    The inward rectifier K+ channel Kir2.1 contributes to the maintenance of the resting cell membrane potential in excitable cells. Loss of function mutations of KCNJ2 encoding Kir2.1 result in Andersen-Tawil syndro...

    Carlos Munoz, Ahmad Almilaji, Iwan Setiawan… in The Journal of Membrane Biology (2013)

  5. No Access

    Article

    Downregulation of the renal outer medullary K+ channel ROMK by the AMP-activated protein kinase

    The 5′-adenosine monophosphate-activated serine/threonine protein kinase (AMPK) is stimulated by energy depletion, increase in cytosolic Ca2+ activity, oxidative stress, and nitric oxide. AMPK participates in the...

    Balasaheb Siraskar, Dan Yang Huang… in Pflügers Archiv - European Journal of Phys… (2013)