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  1. Article

    Open Access

    Cellular stress induces erythrocyte assembly on intravascular von Willebrand factor strings and promotes microangiopathy

    Microangiopathy with subsequent organ damage represents a major complication in several diseases. The mechanisms leading to microvascular occlusion include von Willebrand factor (VWF), notably the formation of...

    Jan P. Nicolay, Verena Thorn, Christoph Daniel, Kerstin Amann… in Scientific Reports (2018)

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    Article

    Downregulation of the renal outer medullary K+ channel ROMK by the AMP-activated protein kinase

    The 5′-adenosine monophosphate-activated serine/threonine protein kinase (AMPK) is stimulated by energy depletion, increase in cytosolic Ca2+ activity, oxidative stress, and nitric oxide. AMPK participates in the...

    Balasaheb Siraskar, Dan Yang Huang… in Pflügers Archiv - European Journal of Phys… (2013)

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    Article

    Enhanced catecholamine release in mice expressing PKB/SGK-resistant GSK3

    Glycogen synthase kinase 3 (GSK3) plays a decisive role in the regulation of multiple functions. GSK3 is phosphorylated and its activity inhibited by protein kinase B (PKB/Akt) and serum and glucocorticoid ind...

    Balasaheb Siraskar, Jakob Völkl… in Pflügers Archiv - European Journal of Phys… (2011)