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Article
Open AccessThe impact of hepatic and splenic volumetric assessment in imaging for chronic liver disease: a narrative review
Chronic liver disease is responsible for significant morbidity and mortality worldwide. Abdominal computed tomography (CT) and magnetic resonance imaging (MRI) can fully visualise the liver and adjacent struct...
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Article
A Single Centre Experience with Pre-Operative Markers in the Prediction of Outcomes after Liver Resection for Hepatocellular Carcinoma
The C-reactive protein to albumin ratio, albumin-bilirubin index and platelet-albumin-bilirubin index have emerged as prognostic scores in hepatocellular carcinoma, although their clinical utility remains uncl...
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Article
Open AccessClinical and financial impacts of abnormal liver biochemistry after liver transplantation
After liver transplant (LT), many investigations are needed to evaluate abnormal liver function test (LFT), which has poor specificity for graft function and complication. A single center retrospective audit of a...
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Article
Determining Energy Requirements in Cirrhosis: an Update on the Role of Indirect Calorimetry
Malnutrition in cirrhosis is associated with significant morbidity and mortality, and an accurate energy prescription is central to effective nutrition therapy. Indirect calorimetry is recommended to determine...
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Article
Open AccessUtility and limitations of Hepascore and transient elastography to detect advanced hepatic fibrosis in HFE hemochromatosis
Aspartate aminotransferase-to-platelet ratio index (APRI) and Fibrosis-4 Index (Fib4) have been validated against liver biopsy for detecting advanced hepatic fibrosis in HFE hemochromatosis. We determined the ...
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Article
Comment on: “Hypoxia differently modulates the release of mitochondrial and nuclear DNA”
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Article
Quantitation and chemical coding of enteroendocrine cell populations in the human jejunum
Recent studies reveal substantial species and regional differences in enteroendocrine cell (EEC) populations, including differences in patterns of hormone coexpression, which limit extrapolation between animal...
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Article
Glucagon-like peptide 1 and peptide YY are in separate storage organelles in enteroendocrine cells
A sub-group of enteroendocrine cells (L cells) release gastrointestinal hormones, GLP-1 and PYY, which have different but overlap** physiological effects, in response to intraluminal nutrients. Whilst their ...
