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Open AccessLong-term outcome of patients with newly diagnosed chronic myeloid leukemia: a randomized comparison of stem cell transplantation with drug treatment
Tyrosine kinase inhibitors represent today’s treatment of choice in chronic myeloid leukemia (CML). Allogeneic hematopoietic stem cell transplantation (HSCT) is regarded as salvage therapy. This prospective ra...
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Article
Reply to Ø Bruserud: Increases of sICAM-1 in neutropenic fever
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Article
Increases of sICAM-1 during neutropenic pneumonia in leukemic patients
Aggressive chemotherapy of leukemia increases the risk of severe infections during treatment-induced myelosuppression. However, the assessment of an infectious origin of neutropenic fever is often difficult. L...
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Article
Pulmonary toxicity during infusion of liposomal amphotericin B in two patients with acute leukemia
Pulmonary toxicity with acute dyspnea occurred during infusion of a liposomal amphotericin B preparation (AmBisome) in two adult leukemic patients. The preparation was administered as a one hour infusion at a ...
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Article
Influence of splenectomy on platelet morphometry and function
Functional and morphometric platelet abnormalities may be influenced by splenectomy and thus contribute to postoperative thrombohaemorrhagic complications, especially in patients with splenomegaly and/or plate...
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Article
Platelet volume parameters as a diagnostic tool: The influence of anticoagulation and storage conditions on platelet impedance volume
Rapid progress has been made in the design of aperture impedance cell counters, and parameters such as mean platelet volume and platelet distribution width have become routinely available to most physicians. P...
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Article
Polychemotherapy of acute myelogenous leukemia in a patient with acute intermittent porphyria
The safety of drugs in hepatic porphyrias has largely been established by clinical experience, which is very limited in the case of antineoplastic agents. We administered three cycles of polychemotherapy consi...
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Article
Thrombotic and hemorrhagic tendency in patients with malignant disease