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  1. No Access

    Article

    Three-Dimensional Structure of the Triple Mutant DiB3-F53L/F74L/L129M of the Fluorescent Complex of Bacterial Lipocalin with a Chromophore

    Objective: In the development of biomarker systems for cell biology, Blc lipocalin proved to be a promising scaffold for binding the fluorogen M739. This work presents the results of the molecular dynamics study ...

    A. V. Rossokhin, E. A. Goryacheva… in Russian Journal of Bioorganic Chemistry (2024)

  2. No Access

    Article

    Alternative Chromophore Binding Sites in Noncovalent Fluorescent Complexes of Bacterial Lipocalin

    The three-dimensional structure of DiB3, a fluorescent noncovalent complex of a genetically engineered variant of the bacterial protein lipocalin Blc with the synthetic GFP-like chromophore M739, was determine...

    E. A. Goryacheva, I. V. Artem’ev… in Russian Journal of Bioorganic Chemistry (2023)

  3. No Access

    Article

    Homology modeling of the transmembrane domain of the GABAA receptor

    The permeability of ion channels for ions and substances that bind inside the pore depends on the cross-sectional area of the pore. We have constructed models of the closed, open, and desensitized α1β2γ2 GABAA re...

    A. V. Rossokhin in Biophysics (2017)

  4. No Access

    Article

    SOD1 gene mutations in patients with amyotrophic lateral sclerosis: Potential of method of molecular modeling

    Molecular modeling is a promising method for assessing protein structures that is capable of presenting an energetically beneficial protein conformation with atomic precision. This method is of great importanc...

    E. V. Lysogorskaia, A. V. Rossokhin, N. Yu. Abramycheva… in Molecular Biology (2013)

  5. No Access

    Article

    Intracellular studies of the interaction between paired-pulse facilitation and the delayed phase of long-term potentiation in the hippocampus

    The mechanisms of the early (up to 1 h) and late (up to 3 h) phases of long-term potentiation were studied by analyzing the interaction between long-term potentiation and presynaptic paired-pulse facilitation....

    L. L. Voronin, A. V. Rossokhin, M. V. Sokolov in Neuroscience and Behavioral Physiology (1999)