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Article
Open AccessRepeatability of quantitative 18F-FLT uptake measurements in solid tumors: an individual patient data multi-center meta-analysis
3′-deoxy-3′-[18F]fluorothymidine (18F–FLT) positron emission tomography (PET) provides a non-invasive method to assess cellular proliferation and response to antitumor therapy. Quantitative 18F–FLT uptake metrics...
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Article
Open AccessImplementing diffusion-weighted MRI for body imaging in prospective multicentre trials: current considerations and future perspectives
For body imaging, diffusion-weighted MRI may be used for tumour detection, staging, prognostic information, assessing response and follow-up. Disease detection and staging involve qualitative, subjective asses...
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Article
Open AccessOxygen-enhanced MRI can accurately identify, quantify and map tumour hypoxia in preclinical models
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Article
Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging
Many therapeutic approaches to cancer affect the tumour vasculature, either indirectly or as a direct target. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has become an important means of inv...
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Chapter and Conference Paper
Quantifying Heterogeneity in Dynamic Contrast-Enhanced MRI Parameter Maps
Simple summary statistics of Dynamic Contrast-Enhanced MRI (DCE-MRI) parameter maps (e.g. the median) neglect the spatial arrangement of parameters, which appears to carry important diagnostic and prognostic i...
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Article
High-resolution magnetic resonance and volume rendering of the labyrinth
Our aim was to verify the feasibility of volume rendering (VR) of high-resolution magnetic resonance (HR-MR) data sets of the labyrinth. We retrospectively reviewed the HR-MR data sets of 16 consecutive patie...
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Article
Use of single-slice thick slab phase-contrast angiography for the diagnosis of dural venous sinus thrombosis
The aim of this study was to examine the reliability of single-slice phase-contrast angiography (SSPCA) as a rapid technique for the investigation of suspected dural venous sinus occlusion. Images were obtain...
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Article
Demonstration of cerebral perfusion abnormalities in moyamoya disease using susceptibility perfusion- and diffusion-weighted MRI
We describe the use of diffusion-weighted imaging and perfusion MRI using a contrast-medium bolus in the preoperative investigation for young man presenting with a cerebral ischaemic episode as a manifestatio...
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Chapter and Conference Paper
Locating Motion Artifacts in Parametric fMRI Analysis
In this paper we assess rigid body co-registration in terms of residual motion artifacts for the different correlation approaches used in fMRI. We summarise, from a statistical perspective, the three main appr...
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Article
The callosal-septal interface lesion in multiple sclerosis: effect of sequence and imaging plane
We examined the effect of imaging plane and sequence on the demonstration of lesions at the callosalseptal interface (CSI) by magnetic resonance imaging in 20 patients with known multiple sclerosis. Variable-e...
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Article
Measurement of orbital volumes following trauma using low-dose computed tomography
We describe a simple CT technique for the assessment of enophthalmos and measurement of orbital volumes following trauma. The technique uses original diagnostic CT images, standard CT software and involves no ...
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Article
CT appearances of haematomas in the corpus callosum in patients with subarachnoid haemorrhage
Corpus callosum heamatoma is a rare feature in subarachnoid haemorrhage (SAH), which may result from aneurysms of the anterior communicating artery (ACoA) or pericallosal artery (PCA). In 348 patients with ane...