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Article
Open AccessProperties of non-coding mutation hotspots as urinary biomarkers for bladder cancer detection
Mutations at specific hotspots in non-coding regions of ADGRG6, PLEKHS1, WDR74, TBC1D12 and LEPROTL1 frequently occur in bladder cancer (BC). These mutations could function as biomarkers for the non-invasive dete...
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Chapter and Conference Paper
An Ergonomic Perspective of Uttarakhand Weavers
The study of the relationship shared between man, machine and environment is known as ergonomics. One of the most widely established cottage industry of India is handloom. In the early days, weaving was just a...
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Article
Evaluation of biliary ductal anatomy in potential living liver donors: comparison between MRCP and Gd-EOB-DTPA-enhanced MRI
To compare magnetic resonance cholangiopancreatography (MRCP) and Gd-EOB-DTPA-enhanced MRI in the evaluation of the biliary anatomy in potential living liver donors (LLDs).
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Article
Liver failure determines the outcome in patients of acute-on-chronic liver failure (ACLF): comparison of APASL ACLF research consortium (AARC) and CLIF-SOFA models
Acute-on-chronic liver failure (ACLF) is a progressive disease associated with rapid clinical worsening and high mortality. Early prediction of mortality and intervention can improve patient outcomes. We aimed...
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Article
Open AccessMethylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer
Stage II colon cancer (CC) still remains a clinical challenge with patient stratification for adjuvant therapy (AT) largely relying on clinical parameters. Prognostic biomarkers are urgently needed for better ...
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Article
Signature effects in Gallagher-Moszkowski doublets of doubly odd 162, 164Ho and 164Tm nuclei
The signature effects in total five Gallagher-Moszkowski (GM) doublets, three based on the \( K^{\pi} = 1^{-}\) ( ↑ ↓ )...
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Article
Signature splitting in two quasiparticle rotational bands of 180,182Ta
The signature splittings in K π = 1 +: 7 /2[404] π ⊗9 /2[624] ν , K ...
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Article
Quantification of hydration products in cementitious materials incorporating silica nanoparticles
In the present work, silica nanoparticles (30-70nm) were supplemented into cement paste to study their influence on degree of hydration, porosity and formation of different type of calcium-silicate-hydrate (C-...
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Article
Open AccessA quality improvement comparative audit on theimpact of competency based basic intensive care medicine (ICM) training on the confidence levels of medical senior house officers registrars dealing with intensive care procedures in acutely ill patients
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Article
Open AccessMiR-320e is a novel prognostic biomarker in colorectal cancer
Advances in early detection and treatment have improved outcomes in patients with colorectal cancer (CRC). However, there remains a need for robust prognostic and predictive biomarkers. We conducted a systemat...
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Article
Open AccessmiR-542-3p suppresses osteoblast cell proliferation and differentiation, targets BMP-7 signaling and inhibits bone formation
MicroRNAs (miRNAs) are short non-coding RNAs that interfere with translation of specific target mRNAs and thereby regulate diverse biological processes. Recent studies have suggested that miRNAs might have a r...
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Article
Fortschritte bei der Eliminierung von Masern und Röteln in der Europäischen Region der WHO
In der Europäischen Region der Weltgesundheitsorganisation (WHO) wurden bedeutende Fortschritte hin zum Erreichen des Ziels der Masern- und Rötelneliminierung gemacht. Im vorliegenden Beitrag werden Surveillan...
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Article
Selective estrogen receptor modulators for BPH: new factors on the ground
As the current management of BPH/lower urinary tract symptoms by traditionally involved pharmacological agents such as 5alpha-reductase inhibitors and α1-adrenoceptor antagonists is suboptimal, there is definite ...
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Article
Joint ICI Cancellation and PAPR Reduction in OFDM Systems Without Side Information
Intercarrier interference (ICI) self-cancellation, new ICI self-cancellation and conjugate cancellation schemes have been proposed in the literature to mitigate the effect of ICI. In this paper we have perform...
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Article
Frailty is associated with longer hospital stay and increased mortality in hospitalized older patients
With the onset of frailty, there is often a rapid, progressive, and self-perpetuating downward spiral towards death. Frailty has enormous impact on acute hospital care and has been shown to be a more effective...
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Article
Open AccessDAMTC regulates cytoskeletal reorganization and cell motility in human lung adenocarcinoma cell line: an integrated proteomics and transcriptomics approach
DAMTC (7,8-diacetoxy-4-methylcoumarin) is a thioderivative of 4-methyl coumarin, and previously we have shown that DAMTC is a potent inhibitor of cell growth and an inducer of apoptosis in non-small cell lung ...
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Article
Detection of Rotavirus from Hospitalized Diarrheic Children in Uttar Pradesh, India
In the present study 220 stool samples collected from diarrheic children admitted to different hospitals and nursing homes of Uttar Pradesh and Uttarakhand were screened for rotavirus. Of 220 diarrheic samples...
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Article
Premature T cell senescence in Ovx mice is inhibited by repletion of estrogen and medicarpin: a possible mechanism for alleviating bone loss
Presently the relationship between CD28, biological marker of senescence, and ovariectomy is not well understood. We show that ovariectomy leads to CD28 loss on T cells and estrogen (E2) repletion and medicarp...
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Chapter
Synthesis of Colloidal Iridium Nanoparticles and Their Role as Catalyst in Homogeneous Catalysis – An Approach to Green Chemistry
The formation of colloidal iridium nanoparticles has been carried out by the chemical reduction of H2IrCl6 with methanol using polyvinyl-pyrrolidone as protecting agent. The synthesized iridium nanoparticles were...
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Article
Effect of Gastric Lavage in Preventing Feeding Problems in Late Preterm and Term Neonates Born with Meconium Stained Amniotic Fluid : A Randomized Controlled Trial
Background: It is a routine practice in many hospitals to perform gastric lavage in babies born with meconium stained amniotic fluid. But there is no evidence supporting this practise.
