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Article
Reduction in sella turcica volume
Ten patients with acromegaly were treated with the long-acting somatostatin analogue, Sandostatin (SMS 201-995, octreotide) for more than one year. Computerized tomography was performed before and on 4 differe...
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Chapter and Conference Paper
Effects of Long-Term Administration of Sandostatin® (SMS 201–995) at Increasing Doses in 40 Acromegalic Patients. Results from the French Sandostatin Acromegaly Study Group
Several studies demonstrate the efficacy of short- and long-term Sandostatin® treatment in acromegaly administered subcutaneously at doses ranging from 150 to 300 µg up to 600 µg per day [1, 3, 5, 7–10]. A rhythm...
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Chapter and Conference Paper
Observations During a Clinical Trial of Sandostatin® in Acromegalic Patients
Ten acromegalic patients were studied over a period of 75 weeks. Four had had one or more attempted ablations of their pituitary adenoma, six were previously untreated or had been unsuccessfully treated with b...
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Chapter and Conference Paper
Long-Term Treatment of Acromegaly by Continuous Subcutaneous Infusion of the Long-Acting Somatostatin Analog Sandostatin® (SMS 201–995, Octreotide)
Recently the long-acting somatostatin analog Sandostatin® (SMS 201–995, Octreotide) was introduced for the therapy of acromegaly. On a two or three daily subcutaneous (s.c.) injection regimen plasma GH levels hav...
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Chapter and Conference Paper
Long-Term Efficacy of Sandostatin®(SMS 201–995, Octreotide) in 178 Acromegalic Patients. Results from the International Multicentre Acromegaly Study Group
Sandostatin® (SMS 201–995), a synthetic long-acting octapeptide, represents an efficacious alternative therapeutic candidate to available treatment modalities for acromegaly.