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  1. Article

    Open Access

    Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome

    The CXCL10/CXCR3 signalling mediates paracrine interactions between tumour and stromal cells that govern leukocyte trafficking and angiogenesis. Emerging data implicate noncanonical CXCL10/CXCR3 signalling in ...

    S C Wightman, A Uppal, S P Pitroda, S Ganai, B Burnette in British Journal of Cancer (2015)

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    Article

    Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor

    NF-κB proteins play a central and subunit-specific role in the response to DNA damage. Previous work identified p50/NF-κB1 as being necessary for cytotoxicity in response to DNA alkylation damage. Given the im...

    D J Voce, A M Schmitt, A Uppal, M E McNerney, G M Bernal, K E Cahill in Oncogene (2015)