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Article
Distribution of Vascular Patterns in Different Subtypes of Renal Cell Carcinoma. A Morphometric Study in Two Distinct Types of Blood Vessels
To analyze the presence of mature and immature vessels as a prognostic factor in patients with renal cell carcinoma and propose a classification of renal cancer tumor blood vessels according to morphometric pa...
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Article
Microvessel density is high in clear-cell renal cell carcinomas of Ukrainian patients exposed to chronic persistent low-dose ionizing radiation after the Chernobyl accident
During the 25-year period subsequent to the Chernobyl accident, the morbidity of malignant renal tumors in Ukraine has increased from 4.7 to 10.7 per 100,000 of the total population. Recent studies of our grou...
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Article
1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma
Despite extensive characterization of the role of the EWS-ETS fusions, little is known about secondary genetic alterations and their clinical contribution to Ewing sarcoma (ES). It has been demonstrated that t...
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Chapter
TuBaFrost: European Virtual Tumor Tissue Banking
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Article
Small-cell carcinoma of the urinary bladder. A clinico-pathological study of ten cases
Small-cell carcinoma (SCC) of the urinary bladder is an infrequent neoplasia accounting for 0.5% of all tumors located at this level. There is a predilection for males over females with a 4:1 proportion and a ...
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Article
Radiation sclerosing proliferative atypical nephropathy of peritumoral tissue of renal-cell carcinomas after the Chernobyl accident in Ukraine
After the Chernobyl accident, the morbidity of renal-cell carcinomas in Ukraine increased gradually from 4.7 to 7.5 per 100,000 of the total population. Cesium 137 (137Cs) is responsible for 80–90% of the intern...
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Article
Analysis of p53 and mdm2 proteins in malignant fibrous histiocytoma in absence of gene alteration: prognostic significance
TP53 and MDM2 genes and their protein expression were evaluated in frozen and paraffin-embedded tissue from 27 patients with malignant fibrous histiocytoma to elucidate the relationship between them, their impl...
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Article
Absence of p53 gene mutations in hepatocarcinomas from a Mediterranean area of Spain
The incidence of p53 gene abnormalities in human hepatocellular carcinoma (HCC) varies in different geographical areas, being higher in regions where hepatitis virus infection and dietary exposure to aflatoxin B...
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Article
Endometrial stromal sarcomas: immunohistochemical, electron microscopical and cytogenetic findings in two cases
Uterine sarcomas are approximately 3% of all malignant uterine corpus tumours. Of these, the tumours that originate solely in the stromal elements of the uterine wall are infrequent and have not been well cha...
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Article
FU-3 monoclonal antibody: a specific marker for malignant fibrous histiocytoma? An analysis of 32 malignant soft tissue and bone sarcomas
An immunohistochemical study on frozen sections was carried out on 51 malignant tumours of soft tissue and bone using the FU-3 monoclonal antibody. This antibody is claimed to be specific for malignant fibrous...
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Article
Cytogenetics, flow cytometry, cytophotometry and morphometry of 22 cases of primary breast carcinoma
Cytogenetic, flow cytometric, cytophotometric and morphometric analyses were performed on 22 previously untreated, primary solid breast carcinomas. Although the cell nuclei as the primary object of these studi...
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Chapter
Primitive Neuroectodermal Tumor of the Testis: Report of a New Case with Cytogenetic and Cell Culture Analysis
We present a new case of primitive neuroectodermal tumor (PNET) of the testis diagnosed in a 21—year-old man. Microscopically, the tumor was composed of immature neuroectodermal tissue with ependymal and neuro...
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Article
Giant-cell tumor of bone, stage II, displaying translocation t(12;19)(q13;q13)
A new case of giant-cell tumour (GCT) of bone with benign histological features, clinical stage II, has been reviewed with immunohistochemistry and electron microscopy. After short-term tissue culture the kary...
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Article
Pigmented esthesioneuroblastoma showing dual differentiation following transplantation in nude mice
Esthesioneuroblastoma (ESTH) is a neuroepithelial-cell-derived neoplasm of the olfactory mucosa composed of homogeneous small round cells which contain neurosecretory granules. Melanin has been detected in suc...
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Article
Malignant peripheral neuroectodermal tumours of bone other than Askin's neoplasm: characterization of 14 new cases with immunohistochemistry and electron microscopy
Peripheral neuroectodermal tumours (PNET) of bone are rare and mimick those seen in soft tissue (peripheral neuroepithelioma of soft tissue). Their differential diagnosis from Ewing's sarcoma (Es) is extremely...
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Article
Morphometric and cytophotometric nuclear analysis of altered hepatocyte foci induced by N-nitrosomorpholine (NNM) and aflatoxin B1 (AFB1) in liver of Wistar rats
The progressive morphological changes in the liver during neoplastic transformation have been studied by histological, cytophotometric and morphometric methods in male Wistar rats treated with two carcinogens:...
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Article
Histopathological predictive factors in Ewings's sarcoma of bone and clinicopathological correlations
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Article
S-100 protein positive cells in nasopharyngeal carcinoma (NPC): Absence of prognostic significance
An immunohistochemical study of S-100 protein in 43 nasopharyngeal carcinomas (NPC) of known clinical evolution (33 primary and 10 metastatic) is presented. Sixty per cent of primary site cases as well as all ...
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Article
Histopathological predictive factors in Ewing's sarcoma of bone and clinicopathological correlations
A retrospective multifactorial analysis on 261 previously untreated patients with Ewing's sarcoma (Es) of bone has been carried out in order to ascertain the prognostic value of several histological variables ...
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Chapter and Conference Paper
Zur experimentellen Erzeugung von Ovarialtumoren
Die Bemühungen um die experimentelle Erzeugung von Ovarialtumoren im Versuchstier erbrachten seit Zondek’s Entdeckung (zitiert nach Biskind u. Biskind 1944) des Östrogenabbaus in der Leber (1934) zahlreiche Mo...
