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    Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

    CARCINOGENIC polycyclic hydrocarbons such as the widespread environmental contaminant, benzo(a)pyrene (Fig. 1a), undoubtedly require metabolic activitation. Boyland1 proposed that epoxides, whose formation is cat...

    P. SIMS, P. L. GROVER, A. SWAISLAND, K. PAL, A. HEWER in Nature (1974)