24 Result(s)

Article

Bone marrow fibrosis in childhood acute lymphoblastic leukemia correlates to biological factors, treatment response and outcome

We retrospectively evaluated reticulin fiber density (RFD) in 166 diagnostic bone marrow (BM) biopsies and 62 biopsies obtained at treatment day 29 from children with acute lymphoblastic leukemia (ALL). Patien...

U Norén-Nyström, G Roos, A Bergh, J Botling, G Lönnerholm, A Porwit, M Heyman… in Leukemia (2008)

Article

Association between the presence of bacterial 16S RNA in prostate specimens taken during transurethral resection of prostate and subsequent risk of prostate cancer (Sweden)

To study bacterial 16S RNA in archival prostate samples from 352 patients with benign prostate hyperplasia (BPH) and evaluate whether the presence of bacterial DNA was different in those who later developed pr...

O. Alexeyev, J. Bergh, I. Marklund, C. Thellenberg-Karlsson… in Cancer Causes & Control (2006)

Article

Prognostic impact of vascular density and fibrosis in the bone marrow of children with high-risk acute lymphoblastic leukemia

U Norén-Nyström, G Roos, A Bergh, E Forestier in Leukemia (2005)

Article

A catheter tactile sensor for measuring hardness of soft tissue: measurement in a silicone model and in anin vitro human prostate model

Tissue hardness is related to tissue composition, and this is often changed by disease. It is therefore of interest to measure the hardness in an objective and non-invasive way. A tactile sensor based on a vib...

A. Eklund, A. Bergh, O. A. Lindahl in Medical & Biological Engineering & Computing (1999)

Article

Transient ischemia induces apoptosis in the ventral prostate of the rat

The mechanisms involved in the castration-induced involution of the ventral prostate (VP) are not fully understood. It was recently reported that castration decreases blood flow in the VP in rats and that thi...

E. Lekås, C. Engstrand, A. Bergh, J.-E. Damber in Urological Research (1999)

Article

Short-term cellular effects induced by castration therapy in relation to clinical outcome in prostate cancer

To explore the relationship between short-term effects of castration therapy and clinical response, biopsies obtained before and a week after castration therapy from 15 responding and 13 non-responding patient...

P Stattin, P Westin, J-E Damber, A Bergh in British Journal of Cancer (1998)

Article

Decrement of blood flow precedes the involution of the ventral prostate in the rat after castration

Blood flow to the rat ventral prostate (VP), dorsolateral prostate (DP), and Dunning R3327 prostatic tumors was measured at different times up to 7 days after castration, using the microsphere method. In the V...

E. Lekås, M. Johansson, A. Widmark, A. Bergh, J. -E. Damber in Urological Research (1997)

Article

Expression of transforming growth factor-β receptor type I and type II in rat ventral prostate and Dunning R3327 PAP adenocarcinoma in response to castration and oestrogen treatment

In the normal prostate, transforming growth factor-β1 (TGF-β1) inhibits epithelial cell growth and is associated with apoptosis. The role of TGF-β1 in prostate cancer remains, however, unclear. In this work, t...

P. Wikström, A. Bergh, J. -E. Damber in Urological Research (1997)

Article

Bcl-2 immunoreactivity in prostate tumorigenesis in relation to prostatic intraepithelial neoplasia, grade, hormonal status, metastatic growth and survival

The Bcl-2 protein prolongs cell survival by overriding apoptosis. To explore the role of Bcl-2 in prostate tumorigenesis, immunoreactivity for Bcl-2 was examined in untreated and androgen-deprived tumours and ...

P. Stattin, J. -E. Damber, L. Karlberg, H. Nordgren, A. Bergh in Urological Research (1996)

Article

Castration plus oestrogen treatment induces but castration alone suppresses epithelial cell apoptosis in an androgen-sensitive rat prostatic adenocarcinoma

The positive effect of castration in prostatic cancer patients is considered to be related to the induction of apoptosis in androgen-dependent tumour cells. However, castration apparently does not induce apopt...

P Westin, A Brändström, JE Damber, A Bergh in British Journal of Cancer (1995)

Article

Epidermal growth factor receptor content in rat prostatic adenocarcinoma: effects of endocrine treatment

Epidermal growth factor receptor (EGF-R) was studied in Dunning prostatic cancer models using competitive bindings assays and solution hybridization assay. EGF-R-binding capacity and mRNA were demonstrated in ...

J. -E. Damber, A. Bergh, B. Assarsson, M. Gåfvels in Urological Research (1995)

Article

DNA fragmentation induced by the antimitotic drug estramustine in malignant rat glioma but not in normal brain - suggesting an apoptotic cell death

Estramustine, a combination of 17 beta-oestradiol and nor-nitrogen mustard, has been shown to be metabolised and to induce specific antiproliferative effects in malignant glioma, including arrest of glioma cel...

C Vallbo, T Bergenheim, A Bergh, K Grankvist, R Henriksson in British Journal of Cancer (1995)

Article

Localization and quantity of hyaluronan in urogenital organs of male and female rats

The histochemical distribution of hyaluronan was analysed in various urogenital organs of male and female (non-pregnant and pregnant) rats by use of a hyaluronan-binding protein and avidin biotin/peroxidase st...

C. Laurent, S. Hellström, A. Engström-Laurent, A. F. Wells… in Cell and Tissue Research (1995)

Article

Rat testis oedema measured with the impression technique: effects of hyaluronan, albumin, rat plasma and saline

O. A. Lindahl, A. Bergh, J. -E. Damber… in Medical and Biological Engineering and Com… (1994)

Chapter

Effects of Castration and Estrogen Treatment on Tissue Levels of Prostaglandins in the Dunning R3327 Rat Prostatic Adenocarcinoma

The effect of castration alone or in combination with daily injections of estradiol-17β on tissue levels of prostaglandins (PGs) was evaluated in the Dunning R3327 rat prostatic adenocarcinoma model. Within 3 ...

J. Olofsson, A. Bergh, J-E. Damber in Eicosanoids and Other Bioactive Lipids in … (1993)

Article

Studies on the distribution of calcitonin gene-related peptide-like and substance P-like immunoreactivities in rat hind limb muscles

The tibialis anterior, extensor digitorum longus and soleus muscles in the rat were examined with respect to the presence of calcitonin gene-related peptide-like as well as substance P-like immunoreactivity. I...

S. Forsgren, A. Bergh, E. Carlsson, L. E. Thornell in The Histochemical Journal (1992)

Article

Interleukin-2-induced growth inhibition of prostatic adenocarcinoma (Dunning R 3327) in rats

The present study was designed to evaluate the effect of a biological response modifier, interleukin-2 (IL-2), on the growth in rats of Dunning (R3327, androgen sensitive) prostatic adenocarcinoma. IL-2 was gi...

R. Henriksson, A. Widmark, A. Bergh, J. E. Damber in Urological Research (1992)