22 Result(s)
within
**yi Yao
Dentistry
Oral and Maxillofacial Surgery
Surgical Orthopedics
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Article
Open AccessPRX1-positive mesenchymal stem cells drive molar morphogenesis
Mammalian teeth, develo** inseparable from epithelial-mesenchymal interaction, come in many shapes and the key factors governing tooth morphology deserve to be answered. By merging single-cell RNA sequencing...
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Open AccessExpert consensus on odontogenic maxillary sinusitis multi-disciplinary treatment
Odontogenic maxillary sinusitis (OMS) is a subtype of maxillary sinusitis (MS). It is actually inflammation of the maxillary sinus that secondary to adjacent infectious maxillary dental lesion. Due to the lack...
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Open AccessMinimally invasive techniques for lateral maxillary sinus floor elevation: small lateral window and one-stage surgery—a 2–5-year retrospective study
This study aimed to introduce a minimally invasive technique for maxillary sinus floor elevation using the lateral approach (lSFE) and to determine the factors that influence the stability of the grafted area ...
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Open AccessPrimary cilia support cartilage regeneration after injury
In growing children, growth plate cartilage has limited self-repair ability upon fracture injury always leading to limb growth arrest. Interestingly, one type of fracture injuries within the growth plate achie...
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A biomimetic nanoplatform for customized photothermal therapy of HNSCC evaluated on patient-derived xenograft models
Cancer cell membrane (CCM) derived nanotechnology functionalizes nanoparticles (NPs) to recognize homologous cells, exhibiting translational potential in accurate tumor therapy. However, these nanoplatforms ar...
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Open AccessTooth number abnormality: from bench to bedside
Tooth number abnormality is one of the most common dental developmental diseases, which includes both tooth agenesis and supernumerary teeth. Tooth development is regulated by numerous developmental signals, s...
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Open AccessIFT140+/K14+ cells function as stem/progenitor cells in salivary glands
Stem/progenitor cells are important for salivary gland development, homeostasis maintenance, and regeneration following injury. Keratin-14+ (K14+) cells have been recognized as bona fide salivary gland stem/proge...
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Open AccessChromatin conformation of human oral epithelium can identify orofacial cleft missing functional variants
Genome-wide association studies (GWASs) are the most widely used method to identify genetic risk loci associated with orofacial clefts (OFC). However, despite the increasing size of cohort, GWASs are still ins...
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Open AccessKindlin-2 loss in condylar chondrocytes causes spontaneous osteoarthritic lesions in the temporomandibular joint in mice
The progressive destruction of condylar cartilage is a hallmark of the temporomandibular joint (TMJ) osteoarthritis (OA); however, its mechanism is incompletely understood. Here, we show that Kindlin-2, a key ...
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Open AccessTracing PRX1+ cells during molar formation and periodontal ligament reconstruction
Neural crest-derived mesenchymal stem cells (MSCs) are known to play an essential function during tooth and skeletal development. PRX1+ cells constitute an important MSC subtype that is implicated in osteogenesis...
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Open AccessSingle-cell characterization of monolayer cultured human dental pulp stem cells with enhanced differentiation capacity
Human dental pulp stem cells (hDPSCs) are easily obtained multipotent cells, however, their potential value in regenerative medicine is hindered by the phenotypic and functional changes after conventional mono...
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Open AccessLncRNA Nron regulates osteoclastogenesis during orthodontic bone resorption
Activation of osteoclasts during orthodontic tooth treatment is a prerequisite for alveolar bone resorption and tooth movement. However, the key regulatory molecules involved in osteoclastogenesis during this ...
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Open AccessSalivary mycobiome dysbiosis and its potential impact on bacteriome shifts and host immunity in oral lichen planus
The biodiversity of the mycobiome, an important component of the oral microbial community, and the roles of fungal–bacterial and fungal–immune system interactions in the pathogenesis of oral lichen planus (OLP...
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Open AccessERG3 and ERG11 genes are critical for the pathogenesis of Candida albicans during the oral mucosal infection
The hyphal development of Candida albicans (C. albicans) has been considered as an essential virulent factor for host cell damage. However, the missing link between hyphae and virulence of C. albicans is also bee...
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Open AccessAlanine racemase is essential for the growth and interspecies competitiveness of Streptococcus mutans
D-alanine (D-Ala) is an essential amino acid that has a key role in bacterial cell wall synthesis. Alanine racemase (Alr) is a unique enzyme that interconverts L-alanine and D-alanine in most bacteria, making ...
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Open AccessSaliva in the diagnosis of diseases
Saliva is secreted from the salivary glands and has multiple functions, including mouth cleaning and protection, antibacterial effects and digestion. With the rapid advancement in salivaomics, saliva is well r...
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Open AccessExpression analysis of α-smooth muscle actin and tenascin-C in the periodontal ligament under orthodontic loading or in vitro culture
α-smooth muscle actin (α-SMA) and tenascin-C are stress-induced phenotypic features of myofibroblasts. The expression levels of these two proteins closely correlate with the extracellular mechanical microenvir...
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Open AccessEffects of 45S5 bioglass on surface properties of dental enamel subjected to 35% hydrogen peroxide
Tooth bleaching agents may weaken the tooth structure. Therefore, it is important to minimize any risks of tooth hard tissue damage caused by bleaching agents. The aim of this study was to evaluate the effects...
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Open AccessUrinary levels of nickel and chromium associated with dental restoration by nickel–chromium based alloys
This paper aims to investigate if the dental restoration of nickel–chromium based alloy (Ni–Cr) leads to the enhanced excretions of Ni and Cr in urine. Seven hundred and ninety-five patients in a dental hospit...
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Open AccessChemical composition of Galla chinensis extract and the effect of its main component(s) on the prevention of enamel demineralization in vitro
To determine the chemical composition of Galla chinensis extract (GCE) by several analysis techniques and to compare the efficacy of GCE and its main component(s) in inhibition of enamel demineralization, for the...
