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  1. Article

    Open Access

    Bibliometric and visual analysis in the field of two-dimensions nano black phosphorus in cancer from 2015 to 2023

    This study aims to provide a comprehensive summary of the status and trends of Two-Dimensional Nano Black Phosphorus (2D nano BP) in cancer research from 2015 to 2023, offering insights for future studies. To ...

    **g’an Huang, Ling Zhang, Boren Li, Yuanchu Lian, **aoxin Lin in Discover Oncology (2024)

  2. No Access

    Article

    Tracking-seq reveals the heterogeneity of off-target effects in CRISPR–Cas9-mediated genome editing

    The continued development of novel genome editors calls for a universal method to analyze their off-target effects. Here we describe a versatile method, called Tracking-seq, for in situ identification of off-t...

    Ming Zhu, Runda Xu, Junsong Yuan, Jiacheng Wang, **aoyu Ren in Nature Biotechnology (2024)

  3. Article

    Open Access

    Prognostic significance of hemoglobin, albumin, lymphocyte, and platelet (HALP) score in breast cancer: a propensity score-matching study

    The hemoglobin-albumin-lymphocyte-platelet (HALP) score functions as a comprehensive index that assesses the systemic inflammatory response, nutritional, and immune status. This study aimed to explore the rela...

    Tongchao Jiang, Haishuang Sun, Shuyu Xue, Tiankai Xu, Wen **a in Cancer Cell International (2024)

  4. No Access

    Article

    E-DBRL: efficient double broad reinforcement learning for adaptive traffic signal control

    Efficient traffic signal management is crucial for regulating traffic flow and fostering sustainable development within road transportation systems. To address the challenges in traffic management, numerous st...

    **aoheng Deng, Shunmeng Yin, **njun Pei, Lixin Lin, Xuechen Chen in Applied Intelligence (2024)

  5. Article

    Open Access

    Effects of Staphylococcus aureus on stem cells and potential targeted treatment of inflammatory disorders

    Due to the advanced studies on stem cells in developmental biology, the roles of stem cells in the body and their phenotypes in related diseases have not been covered clearly. Meanwhile, with the intensive res...

    Zi-xian Liu, Guan-qiao Liu, Ze-xin Lin, Ying-qi Chen in Stem Cell Research & Therapy (2024)

  6. Article

    Open Access

    Analysis of tumor microenvironment alterations in partially responsive rectal cancer patients treated with neoadjuvant chemoradiotherapy

    Achieving a pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (NCRT) remains a challenge for most patients with rectal cancer. Exploring the potential of combining NCRT with immunotherapy ...

    Hong Chen, Ji-Hong Zhang, Qin Hao in International Journal of Colorectal Disease (2024)

  7. Article

    Open Access

    U-shaped association between triglyceride-glucose index and all-cause mortality among critically ill pediatrics: a population-based retrospective cohort study

    Previous studies have shown that an elevated triglyceride-glucose (TyG) index was associated with all-cause mortality in both general adult individuals and critically ill adult patients. However, the relations...

    Qi Gao, Fan Luo, Hongxue Yu, Yuxin Lin, Ruqi Xu, **** Li in Cardiovascular Diabetology (2024)

  8. Article

    Open Access

    Emerging roles of ferroptosis in pulmonary fibrosis: current perspectives, opportunities and challenges

    Pulmonary fibrosis (PF) is a chronic interstitial lung disorder characterized by abnormal myofibroblast activation, accumulation of extracellular matrix (ECM), and thickening of fibrotic alveolar walls, result...

    Yixiang Hu, Ying Huang, Lijuan Zong, Jiaxin Lin, **ang Liu in Cell Death Discovery (2024)

  9. No Access

    Article

    Hydrogen Sulfide can Scavenge Free Radicals to Improve Spinal Cord Injury by Inhibiting the p38MAPK/mTOR/NF-κB Signaling Pathway

    Spinal cord injury (SCI) causes irreversible cell loss and neurological dysfunctions. Presently, there is no an effective clinical treatment for SCI. It can be the only intervention measure by relieving the sy...

    Kexin Lin, Yong Zhang, Yanyang Shen, Yiqin Xu, Min Huang in NeuroMolecular Medicine (2024)

  10. Article

    Open Access

    Hippocampal and orbitofrontal neurons contribute to complementary aspects of associative structure

    The ability to establish associations between environmental stimuli is fundamental for higher-order brain functions like state inference and generalization. Both the hippocampus and orbitofrontal cortex (OFC) ...

    Huixin Lin, **gfeng Zhou in Nature Communications (2024)

  11. Article

    Open Access

    Tumor initiation and early tumorigenesis: molecular mechanisms and interventional targets

    Tumorigenesis is a multistep process, with oncogenic mutations in a normal cell conferring clonal advantage as the initial event. However, despite pervasive somatic mutations and clonal expansion in normal tis...

    Shaosen Zhang, **nyi **ao, Yonglin Yi in Signal Transduction and Targeted Therapy (2024)

  12. No Access

    Article

    Brief mindfulness intervention attenuates self-serving bias rather than boosts self-enhancement

    The relationship between mindfulness and self-enhancement has been a topic of debate in recent years. While some researchers have found that mindfulness practitioners exhibit higher levels of self-enhancement ...

    Yingqi Gu, **n Lin, Weiwu Yu, Yating Liu in Current Psychology (2024)

  13. Article

    Open Access

    Influence of protective clothing and masks on facial trustworthiness in an investment game: insights from a Chinese population study

    Facial features are important sources of information about perceived trustworthiness. Masks and protective clothing diminish the visibility of facial cues by either partially concealing the mouth and nose or c...

    Wei** Wang, Zhifan Li, **n Lin in Cognitive Research: Principles and Implica… (2024)

  14. Article

    Open Access

    Aberrant expression of B7-H4 and B7-H5 contributes to the development of cutaneous squamous cell carcinoma

    Cutaneous squamous cell carcinoma (CSCC) is the second most common malignant tumor of the skin. B7 homolog 4 (B7-H4) and B7-H5 (B7 homolog 5) are associated with a variety of tumors. Investigate the potential ...

    Lu Chen, Bin Zhou, Minhui Tang, Yuxu Yao, Yue Zhao in Archives of Dermatological Research (2024)

  15. No Access

    Article

    Pathogenesis-Related Protein 10 Family Genes Involved in Sugarcane Responses to Biotic Stressors and Salicylic Acid

    Pathogenesis-related protein 10 (PR10) family genes play a crucial role in plant defense against various stressors. However, gene member and function identification of PR10 family in sugarcane remain largely u...

    Liang-Nian Xu, **a-Ran Jiang, Jia-**n Lin, Juan Li in Journal of Plant Growth Regulation (2024)

  16. No Access

    Article

    ASO Visual Abstract: Long-Term Outcomes of Orthotopic Neobladder versus Ileal Conduit Urinary Diversion in Robot-Assisted Radical Cystectomy (RARC): Multicenter Results from the Asian RARC Consortium

    Chris Ho-ming Wong MBChB, Ivan Ching-ho Ko MBChB in Annals of Surgical Oncology (2024)

  17. No Access

    Article

    Advancements of Macrophages Involvement in Pathological Progression of Colitis-Associated Colorectal Cancer and Associated Pharmacological Interventions

    Intestinal macrophages play crucial roles in both intestinal inflammation and immune homeostasis. They can adopt two distinct phenotypes, primarily determined by environmental cues. These phenotypes encompass ...

    Jun-yu Ke, **-bin Song, Long Li, Zhen-fan He in Chinese Journal of Integrative Medicine (2024)

  18. No Access

    Article

    Reply to Qiao et al.

    Zibin Chen, Kaixin Lin, Huichuan Yu in British Journal of Cancer (2024)

  19. No Access

    Article

    DMF-scMT-seq linking methylome and transcriptome within single cells with digital microfluidics

    Single-cell joint analysis of methylome and transcriptome reveals how the methylation regulates the transcriptional activity. However, traditional bench-top protocols for single-cell DNA methylation and RNA tr...

    **ng Xu, ** Zeng, **n Lin, Shiyan Lin, Shanshan Liang, Tian Tian in Science China Chemistry (2024)

  20. No Access

    Article

    Cell-specific localization of β-synuclein in the mouse retina

    β-synuclein, a member of the synuclein family, is frequently co-expressed with α-synuclein in the neural system, where it serves to inhibit abnormal aggregation of α-synuclein in neurodegenerative diseases. Be...

    Wenhui Zhong, Qingwen Yang, Fenglan Wang, **n Lin in Brain Structure and Function (2024)

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