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Article
A non-invasive glucose sensor based on 3D reduced graphene oxide-MXene and AuNPs composite electrode for the detection of saliva glucose
Regular monitoring of blood glucose levels is crucial in diabetes management. Commonly used procedures may be invasive and can lead to cross-infection and inflammation. Therefore, a safe, non-invasive blood gl...
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Article
Experimental study on shear weakening mechanism of local roughness for rough rock fracture surface in different directions
The morphological characteristics of the fracture surface play a crucial role in determining its shear strength and deformation. Additionally, the fracture surface undergoes varying degrees of damage at differ...
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Article
Autophagy Regulation Attenuates Neuroinflammation and Cognitive Decline in an Alzheimer's Disease Mouse Model with Chronic Cerebral Hypoperfusion
This study investigates the role of autophagy regulation in modulating neuroinflammation and cognitive function in an Alzheimer's disease (AD) mouse model with chronic cerebral hypoperfusion (CCH). Using the A...
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Article
Open AccessInflammation accelerating intestinal fibrosis: from mechanism to clinic
Intestinal fibrosis is a prevalent complication of IBD that that can frequently be triggered by prolonged inflammation. Fibrosis in the gut can cause a number of issues, which continue as an ongoing challenge ...
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Article
Open AccessInvestigating the impact of a large river and its surrounding contextual conditions on pedestrians’ summer thermal perceptions in a Cfa-climate city
Thermal comfort studies are usually employed to find subjective thermal responses [indicated by neutral temperature (NT), i.e. the temperature with no thermal stress] of residents from a region towards thermal...
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Article
Effects of Testosterone in Mediating the Relationship Between Daytime Nap** and Osteoporosis in European Populations: A Mendelian Randomization Study
We aimed to explore the causal effect of daytime nap** on the risk of osteoporosis and the mediation role of testosterone in explaining this relationship. Summary data for Mendelian randomization (MR) analys...
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Article
PPP2CA Inhibition Promotes Ferroptosis Sensitivity Through AMPK/SCD1 Pathway in Colorectal Cancer
Colorectal cancer (CRC) is a very common malignancy of the digestive system. Despite a variety of treatments including surgery, chemotherapeutic and targeted drugs, the prognosis for patients with CRC is still...
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Article
Open AccessA non-image-forming visual circuit mediates the innate fear of heights in male mice
The neural basis of fear of heights remains largely unknown. In this study, we investigated the fear response to heights in male mice and observed characteristic aversive behaviors resembling human height vert...
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Article
Retraction Note: Silencing POLE2 promotes apoptosis and inhibits proliferation of oral squamous cell carcinomas by inhibiting PI3K/AKT signaling pathway
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Article
Open AccessUnveiling the link between lactate metabolism and rheumatoid arthritis through integration of bioinformatics and machine learning
Rheumatoid arthritis (RA) is a persistent autoimmune condition characterized by synovitis and joint damage. Recent findings suggest a potential link to abnormal lactate metabolism. This study aims to identify ...
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Article
The toxic impacts of microplastics-borne benzo[a]pyrene and heavy metals on the health and behavior of seahorse Hippocampus erectus
Marine pollution poses a critical threat to biodiversity. The synergistic effects of microplastics, specifically high-density polyethylene (HDPE), combined with benzo[a]pyrene (B[a]P) and heavy metals, on the ...
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Article
Correction to: Melatonin enhances the tolerance of apple seedlings to salt stress by regulating the microbial community structure and metabolite composition of the rhizosphere
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Article
Influence of multi-element bonding phase composition on the preparation and properties of pressureless-sintered (Ta, Nb, Ti, V, W)C high-entropy ceramics
Four kinds of (Ta, Nb, Ti, V, W)C high-entropy ceramics with different combinations of bonding phases, namely Co, CoNi, CoNiCr, and CoNiCrFe, have been successfully prepared by conventional pressureless sinter...
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Article
Melatonin enhances the tolerance of apple seedlings to salt stress by regulating the microbial community structure and metabolite composition of the rhizosphere
The potential roles of melatonin (MT) in alleviating salt stress in apple plants (Malus hupehensis) are not understood.
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Article
Microstructures and Properties of WC-10 wt.%CoCrFeNiAlx Composite Cemented Carbides
In this paper, WC-10 wt.%CoCrFeNiAlx cemented carbide was prepared by a vacuum pressureless tube furnace using the high-entropy alloy CoCrFeNiAlx (x = 0, 0.25, 0.5, 0.75, 1.0) as the binder phase. The effects of ...
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Article
Clinical effect of roxadustat vs. erythropoietin in non-dialysis CKD with diabetes: a single center propensity score matching analysis
Renal anemia is a common complication of chronic kidney disease. Currently, recombinant human erythropoietin and roxadustat are the main treatments. In China, diabetic kidney disease is the primary cause of ch...
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Article
Effect of Different Pretreatment Methods on Drying Characteristics and Quality of Wolfberry (Lycium barbarum) by Radio Frequency-Hot Air Combined Segmented Drying
In this study, fresh wolfberry in the current season was used as the experimental material, and a radio frequency (RF)-hot air combined segmented drying process was adopted for berry preservation. Ultrasonic t...
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Article
Automated synthesis of oxygen-producing catalysts from Martian meteorites by a robotic AI chemist
Living on Mars requires the ability to synthesize chemicals that are essential for survival, such as oxygen, from local Martian resources. However, this is a challenging task. Here we demonstrate a robotic art...
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Article
Open AccessIdentifying functional subtypes of IgA nephropathy based on three machine learning algorithms and WGCNA
IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis, which is a significant cause of renal failure. At present, the classification of IgAN is often limited to pathology, and its molecul...
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Article
Discriminative latent subspace learning with adaptive metric learning
Least squares regression (LSR) has been widely used in the field of pattern recognition. However, LSR-based classifier still suffers from the following issues. One is that it focuses only on the dependency bet...
