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Article
Autophagy Regulation Attenuates Neuroinflammation and Cognitive Decline in an Alzheimer's Disease Mouse Model with Chronic Cerebral Hypoperfusion
This study investigates the role of autophagy regulation in modulating neuroinflammation and cognitive function in an Alzheimer's disease (AD) mouse model with chronic cerebral hypoperfusion (CCH). Using the A...
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Article
Open AccessThe clinical effectiveness of sivelestat in treating sepsis patients with both acute respiratory distress syndrome and septic cardiomyopathy
We aimed to assess the efficacy of the neutrophil elastase inhibitor, sivelestat, in the treatment of sepsis-induced acute respiratory distress syndrome (ARDS) and septic cardiomyopathy (SCM).
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Article
In Situ Synthesis of Monolithic TS‑1 on Nitrogen-Doped Carbon Layer Decorated Nickel Foam with Small Particle TS-1 and High Content of Lewis Acid
Monolithic TS-1 can solve the problem of industrial separation caused by TS-1 powder, However, the influence of the support on the internal structure of TS-1 remains to be studied. The support capable of regul...
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Article
Delayed postoperative neurological deficits from scoliosis correction: a case series and systematic review on clinical characteristics, treatment, prognosis, and recovery
This study was designed to investigate the clinical features, treatment modalities, and risk factors influencing neurological recovery in patients who underwent scoliosis correction with delayed postoperative ...
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Article
Open AccessCircular RNA MKLN1 promotes epithelial-mesenchymal transition in pulmonary fibrosis by regulating the miR-26a/b-5p/CDK8 axis in human alveolar epithelial cells and mice models
Pulmonary fibrosis involves destruction of the lung parenchyma and extracellular matrix deposition. Effective treatments for pulmonary fibrosis are lacking and its pathogenesis is still unclear. Studies have f...
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Article
Untargeted metabolomics identifies indole-3-propionic acid to relieve Ang II-induced endothelial dysfunction in aortic dissection
Indole-3-propionic acid (IPA), a gut microbiota-derived metabolite of tryptophan, has been proven to fulfill an essential function in cardiovascular disease (CVD) and nerve regeneration disease. However, the r...
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Article
Image deblocking algorithm based on GC and SSR
Block discrete cosine transform coding has been widely used in image and video compression standards. However, at low bit rate coding, the compressed image produces obvious block effects at the block boundarie...
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Article
Genetic lineage tracing identifies adaptive mechanisms of pancreatic islet β cells in various mouse models of diabetes with distinct age of initiation
During the pathogenesis of type 1 diabetes (T1D) and type 2 diabetes (T2D), pancreatic islets, especially the β cells, face significant challenges. These insulin-producing cells adopt a regeneration strategy t...
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Article
Open AccessFactors affecting medical students’ intention to use Rain Classroom: a cross-sectional survey
Rain Classroom was one of the most popular online learning platforms in Chinese higher education during the pandemic. However, there is little research on user intention under the guidance of technology accept...
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Article
Defect detection in automotive glass based on modified YOLOv5 with multi-scale feature fusion and dual lightweight strategy
Automotive glass is one of the key components in manufacturing engineering, and the inspection of defects is essentially an important item of quality evaluation. Deep learning has become a promising technology...
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Chapter and Conference Paper
Formation Tracking for Autonomous Surface Vessels Based on an Improved Reaching Law
This paper focuses on the formation tracking problem for autonomous surface vessels. In current works, there are challenges regarding the convergence time and chattering in autonomous surface vessels formation...
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Chapter and Conference Paper
A New Comparison Function Based Direct Multisearch Method for Derivative-Free Multi-objective Optimization Problems
In this paper, for addressing Multi-Objective Derivative-Free Optimization (MODFO) problems with box constraints, a new direct multisearch algorithm named CmpFDMS is proposed. The method dose not aggregate obj...
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Chapter and Conference Paper
AGST-LSTM: The ConvLSTM Model Combines Attention and Gate Structure for Spatiotemporal Sequence Prediction Learning
Spatiotemporal sequence prediction learning generates one or more frames of images by learning from multiple frames of historical input. Most current spatiotemporal sequence prediction learning methods do not ...
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Chapter and Conference Paper
Signed Average Consensus of Signed Networks Under Directed Communication Topologies
In this document, signed average consensus problems are investigated for signed networks under directed communication topologies based on sampled information. To achieve this goal, a distributed control protoc...
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Article
A comparative study on hemostasis effect of different application methods and time of tranexamic acid in total hip arthroplasty
To analyze the hemostatic effect of different application methods and time of tranexamic acid (TXA) on primary unilateral total hip arthroplasty.
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Article
Episodic symptoms caused by neurovascular conflict of vagus nerve due to hemilateral anterior inferior cerebellar artery
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Article
Open AccessPreparation and adsorption properties of magnetic chitosan/sludge biochar composites for removal of Cu2+ ions
The magnetic chitosan/sludge biochar composite adsorbent was prepared using chitosan, Fe3O4, and sludge biochar as raw materials. The composite adsorbent was able to achieve rapid solid–liquid separation under an...
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Article
A case of endobronchial metastasis of colon cancer mimics sarcoidosis, and a review of related literature
Endobronchial metastases (EBM) are defined as bronchoscopically visible lesions histopathologically identical to extrapulmonary tumors. We summarized the literature on endobronchial metastasis of colorectal ca...
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Article
Divergent synthesis of chiral amines via Ni-catalyzed chemo- and enantioselective hydrogenation of alkynone imines
Ligand-mediated nickel-catalyzed asymmetric hydrogenation of alkynone imines has been achieved. By using Ni(OAc)2·4H2O/(S, S)-Ph-BPE complex as a catalyst, the chemo- and enantioselective hydrogenation of alkynon...
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Article
DNA-based programmable gate arrays for general-purpose DNA computing
The past decades have witnessed the evolution of electronic and photonic integrated circuits, from application specific to programmable1,2. Although liquid-phase DNA circuitry holds the potential for massive para...