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  1. No Access

    Chapter and Conference Paper

    Cerebroprotective Effects of a Parenteral Flunarizine Formulation

    Since the synthesis of flunarizine over 25 years ago, there have been over 230 experimental and 150 clinical peer-reviewed descriptions of its pharmacological activity. According to the proposed WHO classifica...

    H. L. Edmonds Jr., G. Raque, P. Y. Zhang, S. A. Jenkins… in Cerebral Ischemia and Calcium (1989)

  2. No Access

    Chapter and Conference Paper

    Calcium Movements in Brain During Failure of Energy Metabolism

    The interstitial ion concentrations in brain are maintained within narrow limits. Changes in plasma concentrations are effectively dealt with by the low ionic permeability of the blood-brain barrier combined w...

    E. Zhang, M. Lauritzen, T. Wieloch, A. J. Hansen in Cerebral Ischemia and Calcium (1989)

  3. No Access

    Chapter

    Experimental and clinical use of omental transposition for spinal cord pathology

    In order to evaluate the ability of the omentum to revascularize the spinal cord in an experimental model, a series of experiments were undertaken. This model which we believe is original, involved local ischa...

    Zhan Min-Shu, Jia Hua-Cheng, Wei Rong-Giu, Jiang Qing-Tao, You Yu-Cai… in The Omentum (1990)

  4. No Access

    Chapter and Conference Paper

    Fetal Tissue Grafts for Cerebellar Atrophy in Humans: A Preliminary Report

    Studies of neural grafting by a number of investigators1–8 have demonstrated survival of fetal neurons in host brains Lund et al.9 have demonstrated point-to-point synapse integration of neural grafts.

    Cheng-Yuan Wu, **u-Feng Bao, Cheng Zhang, Qing-Lin Zhang in Surgery of the Spinal Cord (1992)

  5. No Access

    Article

    Proliferative assessment of craniopharyngioma and epidermoid by nucleolar organizer region staining

    The histologic distinction between craniopharyngioma and epidermoid is equivocal. Eight craniopharyngiomas and ten epidermoids (including three dermoids) as well as nine rat (Wistar) abdominal skins that acted...

    Shuji Niikawa, Akira Hara, Wei Zhang, Noboru Sakai, Hiromu Yamada… in Child's Nervous System (1992)

  6. No Access

    Article

    Histochemistry with Helix pomatia agglutinin in human germ cell tumors: detection of nongerminomatous components and correlation between HPA reactivity and radiosensitivity in germinomas

    Binding sites of Helix pomatia agglutinin (HPA) were examined in 32 patients with intracranial human germ cell tumors. HPA reactivity was found in vascular endothelial cells and erythrocytes of patients with bloo...

    Shuji Niikawa, Noboru Sakai, Hiromu Yamada, Wei Zhang, Akira Hara… in Child's Nervous System (1993)

  7. No Access

    Article

    Angiographic differentiation of carotid cave aneurysms from ventral paraclinoid carotid aneurysms of Nutik type

    Although it appears that carotid cave and ventral paraclinoid carotid aneurysms are different types of internal carotid artery (ICA) aneurysms, it can be difficult to differentiate the two on the basis of angi...

    Qing-Jun Zhang, Shigeaki Kobayashi, Toshihide Toriyama… in Neurosurgical Review (1993)

  8. No Access

    Chapter and Conference Paper

    Microvascular Decompression by the Retromastoid Approach for Idiopathic Hemifacial Spasm: Experience of 300 Patients

    Our experience is reported of 300 patients with idiopathic hemifacial spasm in which microvascular decompression was accomplished by the retromastoid approach between April 1985 and January 1992. The surgical ...

    K. W. Zhang, Z. T. Shun in The Facial Nerve (1994)

  9. No Access

    Chapter and Conference Paper

    The Molecular Biology of Hormone and Growth Factor Receptors in Meningiomas

    Expression of a number of steroid hormone and growth factor receptors is characteristic of meningiomas. This paper reviews the analysis of receptors for progesterone, estrogen, androgen and platelet derived gr...

    Dr. Peter Black, R. Carroll, J. Zhang in Modern Neurosurgery of Meningiomas and Pit… (1996)

  10. No Access

    Article

    Hormone receptors in vestibular schwannomas

    The possibility that steroid hormones play a role in vestibular schwannoma proliferation has been suggested by a number of investigators. There is conflicting information about the presence of steroid hormone ...

    R. S. Carroll, J. P. Zhang, P. Mc L. Black in Acta Neurochirurgica (1997)

  11. No Access

    Article

    The effect of sodium thiosulfate on ototoxicity and pharmacokinetics after cisplatin treatment in guinea pigs

    The effect of sodium thiosulfate (STS) on the pharmacokinetics and ototoxicity of cisplatin (CDDP) was investigated in guinea pigs. Animals received three intramuscular injections of 7.5 mg/kg CDDP separated b...

    T. Saito, Z. J. Zhang, Y. Manabe, T. Ohtsubo… in European Archives of Oto-Rhino-Laryngology (1997)

  12. No Access

    Article

    Osteosarcoma of the meninges in association with glioblastoma

    Primary intracranial osteosarcoma not originating in the skull is a distinctly rare tumour, as is post-irradiation sarcoma of short latency. The authors report the case of a 56 year old caucasian male who unde...

    W. T. Couldwell M.D., Ph.D., B. W. Scheithauer, S. G. Rice… in Acta Neurochirurgica (1997)

  13. No Access

    Article

    Apoptosis in astrocytic neoplasms

    Apoptosis is a form of programmed cell death characterized by specific morphologic and biochemical properties. Tumorgenesis is the consequence not only of cell proliferation but also the loss of the ability to...

    R. S. Carroll, J. Zhang, B. W. Chauncey, K. Chantziara… in Acta Neurochirurgica (1997)

  14. No Access

    Chapter and Conference Paper

    The Clot Thickens — Thrombolysis and Combination Therapies

    Stroke in the human is most frequently caused by an intra-arterial clot. In order to investigate human stroke, appropriate and relevant animal models must be selected. Since the only approved treatment of stro...

    Michael Chopp Ph.D., R. L. Zhang… in Current Progress in the Understanding of S… (1999)

  15. No Access

    Chapter and Conference Paper

    Delayed Gene Expression and Ischemic Brain Injury

    There is increasing evidence that cerebral ischemic injury occurs at a slower pace than previously believed. Although in areas of severe ischemia tissue damage occurs relatively rapidly, in regions of less-sev...

    C. Iadecola, M. E. Ross, F. Zhang, S. Nogawa… in Maturation Phenomenon in Cerebral Ischemia… (1999)

  16. No Access

    Chapter and Conference Paper

    Protein Expression and Brain Plasticity After Transient Middle Cerebral Artery Occlusion in the Rat

    After a stroke, both animals and humans can regain lost function. The molecular basis of this functional plasticity is unknown. In this manuscript, we describe developmental protein expression in the ischemic ...

    M. Chopp, Y. Li, Z. G. Zhang in Maturation Phenomenon in Cerebral Ischemia III (1999)

  17. No Access

    Chapter and Conference Paper

    Morphological Presentation of Posttraumatic Vasospasm

    Posttraumatic vasospasm is a well-recognized sequela of head injury. The risk factors associated with posttraumatic vasospasm have not been well defined. We studied 119 consecutive patients with head injury to...

    Alexander Y. Zubkov M.D., A. S. Pilkington, A. D. Parent, J. Zhang in Brain Edema XI (2000)

  18. No Access

    Chapter and Conference Paper

    Mitogen-Activated Protein Kinase Plays an Important Role in Hemolysate-Induced Contraction in Rabbit Basilar Artery

    Object. Mitogen-activated protein kinase (MAPK) is an important signaling factor in the vascular proliferation and contraction, the two features of cerebral vasospasm following subarachnoid hemor...

    A. Y. Zubkov, K. Ogihara, A. Patllola, A. D. Parent… in Brain Edema XI (2000)

  19. No Access

    Chapter and Conference Paper

    Role of Tyrosine Kinase in Fibroblast Compaction and Cerebral Vasospasm

    Hemolysate, a proposed causative agent for cerebral vasospasm following subarachnoid hemorrhage, produces contraction of cerebral arteries by activation of tyrosine kinases. In addition, hemolysate accelerates...

    A. Patlolla, K. Ogihara, A. Zubkov, K. Aoki, A. D. Parent… in Brain Edema XI (2000)

  20. No Access

    Chapter and Conference Paper

    Oxyhemoglobin Produces Necrosis in Cultured Smooth Muscle Cells

    Object. Myonecrosis in the tunica media, which is defined morphologically, is one of the most striking alterations in the cerebral arterial wall following subarachnoid hemorrhage (SAH). In this s...

    K. Ogihara, A. Y. Zubkov, A. D. Parent, John H. Zhang M.D., Ph.D. in Brain Edema XI (2000)

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