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Article
Open AccessMetabolomics reveals ascorbic acid inhibits ferroptosis in hepatocytes and boosts the effectiveness of anti-PD1 immunotherapy in hepatocellular carcinoma
Immunotherapy combined with molecular targeted therapy is increasingly popular in patients with advanced hepatocellular carcinoma (HCC). However, immune-related adverse events(irAEs) brought on by immunotherap...
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Article
Global zombie companies: measurements, determinants, and outcomes
Academics and practitioners are increasingly concerned about global zombieism, a term used to describe insolvent firms that survive with the support of financial institutions, investors, or governments, partic...
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Article
Open AccessRipa-56 protects retinal ganglion cells in glutamate-induced retinal excitotoxic model of glaucoma
Glaucoma is a prevalent cause of blindness globally, characterized by the progressive degeneration of retinal ganglion cells (RGCs). Among various factors, glutamate excitotoxicity stands out as a significant ...
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Article
Open AccessCausal associations of COVID‐19 on neurosurgical diseases risk: a Mendelian randomization study
Many researchers have explored the potential association between one neurosurgical disease and coronavirus disease 2019 (COVID-19), but few systematically analyzed the association and causality between COVID-1...
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Article
WMBAL: weighted minimum bounds for active learning
In the present study, aimed at reliably acquiring difficult samples for object detection models from massive raw data, we propose a novel difficult sample mining strategy based on active learning with Weighted...
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Article
The impact of climate change and human activities on the change in the net primary productivity of vegetation—taking Sichuan Province as an example
Vegetation is an essential component of terrestrial ecosystems, influenced by climate change and human activities. Quantifying the relative contributions of climate change and human activities to vegetation dy...
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Chapter and Conference Paper
Engine Mount Stopper Abnormal Noise Analytical Method and Solution
According to solve three different types of engine mount stopper noise or abnormal vibration problem, including assembly issue, Y direction stopper issue and X direction stopper issue, detailed description the...
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Chapter and Conference Paper
Diagnosis Method for Eccentric Fault Severity of Permanent Magnet Synchronous Generator Based on Bearing Seat Vibration Characteristics
This paper proposes a method for using the vibration characteristics of the permanent magnet synchronous generator (PMSG) bearing seat to identify the severity of radial air-gap eccentricity (RAGE) faults. Thr...
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Article
Coexisting multi-period and chaotic attractor in fully connected system via adaptive multi-body interaction control
Multi-body interaction has been proved to exist widely in the real world. To verify the influence of multi-body interactive feedback on the dynamics of system, a novel adaptive time-delay multi-body interactio...
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Living Reference Work Entry In depth
Embolization of Metastatic Liver Disease
Cancer metastases to the liver is one of the most common causes of morbidity and mortality in many malignancies. Treatment of metastatic disease is complex, because conventional therapies used for primary tumo...
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Article
Open AccessSystematic analysis based on the cuproptosis-related genes identifies ferredoxin 1 as an immune regulator and therapeutic target for glioblastoma
Glioblastoma multiforme (GBM) is recognized as the prevailing malignant and aggressive primary brain tumor, characterized by an exceedingly unfavorable prognosis. Cuproptosis, a recently identified form of pro...
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Article
Open AccessPsychedelic concentrations of nitrous oxide reduce functional differentiation in frontoparietal and somatomotor cortical networks
Despite the longstanding use of nitrous oxide and descriptions of its psychological effects more than a century ago, there is a paucity of neurobiological investigation of associated psychedelic experiences. W...
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Article
Open AccessCurrent research and future directions of melatonin's role in seed germination
Seed germination is a complex process regulated by internal and external factors. Melatonin (N-acetyl-5-methoxytryptamine) is a ubiquitous signaling molecule, playing an important role in regulating seed germinat...
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Article
Daily runoff prediction based on the adaptive fourier decomposition method and multiscale temporal convolutional network
The non-linearity and non-stationarity of runoff series pose significant challenges to runoff forecasting, and conventional single forecasting models struggle to accurately capture the internal dynamics of the...
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Article
Open AccessA two-stage dominance-based surrogate-assisted evolution algorithm for high-dimensional expensive multi-objective optimization
In the past decades, surrogate-assisted evolutionary algorithms (SAEAs) have become one of the most popular methods to solve expensive multi-objective optimization problems (EMOPs). However, most existing meth...
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Article
Open AccessLuQi Formula relieves ventricular remodeling through improvement of HIF-1α-mediated intestinal barrier integrity
Ventricular remodeling is the adaptive process in which the heart undergoes changes due to stress, leading to heart failure (HF). The progressive decline in cardiac function is considered to contribute to inte...
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Article
Effect of the GLC Coating Thickness on the Mechanical and Tribological Properties of the CrN/GLC Coatings
The primary objective of this research is to investigate the mechanical and tribological characteristics of thin coatings that consist of graphite-like carbon (GLC) and chromium nitride (CrN). The incorporatio...
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Article
Open AccessA clustering-based competitive particle swarm optimization with grid ranking for multi-objective optimization problems
The goal of the multi-objective optimization algorithm is to quickly and accurately find a set of trade-off solutions. This paper develops a clustering-based competitive multi-objective particle swarm optimize...
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Article
Continuous voriconazole lavage in managing moderate and severe fungal keratitis: a randomized controlled trial
To assess the effectiveness and safety of continuous lavage with 1% voriconazole (CL) for moderate and severe fungal keratitis.
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Article
Source apportionment and assessment of risk to human health of soil heavy metals: a high-density sampling survey in the Dan River Basin, Shandong Province, China
The rapid development of industry, mining, and agriculture in recent years has led to heavy metal enrichment in the soil in the Dan River Basin, which has greatly threatened the land quality in this area. Howe...
