19 Result(s)
within
**qiu Xu
Life Sciences
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Article
Open AccessThe role of m6A epigenetic modifications in tumor coding and non-coding RNA processing
Epigenetic modifications of RNA significantly contribute to the regulatory processes in tumors and have, thus, received considerable attention. The m6A modification, known as N6-methyladenosine, is the predomi...
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Open AccessCorrection: Novel insights into the METTL3-METTL14 complex in musculoskeletal diseases
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Open AccessNovel insights into the METTL3-METTL14 complex in musculoskeletal diseases
N6-methyladenosine (m6A) modification, catalyzed by methyltransferase complexes (MTCs), plays many roles in multifaceted biological activities. As the most important subunit of MTCs, the METTL3-METTL14 complex is...
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Article
Associations between whole blood trace elements concentrations and HbA1c levels in patients with type 2 diabetes
Previous researches have been conducted to study the associations of trace elements on Type 2 diabetes (T2D) risk. The present study focuses on the evaluation of potential associations between trace elements a...
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Open AccessCorrection: Composite cell sheet for periodontal regeneration: crosstalk between different types of MSCs in cell sheet facilitates complex periodontal-like tissue regeneration
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Open AccessTargeting mitochondrial one-carbon enzyme MTHFD2 together with pemetrexed confers therapeutic advantages in lung adenocarcinoma
Metabolic remodeling is the fundamental molecular feature of malignant tumors. Cancer cells require sufficient energy supplies supporting their high proliferative rate. MTHFD2, a mitochondrial one-carbon metab...
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Analysis of Eight Nutrient Elements in Whole Blood of Children and Adolescents Using Inductively Coupled Plasma‐Mass Spectrometry
Few researches have been conducted on elements in whole blood of young people. Our study was to investigate the influence of age, gender and season on the contents of magnesium (Mg), calcium (Ca), iron (Fe), c...
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Reactive Oxygen Species-Responsive and Self-Illuminating Nanoparticles for Inflammation and Tumor Imaging
Reactive oxygen species (ROS) play a key role in various physiological and pathological processes. Abnormally elevated ROS levels are generally related to the pathogenesis of inflammatory diseases and tumors. ...
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Article
Emerging roles of circUBAP2 targeting miR-370-3p in proliferation, apoptosis, and invasion of papillary thyroid cancer cells
Circular RNAs (circRNAs) have been documented to be aberrantly expressed in many types of malignancies and involved in cancer progression. However, their role in thyroid cancer (TC) remains largely unknown. Ou...
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Open AccessCircular RNAs in osteoporosis: expression, functions and roles
Osteoporosis, which is caused by an imbalance in osteoblasts and osteoclasts, is a global age-related metabolic disease. Osteoblasts induce osteocyte and bone matrix formation, while osteoclasts play an import...
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Article
Open AccessAMPK activation by ASP4132 inhibits non-small cell lung cancer cell growth
Activation of adenosine monophosphate-activated protein kinase (AMPK) is able to produce significant anti-non-small cell lung cancer (NSCLC) cell activity. ASP4132 is an orally active and highly effective AMPK...
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An Improved Group Decision-Making Model for the Investment Options of Small-Scale Photovoltaic Systems Based on Cumulative Prospect Theory and Choquet Integral
With the development of photovoltaic (PV) industry, installing small-scale PV systems which are integrated into the buildings becomes popular. Therefore, it is important to make optimal investment decisions fo...
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Article
Drought stress tolerance analysis of Populus ussuriensis clones with different ploidies
The selection of drought-tolerant plants is an important aspect of plant breeding. We studied physiological and biochemical mechanisms of different ploidies of Populus ussuriensis Kom. that relate to drought stre...
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Drp1-associated mitochondrial dysfunction and mitochondrial autophagy: a novel mechanism in triptolide-induced hepatotoxicity
Triptolide being an active ingredient of Chinese herbal plant Tripterygium wilfordii Hook f. has severe hepatotoxicity. Previous studies from our lab reported triptolide-induced mitochondrial toxicity in hepatocy...
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Ectopic expression of Limonium bicolor (Bag.) Kuntze DREB (LbDREB) results in enhanced salt stress tolerance of transgenic Populus ussuriensis Kom
High salinity is one of the most common abiotic stresses that plants have to confront, and selecting salt-tolerant plants is becoming a very important task in breeding. In this study, non-transgenic (NT) and t...
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Article
Open AccessComposite cell sheet for periodontal regeneration: crosstalk between different types of MSCs in cell sheet facilitates complex periodontal-like tissue regeneration
Tissue-engineering strategies based on mesenchymal stem cells (MSCs) and cell sheets have been widely used for periodontal tissue regeneration. However, given the complexity in periodontal structure, the regen...
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Article
Characterization of Clarias gariepinus mitochondrial genome sequence and a comparative analysis with other catfishes
Clarias gariepinus is an economically important fish belonging to Siluriformes. In order to understand the characterization of catfishes, the complete mitochondrial genome sequence of the African catfish C. garie...
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Article
A Novel Wheat Related-to-Ubiquitin Gene TaRUB1 is Responsive to Pathogen Attack as Well as to Both Osmotic and Salt Stress
Protein modification by ubiquitin (Ub) and ubiquitin-like proteins (Ubls) is among the most complex and heavily investigated mechanisms of posttranslational protein regulation in eukaryotes. Moreover, Ub plays...
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Article
A novel personalized Web search model
A novel personalized Web search model is proposed. The new system, as a middleware between a user and a Web search engine, is set up on the client machine. It can learn a user’s preference implicitly and then ...
