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Article
Open AccessDispersive Fourier transform based dual-comb ranging
Laser-based light detection and ranging (LIDAR) offers a powerful tool to real-timely map spatial information with exceptional accuracy and owns various applications ranging from industrial manufacturing, and ...
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Article
Open AccessOctanoic acid mitigates busulfan-induced blood-testis barrier damage by alleviating oxidative stress and autophagy
The management of male infertility continues to encounter an array of challenges and constraints, necessitating an in-depth exploration of novel therapeutic targets to enhance its efficacy. As an eight-carbon ...
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Article
Open AccessIsolation and genetic characteristics of Novel H4N1 Avian Influenza viruses in ChongQing, China
Avian influenza viruses (AIVs) constitute significant zoonotic pathogens encompassing a broad spectrum of subtypes. Notably, the H4 subtype of AIVs has a pronounced ability to shift hosts. The escalating preva...
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Article
Dynamic evolution of information diffusion networks of news agencies in emergencies: a case study of microblogs of urban fire disasters on Sina Weibo
Critical to information diffusion, influential news agencies can publicize emergencies on social media platforms, not only hel** to guide public opinion and enhance the public’s situational awareness and res...
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Open AccessSKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation
Diabetic kidney disease (DKD) represents a microvascular complication of diabetes mellitus. Shenkang Pills (SKP), a traditional Chinese medicine formula, has been widely used in the treatment of DKD and has ob...
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Article
Open AccessNitrate stimulates adventitious rooting by increasing auxin content and regulating auxin- and root development-related genes expression in apple
Adventitious root (AR) formation is critical for cutting survival and nutrient absorption re-establishment. This complex genetic trait involves the interplay of nitrogen, endogenous hormones, and several key g...
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Open AccessProblematic mobile phone use and time management disposition in Chinese college students: the chain mediating role of sleep quality and cognitive flexibility
With the widespread adoption of smartphones, there has been a notable increase in problematic mobile phone use (PMPU), particularly prevalent among college students. Research suggests that apart from being ass...
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Open AccessHealthy lifestyle scores associate with incidence of type 2 diabetes mediated by uric acid
Whether and to what extent serum uric acid (SUA) mediates the association between combined lifestyle behaviors and type 2 diabetes mellitus (T2DM) remain unclear. This study aimed to investigate the role of SU...
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Open AccessEffects of gut microbiota on omega-3-mediated ovary and metabolic benefits in polycystic ovary syndrome mice
Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder that frequently exhibits low-grade inflammation, pro-oxidant activity, and gut dysbiosis. PCOS has become one of the leading causes ...
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Article
Open AccessCircumferential approach via dynamic position in OLIF combined with freehand screw pedicle fixation for lumbar tuberculosis requiring multilevel instrumentation: a 3-year retrospective study
To advance a modified oblique lumbar interbody fusion (M-OLIF) achieving anterior debridement and posterior freehand instrumentation simultaneously in circumferential approach via dynamic position and compare ...
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Article
Open AccessAge-related elevation of O-GlcNAc causes meiotic arrest in male mice
In recent years, the postponement of childbearing has become a critical social issue. Male fertility is negatively associated with age because of testis aging. Spermatogenesis is impaired with age, but the mol...
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Open AccessEffects of n-3 PUFA supplementation on oocyte in vitro maturation in mice with polycystic ovary syndrome
n-3 PUFAs are classic antioxidant that can be used to treat follicular dysplasia and hyperinsulinemia caused by excessive oxidative stress in PCOS women. To investigate the effect of n-3 PUFA supplementation o...
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Open Access4-Octyl itaconate attenuates glycemic deterioration by regulating macrophage polarization in mouse models of type 1 diabetes
Pancreatic beta cell dysfunction and activated macrophage infiltration are early features in type 1 diabetes pathogenesis. A tricarboxylic acid cycle metabolite that can strongly activate NF-E2-related factor ...
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Article
A global-scale framework for hydropower development incorporating strict environmental constraints
The benefits of develo** the world’s hydropower potential are intensely debated when considering the need to avoid or minimize environmental impacts. However, estimates of global unused profitable hydropower...
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Article
Open AccessSuppressive effects of pterostilbene on human cytomegalovirus (HCMV) infection and HCMV-induced cellular senescence
Human cytomegalovirus (HCMV), a member of the β-herpesvirus family, causes the establishment of a latent infection that persists throughout the life of the host and can be reactivated when immunity is weakened...
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Article
Open AccessClinical phenotypes and genetic features of hereditary transthyretin amyloidosis patients in China
Hereditary transthyretin amyloidosis (hATTR) is a progressive and fatal disease with heterogenous clinical presentations, limited diagnosis and poor prognosis. This retrospective analysis study aimed to report...
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Article
Open AccessRetraction Note to: MiR-143-3p functions as a tumor suppressor by regulating cell proliferation, invasion and epithelial–mesenchymal transition by targeting QKI-5 in esophageal squamous cell carcinoma
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12943-016-0533-3.
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Article
Rewetting global wetlands effectively reduces major greenhouse gas emissions
Carbon and nitrogen losses from degraded wetlands and methane emissions from flooded wetlands are both important sources of greenhouse gas emissions. However, the net-exchange dependence on hydrothermal condit...
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Open AccessDoubling of annual forest carbon loss over the tropics during the early twenty-first century
Previous estimates of tropical forest carbon loss in the twenty-first century using satellite data typically focus on its magnitude, whereas regional loss trajectories and associated drivers are rarely reporte...
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Article
High sensitive electrochemical detection of silver nanoparticles based on a MoS2/graphene composite
In this work, MoS2-reduced graphene oxide (rGO) composites were prepared by a simple hydrothermal reaction and characterized by SEM, Raman, XRD, and electrochemical impedance spectroscopy (EIS). The obtained MoS2