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Article
Optimization of the conditions for microwave-assisted hot-water extraction of polysaccharides from Cordyceps militaris and analysis of their hypoglycemic activity
Cordyceps militaris is recognized for its health benefits in humans. In this study, we optimized the conditions required for microwave-assisted hot-water extraction of polysaccharides isolated from Cordyceps mili...
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Article
A nearest neighbor query method for searching objects with time and location informations based on spatiotemporal similarity
It is crucial for users to find lots of information with time and geographical tags on the Internet. Therefore, a nearest neighbor query method called STR-kNN is proposed. Using the method of calculating the s...
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Chapter and Conference Paper
A Purified Stacking Ensemble Framework for Cytology Classification
Cancer is one of the fatal threats to human beings. However, early detection and diagnosis can significantly reduce death risk, in which cytology classification is indispensable. Researchers have proposed many...
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Article
From local to global: a multi-group feature enhancement network for non-uniform and dense haze removal
In the past few years, significant research on single-image dehazing has developed rapidly. Despite this effort, it is still hard to remove the dense haze completely, particularly in complex real-world cases. ...
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Article
Metabolic analysis of Schizochytrium sp. mutants with high EPA content achieved with ARTP mutagenesis screening
Eicosapentaenoic acid (EPA) belonged to the ω-3 series of polyunsaturated fatty acids and had physiological functions lipid as regulating blood lipid and preventing cardiovascular diseases. Schizochytrium sp. was...
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Article
Open AccessEffects of 10 Hz individualized repetitive transcranial magnetic stimulation on patients with disorders of consciousness: a study protocol for an exploratory double-blind crossover randomized sham-controlled trial
Repetitive transcranial magnetic stimulation (rTMS), as a non-invasive brain stimulation technique, has shown potentials for consciousness recovery of patients with disorders of consciousness (DoC), as, to a c...
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Article
Open AccessAn autoimmune pleiotropic SNP modulates IRF5 alternative promoter usage through ZBTB3-mediated chromatin loo**
Genetic sharing is extensively observed for autoimmune diseases, but the causal variants and their underlying molecular mechanisms remain largely unknown. Through systematic investigation of autoimmune disease...
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Chapter and Conference Paper
A Survey on Multimodal Named Entity Recognition
Multimodal Named Entity Recognition (MNER) is a task of identifying entities with specific semantic types from natural language text and using image information to improve the accuracy and robustness of entity...
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Article
Comparative Study of Multifunctional Irrigation-assisted Vacuum Drainage, Vacuum Sealing Drainage and the Penrose Drain in Treating Severe Multi-space Deep Fascial Infection in the Head and Neck
We aimed to compare multifunctional irrigation-assisted vacuum drainage (MIVD), vacuum sealing drainage (VSD) and the Penrose drain in treating severe multi-space deep fascial infection (DFI) in head and neck.
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Article
Inhibition of cGAS in Paraventricular Nucleus Attenuates Hypertensive Heart Injury Via Regulating Microglial Autophagy
Neuroinflammation in the cardiovascular center plays a critical role in the progression of hypertensive heart disease. And microglial autophagy is involved in the regulation of neuroinflammation. Cyclic GMP-AM...
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Article
Enantioselective [2+2]-cycloadditions with triplet photoenzymes
Naturally evolved enzymes, despite their astonishingly large variety and functional diversity, operate predominantly through thermochemical activation. Integrating prominent photocatalysis modes into proteins,...
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Article
Open AccessLCAT1 is an oncogenic LncRNA by stabilizing the IGF2BP2-CDC6 axis
Long non-coding RNAs (lncRNAs) is known to play vital roles in modulating tumorigenesis. We previously reported that LCAT1, a novel lncRNA, promotes the growth and metastasis of lung cancer cells both in vitro...
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Article
Predicting EGFR mutation status in lung adenocarcinoma presenting as ground-glass opacity: utilizing radiomics model in clinical translation
This study aimed to establish a non-invasive radiomics model based on computed tomography (CT), with favorable sensitivity and specificity to predict EGFR mutation status in GGO-featured lung adenocarcinoma su...
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Article
Open AccessDrABC: deep learning accurately predicts germline pathogenic mutation status in breast cancer patients based on phenotype data
Identifying breast cancer patients with DNA repair pathway-related germline pathogenic variants (GPVs) is important for effectively employing systemic treatment strategies and risk-reducing interventions. Howe...
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Article
Molecular subty** of diffuse gliomas using magnetic resonance imaging: comparison and correlation between radiomics and deep learning
The molecular subty** of diffuse gliomas is important. The aim of this study was to establish predictive models based on preoperative multiparametric MRI.
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Article
An adaptive enhancement algorithm based on visual saliency for low illumination images
In order to improve the brightness and contrast of low illumination color images and avoid over enhancement, an adaptive image enhancement algorithm based on visual saliency is proposed. Firstly, the original ...
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Article
Sigma-1 Receptor Activation Suppresses Microglia M1 Polarization via Regulating Endoplasmic Reticulum–Mitochondria Contact and Mitochondrial Functions in Stress-Induced Hypertension Rats
Exposure to stress plays a detrimental role in the pathogenesis of hypertension via neuroinflammation pathways. Microglial neuroinflammation in the rostral ventrolateral medulla (RVLM) exacerbates stress-induc...
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Article
Open AccessEstimated plasma volume status (ePVS) is a predictor for acute myocardial infarction in-hospital mortality: analysis based on MIMIC-III database
Estimated plasma volume status (ePVS) has been reported that associated with poor prognosis in heart failure patients. However, no researchinvestigated the association of ePVS and prognosis in patients with ac...
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Article
Visualization of lenticulostriate artery by intracranial dark-blood vessel wall imaging and its relationships with lacunar infarction in basal ganglia: a retrospective study
There is close relationship between lenticulostriate arteries (LSAs) and lacunar infarctions (LIs) of the basal ganglia. The study aims to visualize the LSAs using high-resolution vessel wall imaging (VWI) on ...
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Article
Open AccessLCAT3, a novel m6A-regulated long non-coding RNA, plays an oncogenic role in lung cancer via binding with FUBP1 to activate c-MYC
Long non-coding RNAs (lncRNAs) are important epigenetic regulators, which play critical roles in diverse physiological and pathological processes. However, the regulatory mechanism of lncRNAs in lung carcinoge...
