-
Article
Energy, exergy, and exergoeconomic cost optimization of wind-biomass multi-energy systems integrated for hydrogen production
The recent effects of climate change and rising global warming levels have increased the need to transition towards clean energy. The use of multi-energy systems is one of the potential solutions to these issu...
-
Article
The optimal diameter design of high-capacity transmission tunnels based on analysis of cable thermal effects
This study addresses a gap in previous research by thoroughly investigating the relationship between the optimal tunnel diameter and cable thermal effects in underground cable tunnels using a thermal-coupling ...
-
Article
Modeling and Deep Reinforcement Learning Based Control Parameter Tuning for Voltage Source Converter in a Renewable Energy Generation System
The fast response and low inertia characteristics of converter-based generation (CBG) lead to a new stability issue that limits renewable energy development. This is due to the fact that, using traditional con...
-
Chapter and Conference Paper
Exploring the Performance Test of Smart Substation Auxiliary Control System Test Platform Based on B/S Architecture
Smart substation is an important infrastructure for the development of the power industry, in which the auxiliary control system plays a vital role, and the performance of the auxiliary control system of smart...
-
Article
Open AccessPatient-specific iPSC-derived cardiomyocytes reveal aberrant activation of Wnt/β-catenin signaling in SCN5A-related Brugada syndrome
Mutations in the cardiac sodium channel gene SCN5A cause Brugada syndrome (BrS), an arrhythmic disorder that is a leading cause of sudden death and lacks effective treatment. An association between SCN5A and Wnt/...
-
Article
Open AccessCausal associations between thyroid cancer and IgA nephropathy: a Mendelian randomization study
The incidence of kidney disease caused by thyroid cancer is rising worldwide. Observational studies cannot recognize whether thyroid cancer is independently associated with kidney disease. We performed the Men...
-
Article
Open AccessJuxtaposing Sub-Sahara Africa’s energy poverty and renewable energy potential
Recently, the International Energy Agency (IEA) released a comprehensive roadmap for the global energy sector to achieve net-zero emission by 2050. Considering the sizeable share of (Sub-Sahara) Africa in the ...
-
Chapter and Conference Paper
Iterative Refinement for Variational Quantum Linear Solver
Variational quantum algorithms require many measurements to train parameters in their circuit to solve a given problem. If we need a highly accurate solution, the further number of measurements increases. Howe...
-
Article
Open AccessComprehensive assessment, review, and comparison of AI models for solar irradiance prediction based on different time/estimation intervals
Solar energy-based technologies have developed rapidly in recent years, however, the inability to appropriately estimate solar energy resources is still a major drawback for these technologies. In this study, ...
-
Article
Open AccessThe hypothalamus for whole-body physiology: from metabolism to aging
Obesity and aging are two important epidemic factors for metabolic syndrome and many other health issues, which contribute to devastating diseases such as cardiovascular diseases, stroke and cancers. The brain...
-
Article
Open AccessEstimated plasma volume status (ePVS) is a predictor for acute myocardial infarction in-hospital mortality: analysis based on MIMIC-III database
Estimated plasma volume status (ePVS) has been reported that associated with poor prognosis in heart failure patients. However, no researchinvestigated the association of ePVS and prognosis in patients with ac...
-
Article
Author Correction: GnRH pulse frequency and irregularity play a role in male aging
-
Article
GnRH pulse frequency and irregularity play a role in male aging
Gonadotropin-releasing hormone (GnRH) has a role in hypothalamic control of aging, but the underlying patterns and relationship with downstream reproductive hormones are still unclear. Here we report that hypo...
-
Article
Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1
Prolonged obesity is associated with cerebrovascular dysfunction; however, the underlying mechanisms remain largely unclear. In the present study, using a prolonged obesity mouse model that suffers from basila...
-
Article
Author Correction: Hypothalamic stem cells control ageing speed partly through exosomal miRNAs
The microarray data generated and analysed in this Article have been uploaded to the Gene Expression Omnibus (GEO) under accession number GSE113383. Accordin...
-
Article
Open AccessmiR199a-5p inhibits hepatic insulin sensitivity via suppression of ATG14-mediated autophagy
MicroRNAs (miRNAs) are known to contribute to many metabolic diseases, including diabetes. In this study, we investigated the role of miR199a-5p in the regulation of hepatic insulin sensitivity. Ad-anti-miR199...
-
Article
Hypothalamic stem cells control ageing speed partly through exosomal miRNAs
It has been proposed that the hypothalamus helps to control ageing, but the mechanisms responsible remain unclear. Here we develop several mouse models in which hypothalamic stem/progenitor cells that co-expre...
-
Article
Open AccessBerberine prevents progression from hepatic steatosis to steatohepatitis and fibrosis by reducing endoplasmic reticulum stress
The histological spectrum of nonalcoholic fatty liver diseases (NAFLD) ranges from hepatic steatosis to steatohepatitis and fibrosis. Berberine (BBR) is known for its therapeutic effect on obesity, hyperglycae...
-
Article
Rapid linkage of innate immunological signals to adaptive immunity by the brain-fat axis
Peripheral innate immunological signals can amplify adaptive immune responses. Cai and colleagues show that hypothalamicexposure to the cytokine TNF triggers a neural response that amplifies peripheral lymphoc...
-
Article
Metabolic learning and memory formation by the brain influence systemic metabolic homeostasis
Metabolic homeostasis is regulated by the brain, but whether this regulation involves learning and memory of metabolic information remains unexplored. Here we use a calorie-based, taste-independent learning/me...
