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Article
The effect of the tenure track on faculty member’s job insecurity and innovative work behavior
Through a survey of faculty members from 21 top research universities in China, this study analyzes the impact of the tenure reform on faculty members’ job insecurity and innovative work behavior in research. ...
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Article
Mediating Effects of Academic Self-Efficacy and Depressive Symptoms on Prosocial/Antisocial Behavior Among Youths
Adolescence is a critical period during which youth develop and shape their behaviors. Because differences between youths are strongly connected to environmental factors, we aimed to elucidate possible pathway...
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Article
Open AccessCryo-EM structure of cyanophage P-SCSP1u offers insights into DNA gating and evolution of T7-like viruses
Cyanophages, together with their host cyanobacteria, play important roles in marine biogeochemical cycles and control of marine food webs. The recently identified MPP-C (Marine Picocyanobacteria Podovirus clad...
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Article
Open AccessStructure and proposed DNA delivery mechanism of a marine roseophage
Tailed bacteriophages (order, Caudovirales) account for the majority of all phages. However, the long flexible tail of siphophages hinders comprehensive investigation of the mechanism of viral gene delivery. Here...
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Article
Pharmacokinetic Study of Conjugated Equine Estrogens in Healthy Chinese Postmenopausal Women Using a Parallel Two-Column LC–MS/MS Method
Postmenopausal women often require estrogen supplementation to improve menopausal and postmenopausal vasomotor symptoms and maintain hormonal balance. Conjugated equine estrogens extracted from the urine of pr...
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Article
Hippocampal Inhibitory Synapsis Deficits Induced by α5-Containing GABAA Receptors Mediate Chronic Neuropathic Pain–Related Cognitive Impairment
Chronic neuropathic pain often leads to cognitive impairment, but the exact mechanism remains unclear. Gamma-aminobutyric acid A receptors (GABAARs) are the major inhibitory receptors in the brain, of which the ...
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Article
Academic spin-off activities and research performance: the mediating role of research collaboration
Studies on the effect of entrepreneurial activities on scientists’ subsequent research performance have reported mixed findings. Given the misalignment between spin-off involvement and research activity, our s...
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Article
Open AccessA holistic genome dataset of bacteria, archaea and viruses of the Pearl River estuary
Estuaries are one of the most important coastal ecosystems. While microbiomes and viromes have been separately investigated in some estuaries, few studies holistically deciphered the genomes and connections of...
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Article
Open AccessEffects of Transcranial Direct Current Stimulation on effort during a working-memory task
Transcranial Direct Current Stimulation (tDCS) has shown that stimulation of Dorsolateral Prefrontal Cortex (DLPFC) facilitates task performance in working-memory tasks. However, little is known about its pote...
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Article
Open AccessPenicillin causes non-allergic anaphylaxis by activating the contact system
Immediate hypersensitivity reaction (IHR) can be divided into allergic- and non-allergic-mediated, while “anaphylaxis” is reserved for severe IHR. Clinically, true penicillin allergy is rare and most reported ...
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Article
Open AccessViral control of biomass and diversity of bacterioplankton in the deep sea
Viral abundance in deep-sea environments is high. However, the biological, ecological and biogeochemical roles of viruses in the deep sea are under debate. In the present study, microcosm incubations of deep-s...
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Article
Open AccessA newly isolated roseophage represents a distinct member of Siphoviridae family
Members of the Roseobacter lineage are a major group of marine heterotrophic bacteria because of their wide distribution, versatile lifestyles and important biogeochemical roles. Bacteriophages, the most abundant...
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Article
Open AccessImpacts of Freshwater and Seawater Mixing on the Production and Decay of Virioplankton in a Subtropical Estuary
Virioplankton is an important component of the aquatic ecosystem and plays multiple ecological and biogeochemical roles. Although the spatial and temporal distributions and dynamics of virioplankton have been ...
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Article
Rational Design of the Minimal Requirement for Helix–Helix Peptide Interactions in the Trimer-of-Hairpins Motif of Pediatric Pneumonia RSV Fusion Glycoprotein
Human respiratory syncytial virus (RSV) is a primary cause of lower respiratory tract infections and hospital visits during infancy and childhood. RSV invades host cells via a type I fusion (F) glycoprotein th...
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Article
Duration of Thermal Stability and Mechanical Properties of Mg2Si/Cu Thermoelectric Joints
Preparing an effective and long-term reliable contact between a thermoelectric (TE) element and its electrode is a key issue in integrating TE elements into practical devices. In this work, Cu electrodes were ...
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Article
Open AccessShuang-Huang-Lian injection induces an immediate hypersensitivity reaction via C5a but not IgE
Among traditional Chinese medicine injections, intravenous Shuang-Huang-Lian (IV-SHL) has the highest incidence of injection-induced immediate hypersensitivity reactions (IHRs). The precise mechanisms of IV-SH...
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Article
Open AccessShuang-Huang-Lian prevents basophilic granulocyte activation to suppress Th2 immunity
Basophilic granulocytes (BGs) not only initiate the induction of Th2 cell differentiation, but also amplify the ongoing Th2 response. Shuang-Huang-Lian (SHL) is clinically used for relieving type I hypersensit...
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Article
Fluoxetine, an Antidepressant Drug, Inhibited Cigarette Smoke-Induced Pulmonary Inflammation and Apoptosis in Rats
The present study was designed to evaluate the anti-inflammatory effect of fluoxetine (Flu) against cigarette smoke (CS)-induced chronic obstructive pulmonary disease (COPD) in rats. Forty male Sprague-Dawley ...
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Article
Open AccessIsolation and characterization of the first phage infecting ecologically important marine bacteria Erythrobacter
Erythrobacter comprises a widespread and ecologically significant genus of marine bacteria. However, no phage infecting Erythrobacter spp. has been reported to date. This study describ...
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Article
Geometry Optimization of a Segmented Thermoelectric Generator Based on Multi-parameter and Nonlinear Optimization Method
As no single thermoelectric material has presented a high figure-of-merit (ZT) over a very wide temperature range, segmented thermoelectric generators (STEGs), where the p- and n-legs are formed of different ther...
