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  1. No Access

    Article

    Pharmacokinetic Study of Conjugated Equine Estrogens in Healthy Chinese Postmenopausal Women Using a Parallel Two-Column LC–MS/MS Method

    Postmenopausal women often require estrogen supplementation to improve menopausal and postmenopausal vasomotor symptoms and maintain hormonal balance. Conjugated equine estrogens extracted from the urine of pr...

    Meiyun Shi, Lei Yin, Yantong Sun, Can Wang, Lanlan Cai… in Clinical Pharmacokinetics (2022)

  2. No Access

    Article

    Ultrahigh-throughput absolute quantitative analysis of linezolid in human plasma by direct analysis in real time mass spectrometry without chromatographic separation and its application to a pharmacokinetic study

    Therapeutic drug monitoring (TDM) is necessary in the clinical management of linezolid to improve its efficacy and reduce the risk of time- and dose-dependent toxicity. A novel and ultrahigh-throughput analyti...

    Lei Yin, Yixuan Feng, ** Tong, Zhiqiong Guo… in Analytical and Bioanalytical Chemistry (2019)

  3. No Access

    Article

    LC-MS/MS method for the quantitation of cefotetan in human plasma and its application to pharmacokinetic study

    A rapid and sensitive liquid chromatography-tandem mass spectrometry(LC-MS/MS) method for the determination of cefotetan in human plasma was developed and validated. After the protein precipitation of sample w...

    Meiyun Shi, Lei Yin, Lanlan Cai, Can Wang… in Chemical Research in Chinese Universities (2014)

  4. No Access

    Article

    LC–MS–MS Determination of Troxerutin in Plasma and Its Application to a Pharmacokinetic Study

    A highly sensitive liquid chromatography–tandem mass spectrometry (LC–MS–MS) method for the determination of troxerutin in human plasma using tramadol as internal standard (IS) has been developed and validated...

    **angyong Cui, Mengliang Zhang, **n Guan, Lei Yin, Yantong Sun… in Chromatographia (2011)