16 Result(s)
within
**nhong Guo
Science, Humanities and Social Sciences, multidisciplinary
-
Article
Open AccessIn silico designed novel multi-epitope mRNA vaccines against Brucella by targeting extracellular protein BtuB and LptD
Brucella, a gram-negative intracellular bacterium, causing Brucellosis, a zoonotic disease with a range of clinical manifestations, from asymptomatic to fever, fatigue, loss of appetite, joint and muscle pain, an...
-
Article
Forecasting the Mid-price Movements with High-Frequency LOB: A Dual-Stage Temporal Attention-Based Deep Learning Architecture
Effectively forecasting the stock mid-price movements based on Limit Order Book (LOB) data is crucial for issuing the right trade instructions in an automated trading market. The LOB data contains much valuabl...
-
Article
Open AccessRituximab treatment of adults with primary focal segmental glomerulosclerosis
To evaluate the efficacy and safety of rituximab (RTX) in the treatment of primary focal segmental glomerulosclerosis (FSGS) in adults. The clinical data of patients with primary FSGS who received RTX treatmen...
-
Article
Open AccessAssociation between quality control and outcomes of septic shock caused by intestinal perforation in China: a cross-sectional study
Septic shock, largely caused by intestinal perforation, is a common critical disease in intensive care unit (ICU). For hospitals and health systems, a performance improvement program for sepsis was strong reco...
-
Article
Open AccessResearch on an intelligent diagnosis method of mechanical faults for small sample data sets
The difficulty of feature extraction and the small sample size are two challenges in the field of mechanical fault diagnosis for a long time. Here we propose an intelligent mechanical fault diagnosis method fo...
-
Article
Open AccessDesign of a multi-epitope vaccine candidate against Brucella melitensis
Brucella is a typical facultative intracellular bacterium that can cause zoonotic infections. For Brucella, it is difficult to eliminate with current medical treatment. Therefore, a multi-epitope vaccine (MEV)...
-
Article
Open AccessHigh-precision micro-displacement sensor based on tunnel magneto-resistance effect
A high-precision micro-displacement sensor based on tunnel magneto-resistance effect is reported.We designed and simulated magnetic characteristics of the sensor, and employed chip-level Au-In bonding to imple...
-
Article
Mesoscopic Analysis of the Mechanical Properties of Beishan Granite Based on the Equivalent Crystal Model
The internal microstructure of rock has an important influence on its macroscopic mechanical properties and fracture mechanism. In this paper, an equivalent crystal model (ECM) consisting of a bonded particle ...
-
Article
Open AccessThe specific DNA barcodes based on chloroplast genes for species identification of Orchidaceae plants
DNA barcoding is currently an effective and widely used tool that enables rapid and accurate identification of plant species. The Orchidaceae is the second largest family of flowering plants, with more than 700 g...
-
Article
Open AccessRoot Physiological Traits and Transcriptome Analyses Reveal that Root Zone Water Retention Confers Drought Tolerance to Opisthopappus taihangensis
Opisthopappus taihangensis (Ling) Shih, as a relative of chrysanthemum, mainly survives on the cracks of steep slopes and cliffs. Due to the harsh environment in which O. taihangensis lives, it has evolved strong...
-
Article
Open AccessPhotoinduced semiconductor-metal transition in ultrathin troilite FeS nanosheets to trigger efficient hydrogen evolution
The exploitation of the stable and earth-abundant electrocatalyst with high catalytic activity remains a significant challenge for hydrogen evolution reaction. Being different from complex nanostructuring, thi...
-
Article
Open AccessHalf-metallic carbon nitride nanosheets with micro grid mode resonance structure for efficient photocatalytic hydrogen evolution
Photocatalytic hydrogen evolution from water has triggered an intensive search for metal-free semiconducting photocatalysts. However, traditional semiconducting materials suffer from limited hydrogen evolution...
-
Article
Open AccessLaminar Flow Attenuates Macrophage Migration Inhibitory Factor Expression in Endothelial Cells
Macrophage migration inhibitory factor (MIF) is a non-canonical cytokine that is involved in multiple inflammatory diseases, including atherosclerosis. High MIF expression found in leukocytes which facilitates...
-
Article
Open AccessHepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling
Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis, insulin resistance and a systemic pro-inflammatory response. Here we show that tumour necrosis factor receptor-associated factor...
-
Article
Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages
NDR/LATS kinase family is highly conserved from yeast to human. It remains unknown whether the members of this family function in innate immune responses. Here we demonstrate that Stk38 negatively regulates TL...
-
Article
Infective viruses produced from full-length complementary DNA of swine vesicular disease viruses HK/70 strain
The full-length cDNA clone of swine vesicular disease virus HK/70 strain named pSVOK12 was constructed in order to study the antigenicity, replication, maturation and pathogenicity of swine vesicular disease viru...
