18 Result(s)
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Article
Causal relationship between basal metabolic rate and intervertebral disc degeneration: a Mendelian randomization study
The role of basal metabolic rate (BMR) in intervertebral disc degeneration (IVDD) is still uncertain. To address this gap, we conducted a Mendelian randomization (MR) study to comprehensively explore the causa...
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Article
Open AccessCerebral blood flow changes in maintenance hemodialysis patients with restless legs syndrome and their clinical significance:a cross-sectional case-control study
Restless legs syndrome (RLS) stands as a prevalent neurological complication within maintenance hemodialysis (MHD) patients. However, the alterations in cerebral blood flow (CBF) among MHD-RLS patients remain ...
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Article
Food Effect on the Pharmacokinetics of VC004, a Tropomyosin Receptor Kinase Inhibitor: A Randomized Crossover Trial in Healthy Chinese Subjects
VC004 is a novel next-generation tropomyosin receptor kinase (TRK) inhibitor that is approved for the treatment of advanced or metastatic NTRK fusion-positive solid tumors and abrogated the drug resistance of ...
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Article
A systematic review for prevention of cisplatin-induced nephrotoxicity using different hydration protocols and meta-analysis for magnesium hydrate supplementation
Nephrotoxicity remains the most serious side effect of cisplatin therapy. Cisplatin-induced nephrotoxicity (CIN) limits the use of this drug and affects up to 20% of patients. Several possible interventions su...
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Article
Open AccessFrameless Robot-Assisted Asleep Centromedian Thalamic Nucleus Deep Brain Stimulation Surgery in Patients with Drug-Resistant Epilepsy: Technical Description and Short-Term Clinical Results
This purpose of this work is to give a detailed description of a surgical technique for frameless robot-assisted asleep deep brain stimulation (DBS) of the centromedian thalamic nucleus (CMT) in drug-resistant...
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Article
Open AccessLeft ventricular hypertrophy, carotid atherosclerosis, and cognitive impairment in peritoneal dialysis patients
Left ventricular hypertrophy (LVH) and carotid atherosclerosis (CAS) have been identified as factors associated with cognitive impairment (CI) but have not been studied in patients undergoing peritoneal dialys...
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Article
Open AccessWeipiling decoction alleviates N-methyl-N-nitro-N′-nitrosoguanidine-induced gastric precancerous lesions via NF-κB signalling pathway inhibition
We aimed to explore how weipiling (WPL) decoction WPL alleviates gastric precancerous lesions (GPLs) and uncover its anti-inflammatory roles in GPL treatment.
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Article
Open AccessThe emerging role of neutrophilic extracellular traps in intestinal disease
Neutrophil extracellular traps (NETs) are extracellular reticular fibrillar structures composed of DNA, histones, granulins and cytoplasmic proteins that are delivered externally by neutrophils in response to ...
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Article
Open AccessA clinical and biomechanical comparison of INFIX plus single versus double sacroiliac screw fixation for unstable pelvic ring injury
The aim of this study is to compare the clinical and biomechanical outcome of INFIX plus single with two sacroiliac screw fixation for unstable pelvic fractures of Type C.
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Article
Open AccessCorrection to: Study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction
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Article
Open AccessStudy on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction
Drug-coated balloon (DCB) is a new technology that has emerged in recent years and has been proven to be effective and safe in the treatment of in-stent restenosis. The purpose of this article is to observe th...
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Article
Open AccessCirc-SPG11 knockdown hampers IL-1β-induced osteoarthritis progression via targeting miR-337-3p/ADAMTS5
Osteoarthritis (OA) is responsible for the impotent disability in old people. Circular RNA (circRNA) has been reported to be related to the development of diseases. The lack of research on the role of circRNA ...
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Article
Open AccessKetogenic diet alleviates colitis by reduction of colonic group 3 innate lymphoid cells through altering gut microbiome
Accumulating evidence suggests that ketogenic diets (KDs) mediate the rise of circulating ketone bodies and exert a potential anti-inflammatory effect; however, the consequences of this unique diet on colitis ...
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Article
Open AccessLimb ischemic preconditioning ameliorates renal microcirculation through activation of PI3K/Akt/eNOS signaling pathway after acute kidney injury
Contrast-induced acute kidney injury (CI-AKI) resulting from administration of iodinated contrast media (CM) is the third leading cause of hospital-acquired acute kidney injury and is associated with substanti...
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Article
Platelet–lymphocyte ratio as a potential prognostic factor in gynecologic cancers: a meta-analysis
Cancer-related inflammation plays an important role in tumor development and progression. Platelet–lymphocyte ratio (PLR) has been studied as a biomarker for prognosis in gynecologic cancers. But, the results ...
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Article
Intraparenchymal epidermoid cyst: proper surgical management may lead to satisfactory outcome
Intraparenchymal epidermoid cysts (IECs) are rare lesions, thus the preoperative diagnosis and proper surgical management are still a challenge. We searched the database at our institution and performed a sear...
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Article
Open AccessLeft ventricular diastolic dysfunction in nonhuman primate model of dysmetabolism and diabetes
Diabetes is one of the major risk factors for cardiomyopathy and heart failure with reduced ejection fraction (EF) and highly associated with left ventricular (LV) dysfunction in human. This study aimed 1) to ...
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Chapter and Conference Paper
Preliminary Design Method Study for the Space Deployable Articulated Mast
The Space deployable articulated mast work theory and its main application field are specified. The primary performance parameters which can represent the mast performance have been put forward. And the perfor...
