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Article
Nanodiamond: a promising metal-free nanoscale material in photocatalysis and electrocatalysis
Benefiting from its surface-rich functional groups, eco-friendliness, impressive electrochemical properties, excellent light absorption, structural tunability at the atomic/morphological level, and ultra-high ...
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Article
Open AccessEffect of Flammulina velutipes polysaccharide on mitochondrial apoptosis in lung adenocarcinoma A549 cells
FVP is a polysaccharide extracted from Flammulina velutipes with immunomodulatory, anti-tumor, and anti-oxidation activities. In this study, we obtained the crude polysaccharide FVP-C from the water extract of Fl...
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Article
Potential Plausible Role of Stem Cell for Treating Depressive Disorder: a Retrospective Review
Depression poses a significant threat to global physical and mental health, impacting around 3.8% of the population with a rising incidence. Current treatment options primarily involve medication and psycholog...
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Article
Open AccessMiR-223 enhances lipophagy by suppressing CTSB in microglia following lysolecithin-induced demyelination in mice
Lipid droplet (LD)-laden microglia is a key pathological hallmark of multiple sclerosis. The recent discovery of this novel microglial subtype, lipid-droplet-accumulating microglia (LDAM), is notable for incre...
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Article
Open AccessEffects of percutaneous endovascular angioplasty for severe stenosis or occlusion of subclavian artery
To investigate the effect and safety of percutaneous endovascular angioplasty (PEA) with optional stenting for the treatment of severe stenosis or occlusion of subclavian artery, patients with severe stenosis ...
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Article
Publisher Correction: E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1
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Article
Recent advances in glycerol valorization through electrocatalytic methods
The recent tremendous growth of biodiesel production from vegetable oils or waste fats has led to increased glycerol accumulation as a by-product of this process. This sparked attention towards glycerol use an...
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Article
Influence of pier height on the safety of trains running on high-speed railway bridges during earthquakes
Sudden earthquakes pose a threat to the running safety of trains on high-speed railway bridges, and the stiffness of piers is one of the factors affecting the dynamic response of train-track-bridge system. In ...
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Article
T cell-redirecting antibody for treatment of solid tumors via targeting mesothelin
T cell engaging bispecific antibodies (TCBs) have recently become significant in cancer treatment. In this study we developed MSLN490, a novel TCB designed to target mesothelin (MSLN), a glycosylphosphatidylin...
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Article
Open AccessDevelopment and validation of a prognostic model for assessing long COVID risk following Omicron wave—a large population-based cohort study
Long coronavirus disease (COVID) after COVID-19 infection is continuously threatening the health of people all over the world. Early prediction of the risk of Long COVID in hospitalized patients will help clin...
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Article
Targeting metabolism to enhance immunotherapy within tumor microenvironment
Cancer metabolic reprogramming has been considered an emerging hallmark in tumorigenesis and the antitumor immune response. Like cancer cells, immune cells within the tumor microenvironment or premetastatic ni...
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Article
Open AccessMolecular orbital breaking in photo-mediated organosilicon Schiff base ferroelectric crystals
Ferroelectric materials, whose electrical polarization can be switched under external stimuli, have been widely used in sensors, data storage, and energy conversion. Molecular orbital breaking can result in sw...
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Article
CircNSD1 promotes cardiac fibrosis through targeting the miR-429-3p/SULF1/Wnt/β-catenin signaling pathway
Cardiac fibrosis is a detrimental pathological process, which constitutes the key factor for adverse cardiac structural remodeling leading to heart failure and other critical conditions. Circular RNAs (circRNA...
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Article
E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1
The circadian clock is the inner rhythm of life activities and is controlled by a self-sustained and endogenous molecular clock, which maintains a ~ 24 h internal oscillation. As the core element of the circad...
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Article
Correction to: Efects of Manganese and Iron, Alone or in Combination, on Apoptosis in BV2 Cells
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Article
Robot-assisted versus laparoscopic-assisted gastrectomy among malnourished patients with gastric cancer based on textbook outcome
Textbook outcome (TO) has been widely employed as a comprehensive indicator to assess the short-term prognosis of patients with cancer. Preoperative malnutrition is a potential risk factor for adverse surgical...
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Article
Long-term oncological outcomes of 3D versus 2D laparoscopic gastrectomy for gastric cancer: a randomized clinical trial
Laparoscopy-assisted gastrectomy (LG) is rapidly gaining popularity owing to its minimal invasiveness. Previous studies have found that compared with two-dimensional (2D)-LG, three-dimensional (3D)-LG showed b...
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Article
Effects of Manganese and Iron, Alone or in Combination, on Apoptosis in BV2 Cells
The aim of study was to address the effects of manganese and iron, alone and in combination, on apoptosis of BV2 microglia cells, and to determine if combined exposure to these metals augments their individual...
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Article
Open AccessLactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model
Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism. Although recent studies have noted a relationship between the gut microbiota and gout, whether the microbiota could ameliorate ...
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Article
Interfacial reaction between AZ91D magnesium alloy melt and mild steel under high temperature
The metallurgical quality control of magnesium (Mg) and Mg alloys in melting process is required to ensure a satisfied mechanical and corrosion performance, while the typical used steel crucible introduces imp...
