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1,549 Result(s)
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Article
Changes of gut microbiota diversity and stability over the reproduction process in captive female Gentoo penguins (Pygoscelis papua)
Homeostasis of gut microbiota is critical for growth and health of animals. However, the impact of reproduction on penguin gut microbiota remains unclear, despite penguins being sentinel species of the marine ...
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Open AccessGenome-wide analysis of the family 10 plant pathogenesis-related proteins in Pyrus bretschneideri and functional analysis of PbrMLP for Colletotrichum fructicola resistance
Pathogenesis-related (PR) genes are key regulators of plant adaptation responses to biotic and abiotic stresses. Family 10 PRs (PR10s, also known as major latex proteins) are usually induced by pathogens and envi...
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Open AccessALKBH5 regulates chicken adipogenesis by mediating LCAT mRNA stability depending on m6A modification
Previous studies have demonstrated the role of N6-methyladenosine (m6A) RNA methylation in various biological processes, our research is the first to elucidate its specific impact on LCAT mRNA stability and adipo...
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Introgression of chromosome 5P from Agropyron cristatum enhances grain weight in a wheat background
A grain weight locus from Agropyron cristatum chromosome 5P increases grain weight in different wheat backgrounds and is localized to 5PL (bin 7–12).
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Open AccessA multi-kingdom collection of 33,804 reference genomes for the human vaginal microbiome
The human vagina harbours diverse microorganisms—bacteria, viruses and fungi—with profound implications for women’s health. Genome-level analysis of the vaginal microbiome across multiple kingdoms remains limi...
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Optimization of Preparation Technology of Purple Yam Slices by Response Surface Methodology and Study of Its Antioxidant Activity
Aiming at the problems of perishable lesions during storage and nutrients loss during high temperature processing of fresh purple yam, this study was to optimize the processing technology of purple yam slices ...
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Open AccessAssociation between indicators of visceral lipid accumulation and infertility: a cross-sectional study based on U.S. women
Evidence on the association between visceral lipid accumulation and infertility remains limited and controversial. Therefore, the current investigation is the first investigation to unveil this correlation by ...
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Open AccessIntegrated transcriptomic and metabolomic analysis provides insight into the pollen development of CMS-D1 rice
Cytoplasmic male sterility (CMS) has greatly improved the utilization of heterosis in crops due to the absence of functional male gametophyte. The newly developed sporophytic D1 type CMS (CMS-D1) rice exhibits...
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Open AccessN6-methyladenosine-driven miR-143/145-KLF4 circuit orchestrates the phenotypic switch of pulmonary artery smooth muscle cells
Pulmonary hypertension (PH) is characterized by vascular remodeling predominantly driven by a phenotypic switching in pulmonary artery smooth muscle cells (PASMCs). However, the underlying mechanisms for this ...
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Open AccessInhibition of fatty acid uptake by TGR5 prevents diabetic cardiomyopathy
Diabetic cardiomyopathy is characterized by myocardial lipid accumulation and cardiac dysfunction. Bile acid metabolism is known to play a crucial role in cardiovascular and metabolic diseases. Takeda G-protei...
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Exploring the effects of different fertilizer application durations on the functional microbial profiles of soil carbon and nitrogen cycling by using metagenomics in Paulownia plantations in a subtropical zone
Paulownia fortunei, one of the world’s fastest growing timber tree species, is universally applied with fertilizer as a management approach to meet the nutrient requirements for efficient cultivation. The substan...
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On the use of EST-SSR to analysis the genetic diversity of segetale rye from China
A weedy rye, Secale cereale subsp. segetale found in **njiang, China, possess strong stress tolerance, tillering capacity and many useful traits. The study aims to better understand the genetic diversity of seget...
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Optimizing fertilization depth can promote sustainable development of dryland agriculture in the Loess Plateau region of China by improving crop production and reducing gas emissions
Fertilization methods have affected the development of dryland agriculture. There is a need to understand the impacts of different fertilizer application depths on crop production and gas emissions to facilita...
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Effects of Probiotic Enterococcus faecium from Yak on the Intestinal Microflora and Metabolomics of Mice with Salmonella Infection
Salmonella spp. are pathogenic bacteria that cause diarrhea, abortion, and death in yak and severely harm livestock breeding. Therefore, it is vital to identify a probiotic that effectively antagonizes Salmonella
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Open AccessCurrent applications of intestinal organoids: a review
In the past decade, intestinal organoid technology has paved the way for reproducing tissue or organ morphogenesis during intestinal physiological processes in vitro and studying the pathogenesis of various in...
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Genome-wide elucidation and expression features of Q-type C2H2 zinc finger protein gene family in Rhododendron henanense subsp. lingbaoense
In plants, the C2H2 zinc-finger (C2H2-ZF) gene family is involved in various aspects of growth, development, and stress resistance. However, to date, no genome-wide identification, characterization, and expres...
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Open AccessComparison of allo-SCT, auto-SCT and chemotherapy for the treatment of patients with low- or intermediate-risk acute myeloid leukemia: a network meta-analysis
The therapeutic status of allogeneic stem cell transplantation (allo-SCT) as a post-remission treatment for patients with high-risk acute myeloid leukemia (AML) was well-accepted. However, the optimal treatmen...
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Open AccessLipotoxic hepatocyte derived LIMA1 enriched small extracellular vesicles promote hepatic stellate cells activation via inhibiting mitophagy
Hepatic stellate cells (HSCs) play a crucial role in the development of fibrosis in non-alcoholic fatty liver disease (NAFLD). Small extracellular vesicles (sEV) act as mediators for intercellular information ...
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Open AccessAlleles on locus chromosome 4B from different parents confer tiller number and the yield-associated traits in wheat
Pleiotropy is frequently detected in agronomic traits of wheat (Triticum aestivum). A locus on chromosome 4B, QTn/Ptn/Sl/Sns/Al/Tgw/Gl/Gw.caas-4B, proved to show pleiotropic effects on tiller, spike, and grain tr...
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Open AccessIn vivo rescue of genetic dilated cardiomyopathy by systemic delivery of nexilin
Dilated cardiomyopathy (DCM) is one of the most common causes of heart failure. Multiple identified mutations in nexilin (NEXN) have been suggested to be linked with severe DCM. However, the exact association ...