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Article
Willingness to Use Long-Acting Injectable Cabotegravir and Associated Factors Among Men Who Have Sex with Men in Guangxi, China
Cabotegravir (CAB-LA), the first long-acting injectable pre-exposure prophylaxis (PrEP), has been approved for use in the USA and is not currently on the market in China. However, willingness to use CAB-LA and...
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Article
Transcriptome-wide analysis of a superior xylan degrading isolate Penicillium oxalicum 5–18 revealed active lignocellulosic degrading genes
Lignocellulose biomass raw materials have a high value in energy conversion. Recently, there has been growing interest in using microorganisms to secret a series of enzymes for converting low-cost biomass into...
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Article
Open AccessTranscending membrane barriers: advances in membrane engineering to enhance the production capacity of microbial cell factories
Microbial cell factories serve as pivotal platforms for the production of high-value natural products, which tend to accumulate on the cell membrane due to their hydrophobic properties. However, the limited sp...
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Article
Effects of the Rolling Temperature on the Microstructure Uniformities and Mechanical Properties of Large 2219 Al–Cu Alloy Rings
The microstructure uniformities and mechanical properties of the 2219 Al–Cu alloy ring should be further improved. By whole-process analysis and partial quantitative analysis, this paper studies the microstruc...
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Article
Open AccessExpert consensus on pediatric orthodontic therapies of malocclusions in children
Malocclusion, identified by the World Health Organization (WHO) as one of three major oral diseases, profoundly impacts the dental-maxillofacial functions, facial esthetics, and long-term development of ~260 m...
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Article
The p-Laplacian overdetermined problem on Riemannian manifolds
In this paper, we study the overdetermined problem for the p-Laplacian equation on complete noncompact Riemannian manifolds with nonnegative Ricci curvature. We prove that the regularity results of weak solutions...
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Article
Open AccessSynergistic dual cell therapy for atherosclerosis regression: ROS-responsive Bio-liposomes co-loaded with Geniposide and Emodin
The development of nanomaterials for delivering natural compounds has emerged as a promising approach for atherosclerosis therapy. However, premature drug release remains a challenge. Here, we present a ROS-re...
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Article
Anatomical and immunohistochemical analyses of the fusion of the premaxillary–maxillary suture in human fetuses
The development of the premaxillary–maxillary suture (PMS) in human fetuses and a possible association between the fusion time of the PMS and maxillary deficiency were investigated. Expression of transforming ...
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Article
How Do Coalitions Break Down? An Alternative View
We propose an alternative dynamic theory of coalition breakdown. Motivated by recent coalition-splitting events of unilateral country withdrawals, we assume that: (i) the payoff-sharing rule within coalitions ...
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Article
Optimal lockdown and vaccination policies to contain the spread of a mutating infectious disease
We develop a piecewise deterministic control model to study optimal lockdown and vaccination policies to manage a pandemic. Lockdown is modeled as an impulse control that allows the decision maker to switch fr...
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Article
Controllable synthesis of uniform flower-shaped covalent organic framework microspheres as absorbent for solid-phase extraction of trace 2,4-dichlorophenol
Controllable synthesis of micro-flower covalent organic frameworks (MFCOFs) with controllable size, monodisperse, spherical, and beautiful flower shape was realized by using 2,5-diformylfuran (DFF) and p-pheny...
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Article
Open AccessHIV transmission and associated factors under the scale-up of HIV antiretroviral therapy: a population-based longitudinal molecular network study
To evaluate the prevention efficacy of scaling up HIV/AIDS antiretroviral therapy (ART) on HIV transmission at the population level and determine associated factors of HIV secondary transmission.
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Article
Open AccessFerroptosis in epithelial ovarian cancer: a burgeoning target with extraordinary therapeutic potential
Epithelial ovarian cancer (EOC) is universally acknowledged as a terrifying women killer for its high mortality. Recent research advances support that ferroptosis, an emerging iron-dependent type of regulated ...
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Article
Effects of soil fauna on leaf litter decomposition and nutrient release during a two-year field experiment in a poplar plantation
Soil fauna play a key role in the litter decomposition process in two ways; directly via fragmentation and consumption of the litter, and indirectly through changes in soil structure and the activity of microo...
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Article
Open AccessAuthor Correction: The lead time and geographical variations of Baidu Search Index in the early warning of COVID-19
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Article
Open AccessThe lead time and geographical variations of Baidu Search Index in the early warning of COVID-19
Internet search data was a useful tool in the pre-warning of COVID-19. However, the lead time and indicators may change over time and space with the new variants appear and massive nucleic acid testing. Since ...
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Article
Featured immune characteristics of COVID-19 and systemic lupus erythematosus revealed by multidimensional integrated analyses
Coronavirus disease 2019 (COVID-19) shares similar immune characteristics with autoimmune diseases like systemic lupus erythematosus (SLE). However, such associations have not yet been investigated at the sing...
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Article
Soil radiocarbon abundance in global forest ecosystems controlled by climate and soil properties
Soil is the largest carbon pool on land. A small proportional change of soil carbon may lead to strong feedback to the climate system. However, how climate and soil properties affect soil carbon storage at reg...
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Article
Open AccessIndole-3-propionic acid alleviates sepsis-associated acute liver injury by activating pregnane X receptor
The morbidity and mortality of sepsis are extremely high, which is a major problem plaguing human health. However, current drugs and measures for the prevention and treatment of sepsis have little effect. Seps...
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Article
Open AccessAnti-PD-1 therapy achieves favorable outcomes in HBV-positive non-liver cancer
Anti-PD-1 therapy has shown promising outcomes in the treatment of different types of cancer. It is of fundamental interest to analyze the efficacy of anti-PD-1 therapy in cancer patients infected with hepatit...
