17,283 Result(s)
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**gyi **ao
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Open AccessAssociations of plasma proteomics and age-related outcomes with brain age in a diverse cohort
Machine learning models are increasingly being used to estimate “brain age” from neuroimaging data. The gap between chronological age and the estimated brain age gap (BAG) is potentially a measure of accelerat...
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Open AccessResveratrol activates autophagy and protects from UVA-induced photoaging in human skin fibroblasts and the skin of male mice by regulating the AMPK pathway
Skin photoaging is mostly caused by ultraviolet A (UVA), although active medications to effectively counteract UVA-induced photoaging have not yet been created. Resveratrol, a naturally occurring polyphenol fo...
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METTL3-modified lncRNA DSCAM-AS1 promotes breast cancer progression through inhibiting ferroptosis
Numerous studies have indicated that N6-methyladenosine (m6A) and lncRNAs play pivotal roles in human cancer. However, the underlying functions and mechanisms of m6A-lncRNA in the physiological processes of breas...
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Model analysis and application case for complex multi-system evolutionary optimization
A complex system is made up of multiple related and coupled subsystems. Each subsystem has its own set of multiple constraints and objectives, and is commonly found in real-world applications. Biogeography-bas...
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Enhanced Photocatalytic Activity of Z-scheme Meso-BiVO4-Au-CdS for Degradation of Rhodamine B
We synthesized BiVO4 mesocrystals with ordered assembly structure, and studied the structural order and the relationship between the photodegradation of Rhodamine B. Au nanoparticles (NPs) were successfully loade...
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A positional-aware attention PCa detection network on multi-parametric MRI
Prostate cancer (PCa) is the most prevalent cancer among the males. PCa detection based on multi-parametric magnetic resonance imaging (mpMRI) can provide precise target points for puncture robots to enhance t...
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Effects of the length of frozen rivulets on the flow field structures and the aerodynamic performance of an airfoil
Runback ice can lead to significant aerodynamic deterioration and affects aircraft flight safety. The frozen rivulets can form during the aircraft icing process as a part of the runback ice. So far, the effect...
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Open AccessJWH-182: a safe and effective synthetic cannabinoid for chemotherapy-induced neuropathic pain in preclinical models
Chemotherapy-induced neuropathic pain (CINP), a condition with unmet treatment needs, affects over half of cancer patients treated with chemotherapeutics. Researchers have recently focused on the endocannabino...
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Open AccessExamining the determinants of food waste behavior in China at the consumer level
Food loss and waste are global problems for food security, as one-third of all food produced globally does not reach the consumer’s table. These numbers seem unreasonable when the data presented by the Food an...
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The aneurysm occlusion and recurrence of posterior communicating artery aneurysms following the treatment with the pipeline embolization device
Despite advancements in treatment modalities such as flow diverters, the optimal management of posterior communicating artery (PComA) aneurysms remains uncertain. While PComA aneurysms treated with the Pipelin...
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Open AccessB3galt5 functions as a PXR target gene and regulates obesity and insulin resistance by maintaining intestinal integrity
Pregnane X receptor (PXR) has been reported to regulate glycolipid metabolism. The dysfunction of intestinal barrier contributes to metabolic disorders. However, the role of intestinal PXR in metabolic disease...
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Open AccessPDX1+ cell budding morphogenesis in a stem cell-derived islet spheroid system
Remarkable advances in protocol development have been achieved to manufacture insulin-secreting islets from human pluripotent stem cells (hPSCs). Distinct from current approaches, we devised a tunable strategy...
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H2S activates succinate dehydrogenase through persulfidation to induce stomatal closure in Arabidopsis
Recent studies have demonstrated that hydrogen sulfide (H2S), an important gasotransmitter, participates in stomatal closure and is associated with the regulation of cellular bioenergetics. However, the coupling ...
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Application of GWAS summary data and drug-induced gene expression profiles of neural progenitor cells in psychiatric drug prioritization analysis
Common psychiatric disorders constitute one of the most substantial healthcare burdens worldwide. However, drug development in psychiatry remains hampered partially due to the lack of approaches to estimating ...
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HyperMatch: long-form text matching via hypergraph convolutional networks
Semantic text matching plays a vital role in diverse domains, such as information retrieval, question answering, and recommendation. However, longer texts present challenges, including noise, long-range depend...
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Open AccessEffect of Tronclass combined with team-based learning on nursing students’ self-directed learning and academic performance: a pretest-posttest study
Self-directed learning ability is crucial for lifelong learning. The inadequate self-directed learning ability of nursing students in China may be due to their deficiency in self-management or learning initiat...
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Open AccessDevelopment of implantable electrode based on bioresorbable Mg alloy for tissue welding application
An implantable electrode based on bioresorbable Mg-Nd-Zn-Zr alloy was developed for next-generation radiofrequency (RF) tissue welding application, aiming to reduce thermal damage and enhance anastomotic stren...
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Open AccessControversy between biopsy and risk in children with proteinuria: is there a paradigm war?
Proteinuria is a prevalent symptom of pediatric nephrology, while kidney biopsy remains the gold standard for kidney tissue analysis, and it is currently controversial. We report the rare case that the mutatio...
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Open AccessZinc finger transcription factor ZFP1 is associated with growth, conidiation, osmoregulation, and virulence in the Polygonatum kingianum pathogen Fusarium oxysporum
Rhizome rot is a destructive soil-borne disease of Polygonatum kingianum and adversely affects the yield and sustenance of the plant. Understanding how the causal fungus Fusarium oxysporum infects P. kingianum ma...
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Salinity-driven nitrogen removal and bacteria community compositions in microbial fuel cell–integrated constructed wetlands
The effects of salinity gradients (500–4000 mg·L−1 NaCl) on electricity generation, nitrogen removal, and microbial community were investigated in a constructed wetland-microbial fuel cell (CW-MFC) system. The re...
