-
Article
Association of ever use of e-cigarettes with health and lifestyle variables among young adults: a Canadian health measure survey study
Research suggests that va** raises oxidative stress levels and has been implicated in poor mental health. The objective of this study is to assess cross-sectional associations between quality of life (QOL) i...
-
Article
Comparison of different sources of mesenchymal stem cells: focus on inflammatory bowel disease
Inflammatory bowel disease (IBD) poses a significant challenge in modern medicine, with conventional treatments limited by efficacy and associated side effects, necessitating innovative therapeutic approaches....
-
Article
Open AccessRotenone activates the LKB1-AMPK-ULK1 signaling pathway to induce autophagy and apoptosis in rat thoracic aortic endothelial cells
The specific mechanism by which rotenone impacts thoracic aortic autophagy and apoptosis is unknown. We aimed to investigate the regulatory effects of rotenone on autophagy and apoptosis in rat thoracic aortic...
-
Article
Open AccessGrowth of millimeter-sized 2D metal iodide crystals induced by ion-specific preference at water-air interfaces
Conventional liquid-phase methods lack precise control in synthesizing and processing materials with macroscopic sizes and atomic thicknesses. Water interfaces are ubiquitous and unique in catalyzing many chem...
-
Article
Open AccessAssociation of factors with childhood asthma and allergic diseases using latent class analysis
We hypothesize that children characterized by deprived factors have poorer health outcomes. We aim to identify clustering of determinants and estimate risk of early childhood diseases. This 1993–2019 longitudi...
-
Article
Open AccessModulation of neural gene networks by estradiol in old rhesus macaque females
The postmenopausal decrease in circulating estradiol (E2) levels has been shown to contribute to several adverse physiological and psychiatric effects. To elucidate the molecular effects of E2 on the brain, we...
-
Article
Open AccessMechanistic insight into the competition between interfacial and bulk reactions in microdroplets through N2O5 ammonolysis and hydrolysis
Reactive uptake of dinitrogen pentaoxide (N2O5) into aqueous aerosols is a major loss channel for NOx in the troposphere; however, a quantitative understanding of the uptake mechanism is lacking. Herein, a comput...
-
Article
Rich proton dynamics and phase behaviours of nanoconfined ices
Water confined in nanopores is ubiquitous in geological, planetary and biological environments and in nanofluidic settings. Understanding the phase behaviour and proton dynamics of nanoconfined water under hig...
-
Article
Open AccessSynergism of non-thermal plasma and low concentration RSL3 triggers ferroptosis via promoting xCT lysosomal degradation through ROS/AMPK/mTOR axis in lung cancer cells
Though (1S, 3R)-RSL3 has been used widely in basic research as a small molecular inducer of ferroptosis, the toxicity on normal cells and poor pharmacokinetic properties of RSL3 limited its clinical applicatio...
-
Article
Open AccessExogenous carbon monoxide promotes GPX4-dependent ferroptosis through ROS/GSK3β axis in non-small cell lung cancer
The gas therapy is drawing increasing attention in the treatment of many diseases including cancer. As one of gas signaling molecules, carbon monoxide (CO) has been proved to exert anti-cancer effects via trigger...
-
Chapter and Conference Paper
Efficiency Analysis of Advanced Treatment Process and Upgrading Reconstruction of Urban Sewage Treatment Plant
To analyze the efficiency of different advanced treatment processes of sewage treatment plants, two sewage treatment plants with improved A2/O as the secondary treatment process but with different advanced treatm...
-
Article
Role of Serum/Glucocorticoid-Regulated Kinase 1 (SGK1) in Immune and Inflammatory Diseases
Serum/glucocorticoid-regulated kinase 1 (SGK1), a member of the serine/threonine protein kinase gene family, is primarily regulated by serum and glucocorticoids. SGK1 is involved in the development of tumors and ...
-
Article
In vitro and in vivo study on the treatment of non-small cell lung cancer with radionuclide labeled PD-L1 nanobody
Nanobodies have become promising carriers due to excellent in vivo properties. Radiopharmaceutical therapy targeting programmed cell death ligand 1 (PD-L1) is an effective therapeutic strategy. Our study aimed...
-
Article
Tumor budding as an indicator for lymph node metastasis and prognosis of early gastric cancer
Tumor budding, considered as an independent risk factor reflecting prognosis of some malignant tumors, has been recognized as an important clinicopathological indicator of colorectal carcinoma. However, the ev...
-
Article
Open AccessOily fish and raw vegetable consumption can decrease the risk of AQP4-positive neuromyelitis optica spectrum disorders: a Mendelian-randomization study
Neuromyelitis optica spectrum disorders (NMOSD) are severe inflammatory disorders of the central nervous system targeting aquaporin‐4 (AQP4). The risk factors for NMOSD remain to be determined, though they may...
-
Article
Open AccessCorrection: Dynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028)
-
Chapter and Conference Paper
Dispatch Strategy for Transmission Overload Based on Safe Reinforcement Learning
Active power dispatch is one of the major operation tasks for power system that keeps the power generation and consumption in a real-time balance. Real-time decisions for active power dispatch can be seen as a...
-
Article
Inverse Problem for a Mathematical Model of Sorption Dynamics with a Variable Kinetic Coefficient
The authors consider an inverse problem for a nonlinear mathematical model of sorption dynamics with an unknown variable kinetic coefficient. The theorem of existence of a solution to the inverse problem is pr...
-
Article
Moderate-Severe White Matter Lesion Predicts Delayed Intraventricular Hemorrhage in Intracerebral Hemorrhage
Most existing studies have focused on the correlation between white matter lesion (WML) and baseline intraventricular hemorrhage (IVH) in patients with intracerebral hemorrhage (ICH), whereas few studies have ...
-
Article
Open AccessDynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028)
Due to the blood-brain barrier, plasma is not an ideal source to evaluate the genetic characteristics of central nervous system tumors. Thus, cerebrospinal fluid (CSF) is becoming an alternative biopsy type to...