33 Result(s)

Article

Identification of metabolism-related key genes as potential biomarkers for pathogenesis of immune thrombocytopenia

Immune thrombocytopenia (ITP), an acquired autoimmune disease, is characterized by immune-mediated platelet destruction. A biomarker is a biological entity that contributes to disease pathogenesis and reflects...

**angmei Xu, Jiamin Zhang, Hongyun **ng, Liying Han, **aoming Li… in Scientific Reports (2024)

Article

Screening and verification of hub genes in esophageal squamous cell carcinoma by integrated analysis

Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors. However, the mechanisms underlying ESCC tumorigenesis have not been fully elucidated. Thus, we aimed to determine the key g...

Hongqiang Wu, Peiyao Zhu, Peng Shu, Shuguang Zhang in Scientific Reports (2024)

Article

Safety and feasibility of anti-CD19 CAR T cells expressing inducible IL-7 and CCL19 in patients with relapsed or refractory large B-cell lymphoma

Although CD19-specific chimeric antigen receptor (CAR) T cells are curative for patients with relapsed or refractory large B-cell lymphoma (R/R LBCL), disease relapse with tumor antigen-positive remains a chal...

Wen Lei, Ai Zhao, Hui Liu, Chunmei Yang, Cheng Wei, Shanshan Guo… in Cell Discovery (2024)

Article

DTX2 promotes glioma development via regulation of HLTF

Human Deltex 2 (DTX2) is a ubiquitin E3 ligase that functions as an oncogene and has been shown to participate in many human cancers. However, the role of DTX2 in glioma progression has remained obscure. In th...

Ren Li, Yang Chen, Biao Yang, Ziao Li, Peize Li, Yu Chen, Jiayu Li… in Biology Direct (2024)

Article

Evaluation of the efficacy of Biejia decoction pill combined with entecavir in the treatment of hepatitis B liver fibrosis/cirrhosis by VCTE

The vibration controlled transient elastography (VCTE) technique was used to assess the effectiveness of a Biejia Decoction pill in combination with Entecavir in the treatment of hepatitis B liver fibrosis/cir...

Lijun Wan, Chungen Hu, Fenfen Wang, Kedong Xu, Fan Li, Bo He… in Scientific Reports (2023)

Article

Author Correction: Research on Homogeneity and Service Performance under the Liquid Core Forging Process

Yongqiang Wu, Yongshan Wang, Kaikun Wang… in Metallography, Microstructure, and Analysis (2023)

Article

Tyrosine-kinase inhibitor combined with iodine-125 seed brachytherapy for hepatocellular carcinoma refractory to transarterial chemoembolization: a propensity-matched study

To investigate the efficacy and safety of tyrosine-kinase inhibitor (TKI) combined with iodine-125 seed brachytherapy (TKI-I) versus TKI alone for patients with hepatocellular carcinoma (HCC) refractory to tra...

Yongjian Guo, **gqiang Wu, Licong Liang, Kangshun Zhu, **gwen Zhou… in Cancer Imaging (2023)

Article

Stromal cells in the tumor microenvironment: accomplices of tumor progression?

The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cel...

Yan Zhao, Meili Shen, Liangqiang Wu, Haiqin Yang, Yixuan Yao… in Cell Death & Disease (2023)

Article

High-quality chromosome-level de novo assembly of the Trifolium repens

White clover (Trifolium repens L.), an excellent perennial legume forage, is an allotetraploid native to southeastern Europe and southern Asia. It has high nutritional, ecological, genetic breeding, and medicinal...

Hongjie Wang, Yongqiang Wu, Yong He, Guoyu Li, Lichao Ma, Shuo Li… in BMC Genomics (2023)

Article

Identification of mitochondrial respiratory chain signature for predicting prognosis and immunotherapy response in stomach adenocarcinoma

Stomach adenocarcinoma (STAD) is the third leading cause of cancer-related deaths and the fifth most prevalent malignancy worldwide. Mitochondrial respiratory chain complexes play a crucial role in STAD pathog...

**g Yang, Feifan **, Huanjuan Li, Yuhuan Shen, Weilin Shi… in Cancer Cell International (2023)

Article

Peripheral immune cell profiling of double-hit lymphoma by mass cytometry

Double-hit or Triple-hit lymphoma (DHL/THL) is a subset of high-grade B cell lymphoma harboring rearrangements of MYC and BCL2 and/or BCL6, and usually associate with aggressive profile, while current therapies t...

Tao Lei, Gongqiang Wu, Yong** Xu, Weihao Zhuang, Jialiang Lu, Shuiyun Han… in BMC Cancer (2023)

Article

Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival

The random-pattern skin flap is a crucial technique in reconstructive surgery and flap necrosis caused by ischemia/reperfusion injury is a major postoperative complication. Herein, we investigated the mechanis...

Zhengtai Chen, Hongqiang Wu, Jianxin Yang, Baolong Li, Jian Ding… in Communications Biology (2022)

Article

LRP4 is required for the olfactory association task in the piriform cortex

Low-density lipoprotein receptor-related protein 4 (LRP4) plays a critical role in the central nervous system (CNS), including hippocampal synaptic plasticity, maintenance of excitatory synaptic transmission, ...

Min Yan, Mingtao **ong, Yongqiang Wu, Dong Lin, Peng Chen, Jiang Chen… in Cell & Bioscience (2022)

Article

MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis

Intervertebral disc degeneration (IVDD) is a chronic age-related degenerative disease accompanied by complex pathophysiological mechanisms. Increasing evidence indicates that NLRP3 inflammasome mediated pyropt...

Haiwei Ma, Chenglong **e, Zhengtai Chen, Gaolu He, Zihan Dai… in Cell Death Discovery (2022)

Article

GBP2 facilitates the progression of glioma via regulation of KIF22/EGFR signaling

Identifying the mechanism of glioma progression is critical for diagnosis and treatment. Although studies have shown that guanylate-binding protein 2(GBP2) has critical roles in various cancers, its function i...

Yeqing Ren, Biao Yang, Geng Guo, Jian** Zhang, Yanqi Sun… in Cell Death Discovery (2022)

Article

Transmembrane protein 108 inhibits the proliferation and myelination of oligodendrocyte lineage cells in the corpus callosum

Abnormal white matter is a common neurobiological change in bipolar disorder, and dysregulation of myelination in oligodendrocytes (OLs) is the cause. Transmembrane protein 108 (Tmem108), as a susceptible gene of...

Yongqiang Wu, Yanzi Zhong, Xufeng Liao, **angguang Miao, Jianbo Yu… in Molecular Brain (2022)

Article

Massive pericardial effusion and pleural effusion: cardiac and pleural infiltration in newly diagnosed acute myeloid leukemia

Tao Ma, Hongyun **ng, **aofeng Zhu… in Journal of the Egyptian National Cancer In… (2021)

Article

Causes of death and effect of non-cancer-specific death on rates of overall survival in adult classic Hodgkin lymphoma: a populated-based competing risk analysis

The improved prognosis of classic Hodgkin lymphoma (cHL) has been accompanied by elevated risks of non–cancer-specific death (non-CSD). The aim of this study was to verify the occurrence of non-CSD and its eff...

Jie Gao, Yingying Chen, Pengqiang Wu, Fujue Wang, Huan Tao, Qianqing Shen… in BMC Cancer (2021)

Article

Degradation pathway of triazole fungicides and synchronous removal of transformation products via photo-electrocatalytic oxidation tandem MoS₂ adsorption

A simple and effective tandem process of photo-electrocatalytic oxidation (PECO)-MoS₂ adsorption was developed for the synchronous removal of triazole fungicides (TFs) and toxicological transformation products (T...

Junwen Wang, **aoxin Chen, **aoli Sun… in Environmental Science and Pollution Resear… (2021)

Article

Associations of sleep characteristics with atopic disease: a cross-sectional study among Chinese adolescents

Adolescence, as a transition between childhood and adulthood, is a critical stage for the long-term control of atopic diseases. We aim to determine if sleep characteristics are involved in the increased risk o...

Yiting Chen, Qian Yang, Kena Zhao, Zengqiang Wu… in Allergy, Asthma & Clinical Immunology (2021)