Jahrbuch Angewandte Hochschulbildung 2022
Deutsch-chinesische Perspektiven und Diskurse
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Article
Open AccessCryo-EM structures of adenosine receptor A3AR bound to selective agonists
The adenosine A3 receptor (A3AR), a key member of the G protein-coupled receptor family, is a promising therapeutic target for inflammatory and cancerous conditions. The selective A3AR agonists, CF101 and CF102, ...
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Article
Open AccessPromoter variations of ClERF1 gene determines flesh firmness in watermelon
Flesh firmness is a critical factor that influences fruit storability, shelf-life and consumer’s preference as well. However, less is known about the key genetic factors that are associated with flesh firmness...
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Article
Open AccessA simple and effective method to remove pigments from heterologous secretory proteins expressed in Pichia pastoris
Pichia pastoris is a popular yeast host for high-level heterologous expression of proteins on an industrial scale owing to its reliable expression, robust growth, high fermentation density, and easy genetic manip...
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Article
Food Effect on the Pharmacokinetics of VC004, a Tropomyosin Receptor Kinase Inhibitor: A Randomized Crossover Trial in Healthy Chinese Subjects
VC004 is a novel next-generation tropomyosin receptor kinase (TRK) inhibitor that is approved for the treatment of advanced or metastatic NTRK fusion-positive solid tumors and abrogated the drug resistance of ...
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Chapter and Conference Paper
Face Expression Recognition via Product-Cross Dual Attention and Neutral-Aware Anchor Loss
Face expression recognition is an important task whose aim is to classify a face image to a kind of expression such as happy, sad, or surprise, etc. This task is challenging due to the ambiguities in expressio...
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Book
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Article
Open AccessMolecular characterization and pathogenicity of an infectious clone of tomato leaf curl New Delhi virus isolate infecting Cucumis melo
Tomato leaf curl New Delhi virus (ToLCNDV) is a member of the genus Begomovirus, and causes devastating disease in the world. In recent years, ToLCNDV was rapidly spreading in China and induces severe economic lo...
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Article
Weakly-supervised instance co-segmentation via tensor-based salient co-peak search
Instance co-segmentation aims to segment the co-occurrent instances among two images. This task heavily relies on instance-related cues provided by co-peaks, which are generally estimated by exhaustively explo...
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Article
Open AccessTomato leaf curl New Delhi virus: an emerging plant begomovirus threatening cucurbit production
Tomato leaf curl New Delhi virus (ToLCNDV), a bipartite begomovirus, was first reported to infect tomato and has recently spread rapidly as an emerging disease to Cucurbitaceae crops. To date, the virus has been ...
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Article
Open AccessA electricity theft detection method through contrastive learning in smart grid
As an important edge device of power grid, smart meters enable the detection of illegal behaviors such as electricity theft by analyzing large-scale electricity consumption data. Electricity theft poses a majo...
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Article
Open AccessIdentification of essential proteins based on edge features and the fusion of multiple-source biological information
A major current focus in the analysis of protein–protein interaction (PPI) data is how to identify essential proteins. As massive PPI data are available, this warrants the design of efficient computing methods...
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Article
Effect of a moderate CYP3A inducer efavirenz on the pharmacokinetics of fuzuloparib: An open-label, fixed sequence study in Chinese healthy male subjects
To evaluate the potential drug-drug interaction (DDI), safety and tolerability of fuzuloparib co-administered with a moderate CYP3A inducer efavirenz in healthy male subjects. Eighteen healthy male subjects we...
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Article
Open AccessAn Online Mammography Database with Biopsy Confirmed Types
Breast carcinoma is the second largest cancer in the world among women. Early detection of breast cancer has been shown to increase the survival rate, thereby significantly increasing patients’ lifespan. Mammo...
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Article
Open AccessMolecular recognition of itch-associated neuropeptides by bombesin receptors
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Chapter and Conference Paper
Incremental Recommendation Algorithm Based on the Influence Propagation Model
Recently, Graph based recommendation algorithms have gained more and more attention due to their flexible and unified embedding representation of both users and items as well as the effective modeling of conte...
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Book
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Protocol
Fluorescence-Detection Size-Exclusion Chromatography-Based Thermostability Assay for Membrane Proteins
Green fluorescent proteins (GFPs) have lightened up almost every aspect of biological research including protein sciences. In the field of membrane protein structural biology, GFPs have been used widely to mon...
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Book
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Chapter and Conference Paper
Discovering Brain Network Dysfunction in Alzheimer’s Disease Using Brain Hypergraph Neural Network
Previous studies have shown that neurodegenerative diseases, specifically Alzheimer’s disease (AD), primarily affect brain network function due to neuropathological burdens that spread throughout the network, ...
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Chapter and Conference Paper
Multimodal Approaches for Alzheimer’s Detection Using Patients’ Speech and Transcript
Alzheimer’s disease (AD) is a common form of dementia that severely impacts patient health. As AD impairs the patient’s language understanding and expression ability, the speech of AD patients can serve as an ...
