20 Result(s)

Article

Biological characteristics of molecular subtypes of ulcerative colitis characterized by ferroptosis and neutrophil infiltration

Clinical ulcerative colitis (UC) is a heterogeneous condition. Moreover, medical interventions are nonspecific, and thus, treatment responses are inconsistent. The aim of this study was to explore the molecula...

Shaopeng Sun, Yuqing Mao, Sihua Le, Mingxu Zheng, Menglin Li… in Scientific Reports (2024)

Article

Undrained shear behavior of silty sand with a constant state parameter considering initial stress anisotropy effect

Field observations in sedimentation and erosion-prone areas indicate that most natural sand deposits may contain a certain amount of non-plastic fines and are often under anisotropic stress conditions. A serie...

Peipei Li, Chen Zhu, **aodong Pan, Bin Lv, Kun Pan in Scientific Reports (2024)

Article

A chromosome-level genome assembly of tomato pinworm, Tuta absoluta

The tomato pinworm, Tuta absoluta, or Phthorimaea absouta, is native to South America, but quickly spread to other regions of world, including Europe, Africa, and Asia, devastating to global tomato production....

Ying Liu, ** Chen, Yanqiong Yin, **aowei Li, Kang He, Xueqing Zhao… in Scientific Data (2023)

Article

A new protective gel to facilitate ulcer healing in artificial ulcers following oesophageal endoscopic submucosal dissection: a multicentre, randomized trial

There are significant risks of adverse events following oesophageal endoscopic submucosal dissection (ESD), such as stricture, delayed bleeding and perforation. Therefore, it is necessary to protect artificial...

Tianyu Zhou, **nli Mao, Lei Xu, Haifeng **, Li Cen, Caijuan Dong… in Scientific Reports (2023)

Article

Mitochondrial fission induces immunoescape in solid tumors through decreasing MHC-I surface expression

Mitochondrial dynamics can regulate Major Histocompatibility Complex (MHC)-I antigen expression by cancer cells and their immunogenicity in mice and in patients with malignancies. A crucial role in the mitocho...

**nyuan Lei, Hsinyu Lin, Jieqi Wang, Zhanpeng Ou, Yi Ruan… in Nature Communications (2022)

Article

Identification of AKIRIN2 as a potential biomarker and correlation with immunotherapy in gastric adenocarcinoma by integrated bioinformatics analysis

Gastric adenocarcinoma is major type of gastric cancer that endangers human health. AKIRIN2 has been shown to be associated with cholangiocarcinoma promoting invasion and angiogenesis. In this study, AKIRIN2 i...

Shaopeng Sun, Jiajia Chen, Chunyan Weng, Yifan Lu, Chang Cai, Bin Lv in Scientific Reports (2022)

Article

Author Correction: Climate variations of Central Asia on orbital to millennial timescales

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Hai Cheng, Christoph Spötl, Sebastian F. M. Breitenbach, Ashish Sinha… in Scientific Reports (2021)

Article

Author Correction: Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma

Yan Zhou, Dong Yang, Qingcheng Yang, **aobin Lv, Wentao Huang… in Nature Communications (2021)

Article

Quantitative analysis of contrast enhanced spectral mammography grey value for early prediction of pathological response of breast cancer to neoadjuvant chemotherapy

A quantitative analysis of contrast-enhanced spectral mammography (CESM) enhancement was conducted for the early prediction of the pathological response after neoadjuvant chemotherapy (NAC). Retrospective anal...

Dong **ng, Ning Mao, Jianjun Dong, Heng Ma, Qianqian Chen, Yongbin Lv in Scientific Reports (2021)

Article

Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma

Osteosarcoma is the most frequent primary bone tumor with poor prognosis. Through RNA-sequencing of 100,987 individual cells from 7 primary, 2 recurrent, and 2 lung metastatic osteosarcoma lesions, 11 major ce...

Yan Zhou, Dong Yang, Qingcheng Yang, **aobin Lv, Wentao Huang… in Nature Communications (2020)

Article

Co-expression of mFat-1 and pig IGF-1 genes by recombinant plasmids in modified chitosan nanoparticles and its synergistic effect on mouse immunity

To develop a cost-effective molecular regulator to improve growth metabolism and immunity of animals, a recombinant plasmid co-expressing fatty acid desaturase (mFat-1) and pig insulin growth like factor 1 (IG...

Qi **ong, Jianlin Chen, Fei-Lin Li, Shiji Zhao, ** Wan… in Scientific Reports (2017)

Article

Heart function and thoracic aorta gene expression profiling studies of ginseng combined with different herbal medicines in eNOS knockout mice

Ginseng, a popular herbal remedy, is often used in combination with other drugs to achieve the maximum therapeutic response. Shenfu (SFI) and Shenmai injection (SMI) have been widely used to treat cardiovascul...

Yuchen Qian, Pan Li, Bin Lv, **aoqing Jiang, Ting Wang, Han Zhang… in Scientific Reports (2017)

Article

Prenatal chromium exposure and risk of preterm birth: a cohort study in Hubei, China

Few studies have investigated the association of environmental chromium exposure and preterm birth in general population. This study was designed to investigate whether maternal chromium exposure during pregna...

**nyun Pan, Jie Hu, Wei **a, Bin Zhang, Wenyu Liu, Chuncao Zhang… in Scientific Reports (2017)

Article

Prognostic relevance of UCH-L1 and α-internexin in pancreatic neuroendocrine tumors

Prognostic biomarkers for the pancreatic neuroendocrine tumors are needed. Proteomic study on insulinoma has been rarely reported. We identified the differential expression of proteins between insulinoma and t...

Yu-Li Song, Run Yu, **n-Wei Qiao, Chun-Mei Bai, Chong-Mei Lu, Yu **ao… in Scientific Reports (2017)

Article

Evaluation of the Effects of Conjunctivochalasis Excision on Tear Stability and Contrast Sensitivity

Conjunctivochalasis (CCh) disrupts tear flow and damages tear film stability. This study sought to evaluate the tear stability and contrast sensitivity of patients with CCh on whom CCh excision was performed. ...

Weiqiang Qiu, Mingzhou Zhang, Ting Xu, Ziyuan Liu, Huibin Lv… in Scientific Reports (2016)

Article

Climate variations of Central Asia on orbital to millennial timescales

The extent to which climate variability in Central Asia is causally linked to large-scale changes in the Asian monsoon on varying timescales remains a longstanding question. Here we present precisely dated hig...

Hai Cheng, Christoph Spötl, Sebastian F. M. Breitenbach, Ashish Sinha… in Scientific Reports (2016)

Article

LncRNA PANDAR regulates the G1/S transition of breast cancer cells by suppressing p16^INK4A expression

It has been reported that lncRNA PANDAR (promoter of CDKN1A antisense DNA damage-activated RNA) is induced as a result of DNA damage, and it regulates the reparation of DNA damage. In this study, we investigat...

Yi Sang, Jianjun Tang, Siwei Li, Li** Li, **aoFeng Tang, Chun Cheng… in Scientific Reports (2016)

Article

SUN2 exerts tumor suppressor functions by suppressing the Warburg effect in lung cancer

SUN2, a key component of LINC (linker of nucleoskeleton and cytoskeleton) complex located at the inner nuclear membrane, plays unknown role in lung cancer. We found that SUN2 expression was decreased in lung c...

**ao-bin Lv, Lijuan Liu, Chun Cheng, Bentong Yu, Longxin **ong… in Scientific Reports (2015)